[ CSPS Pharmaceuticals, Inc. ] [ SPYDER ]


Articles thru 2003
Articles 2004
SPOS Papers
SPPS Papers
Graffiti Wall
Hot News
Site News


This list is arranged by the name of the first author. Please, note the change in numbering of the references. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (michal@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M., Leblova Z.: Dynamic database of references in molecular diversity. Internet http://www.5z.com.

Recently added entries are marked in bold

  1. Adams, C.L., Kochersperger, L.M., Mortensen, R.B., Aldwin, L.A. & Holmes, C.P. (1994) New methodologies in the preparation of peptide libraries. In J.W. Crabb (Ed.), Techniques in Protein Chemistry V. (pp. 525-532). Academic Press, San Diego. #1037

  2. Adleman, L.M. (1994) Molecular computation of solutions to combinatorial problems. Science, 266, 1021-1024. #5794

  3. Alper, J. (1994) Drug discovery on the assembly line. Science, 264, 1399-1401. #978

  4. Amaravadi, L., & King, M.W. (1994) A rapid and efficient, nonradioactive method for screening recombinant DNA libraries. BioTechniques, 16, 98-103. #800

  5. Ames, R.S., Tornetta, M.A., Jones, C.S., & Tsui, P. (1994) Isolation of neutralizing anti-C5a monoclonal antibodies from a filamentous phage monovalent Fab display library. Journal of Immunology, 152, 4572-4581. #934

  6. Andersson, B., Povinelli, C.M., Wentland, M.A., Shen, Y., Muzny, D.M., & Gibbs, R.A. (1994) Adaptor-based uracil DNA glycosylase cloning simplifies shotgun library construction for large-scale sequencing. Anal. Biochem., 218, 300-308. #823

  7. Andrews, P.C., Boyd, J., Ogorzalek-Loo, R.R., Zhao, R., Zhu, C.Q., Grant, K. & Williams, S. (1994) Synthesis of uniform peptide libraries and methods for physico-chemical analysis. In J.W. Crabb (Ed.), Techniques in Protein Chemistry V. (pp. 485-492). Academic Press, San Diego. #742

  8. Andrews, P.C., Leonard, D.M., Cody, W.L., & Sawyer, T.K. (1994) Multiple and combinatorial peptide synthesis. Chemical development and biological applications. Methods Mol. Biol., 36, 305-328. #2689

  9. Ator, M.A., Beigel, S., Dankanich, T.C., Echols, M., Gainor, J.A., Gilliam, C.L., Gordon, T.D., Koch, D., Koch, J.F., Kruse, L.I., Morgan, B.A., Krupinski-Olsen, R., Siahaan, T.J., Singh, J. & Whipple, D.A. (1994) Immobilized peptide arrays: A new technology for the characterization of protease function. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1012-1015). ESCOM, Leiden. #504

  10. Backes, B.J., & Ellman, J.A. (1994) Carbon-carbon bond-forming methods on solid support. Utilization of Kenner's "Safety-Catch" linker. J. Amer. Chem. Soc., 116, 11171-11172. #2039

  11. Bagley, J., Dillon, P.J., Rosen, C., Robinson, J., Sodroski, J., & Marasco, W.A. (1994) Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120. Mol. Immunol., 31, 1149-1160. #2253

  12. Barbas, C.F.I., Hu, D., Dunlop, N., Sawyer, L., Cababa, D., Hendry, R.M., Nara, P.L., & Burton, D.R. (1994) In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity. Proc. Natl. Acad. Sci. USA, 91, 3809-3813. #786

  13. Barbas, S.M., & Barbas, C.F. (1994) Filamentous phage display. Fibrinolysis, 8, 245-252. #2247

  14. Barbas, S.M., Ghazal, P., Barbas, C.F., & Burton, D.R. (1994) Recognition of DNA by synthetic antibodies. J. Amer. Chem. Soc., 116, 2161-2162. #5906

  15. Bartak, Z., Bolf, J., Kalousek, J., Mudra, P., Pavlik, M., Pokorny, V., Rinnova, M., Voburka, Z., Zenisek, K., Krchnak, V., Lebl, M., Salmon, S.E., & Lam, K.S. (1994) Design and construction of the automatic peptide library synthesizer. Methods: A Companion to Methods in Enzymology, 6, 432-437. #1011

  16. Baum, R.M. (1994) Combinatorial approaches provide fresh leads for medicinal chemistry. C&EN, 20-26. #980

  17. Baum, R.M. (1994) Random library of myoglobin mutants probes protein properties. C&EN, 49-49. #979

  18. Bayley, H. (1994) Self-assembling biomolecular materials in medicine. J. Cell. Biochem., 56, 168-170. #2248

  19. Beattie, K.L. & Hurst, G.D. (1994) Synthesis and use of oligonucleotide libraries. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 69-76). Mayflower Worldwide Limited, Birmingham. #1854

  20. Beck, W., & Jung, G. (1994) Convenient reduction of S-oxides in synthetic peptides, lipopeptides and peptide libraries. Lett. Peptide Sci., 1, 31-37. #2691

  21. Beeley, N. (1994) Peptidomimetics and small-molecule drug design: Towards improved bioavailability and in vivo stability. Trends Biotech., 12, 213-216. #5249

  22. Bender, E., Pilkington, G.R., & Burton, D.R. (1994) Human monoclonal Fab fragments from combinatorial library prepared from an individual with a low serum titer to a virus. Hum. Antibodies. Hybridomas., 5, 3-8. #4713

  23. Bertioli, D.J., Smoker, M., Brown, A.C.P., Jones, M.G.K., & Burrows, P.R. (1994) A method based on PCR for the construction of cDNA libraries and probes from small amounts of tissue. BioTechniques, 16, 1054-1058. #5240

  24. Blaney, J.M., Ciani, M.A., & Weininger, D. (1994) Managing data from combinatorial experiments. Abstract. Paper. ACS, 208, 122-122. #765

  25. Blondelle, S.E. & Houghten, R.A. (1994) Membrane protecting sequences and new antimicrobial peptides identified through the screening of synthetic peptide combinatorial libraries. In J.W. Crabb (Ed.), Techniques in Protein Chemistry V. (pp. 509-516). Academic Press, San Diego. #499

  26. Blondelle, S.E., Takahashi, E., Weber, P.A., & Houghten, R.A. (1994) Identification of antimicrobial peptides using combinatorial libraries made up of unnatural amino acids. Antimicrob. Agents Chemother., 38, 2280-2286. #1947

  27. Blondelle, S.E., Simpkins, L.R. & Houghten, R.A. (1994) Inhibitors of cytolytic compounds identified using synthetic peptide libraries. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 163-168). Mayflower Worldwide Limited, Birmingham. #569

  28. Boden, P., Eden, J.M., Hodgson, J., Horwell, D.C., Howson, W., Hughes, J., McKnight, A.T., Meecham, K., Pritchard, M.C., Raphy, J., Ratcliffe, G.S., Suman-Chauhan, N., & Woodruff, G.N. (1994) The rational development of small molecule tachykinin NK(3) receptor selective antagonists.The utilisation of a dipeptide chemical library in drug design. Bioorg. Med. Chem. Lett., 4, 1679-1684. #1955

  29. Bohacek, R.S., & McMartin, C. (1994) Multiple highly diverse structures complementary to enzyme binding sites: Results of extensive application of a de novo design method incorporating combinatorial growth. J. Amer. Chem. Soc., 116, 5560-5571. #6006

  30. Borchardt, A., & Still, W.C. (1994) Synthetic receptor binding elucidated with an encoded combinatorial library. J. Amer. Chem. Soc., 116, 373-374. #773

  31. Borchardt, A., & Still, W.C. (1994) Synthetic receptor for internal residues of a peptide chain. Highly selective binding of (L)X-(L)Pro-(L)X tripeptides. J. Amer. Chem. Soc., 116, 7467-7468. #1124

  32. Borman, S. (1994) Synthetic receptors bind peptides selectivity. C&EN, 5-5. #1531

  33. Borman, S. (1994) Military research on cubane explosives may also lead to new pharmaceuticals. C&EN, 34-36. #2038

  34. Borman, S. (1994) Combinatorial chemistry used to probe binding. C&EN, 37-38. #2677

  35. Bottger, V., & Lane, E.B. (1994) A monoclonal antibody epitope on keratin-8 identified using a phage peptide library. J. Mol. Biol., 235, 61-67. #914

  36. Boyce, R., Li, G., Nestler, H.P., Suenaga, T., & Still, W.C. (1994) Peptidosteroidal receptors for opioid peptides. Sequence-selective binding using a synthetic receptor library. J. Amer. Chem. Soc., 116, 7955-7956. #1313

  37. Brady, P.A., & Sanders, J.K. (1994) Thermodynamically-controlled cyclisation and interconversion of oligocholates: Metal ion templated living macrolactonisation. J. Chem. Soc., 3237-3253. #10125

  38. Bray, A.M., Lagniton, L.M., Valerio, R.M., & Maeji, N.J. (1994) Sonication-assisted cleavage of hydrophobic peptides. Application in multipin peptide synthesis. Tetrahedron Lett., 35, 9079-9082. #2679

  39. Bray, A.M., Jhingran, A.G., Valerio, R.M., & Maeji, N.J. (1994) Simultaneous multiple synthesis of peptide amides by the multipin method. Application of vapor-phase ammonolysis. J. Org. Chem., 59, 2197-2203. #982

  40. Briley, G.P., & Bidwell, C.A. (1994) Use of agarose block DNA to make cosmid libraries. BioTechniques, 17, 278-280. #1958

  41. Brugghe, H.F., Timmermans, H.A.M., van Unen, L.M.A., Hove, G.J.T., van de Werken, G., Poolman, J.T., & Hoogerhout, P. (1994) Simultaneous multiple synthesis and selective conjugation of cyclized peptides derived from a surface loop of a meningococcal class 1 outer membrane protein. Int. J. Peptide Prot. Res., 43, 166-172. #938

  42. Brummel, C.L., Lee, I.N.W., Zhou, Y., Benkovic, S.J., & Winograd, N. (1994) A mass spectrometric solution to the address problem of combinatorial libraries. Science, 264, 399-402. #788

  43. Buettner, J.A., Hudson, D., Johnson, C.R., Ross, M.J. & Shoemaker, K. (1994) Pharmaceutically relevant peptide synthesis methods pilot, a new library and lead optimization technique. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 169-174). Mayflower Worldwide Limited, Birmingham. #1856

  44. Bunin, B.A., Plunkett, M.J., & Ellman, J.A. (1994) The combinatorial synthesis and chemical and biological evaluation of 1,4-benzodiazepine library. Proc. Natl. Acad. Sci. USA, 91, 4708-4712. #1041

  45. Bunin, B.A., & Ellman, J.A. (1994) Increasing the diversity of a 1,4-benzodiazepine library through side-chain functionalization. Polym. Preprint., 35, 983-984. #2163

  46. Burgess, K., Liaw, A.I., & Wang, N. (1994) Combinatorial technologies involving reiterative division/coupling/recombination: Statistical considerations. J. Med. Chem., 37, 2985-2987. #1321

  47. Burton, D.R., & Barbas, C.F.I. (1994) Human antibodies from combinatorial libraries. Adv. Immunol., 57, 191-280. #2703

  48. Callen, A.M., Adoutte, A., Andrew, J.M., Barointourancheau, A., Bre, M.H., Ruiz, P.C., Clerot, J.C., Delgado, P., Fleury, A., Jeanmairewolf, R., Viklicky, V., Villalobo, E., & Levilliers, N. (1994) Isolation and characterization of libraries of monoclonal antibodies directed against various forms of tubulin in Paramedicium. Biol. Cell, 81, 95-119. #2271

  49. Campian, E., Sebestyen, F. & Furka, A. (1994) Colored and fluorescent solid supports. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 469-472). Mayflower Worldwide Limited, Birmingham. #1871

  50. Campian, E., Sebestyen, F., Major, F., & Furka, A. (1994) Synthesis of support-bound peptides carrying color labels. Drug Develop. Res., 33, 98-101. #1896

  51. Carell, T., Wintner, E.A., Bashir-Hashemi, A., & Rebek, J.Jr. (1994) A novel procedure for the synthesis of libraries containing small organic molecules. Angew. Chem. Int. Ed., 33, 2059-2061. #2043

  52. Carell, T., Wintner, E.A., & Rebek, J.Jr. (1994) A solution-phase screening procedure for the isolation of active compounds from a library of molecules. Angew. Chem. Int. Ed., 33, 2061-2064. #2044

  53. Case-Green, S.C., Elder, J.K., Mir, K.U., Maskos, U., Southern, E.M. & Williams, J.C. (1994) Parallel synthesis and analysis: Application of spatially addressable oligonucleotide arrays. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 77-82). Mayflower Worldwide Limited, Birmingham. #1855

  54. Cason, J. (1994) Strategies for mapping and imitating viral b-cell epitopes. J. Virol. Meth., 49, 209-220. #2252

  55. Cass, R., Dreyer, M.L., Giebel, L.B., Hudson, D., Johnson, C.R., Ross, M.J., Schaeck, J. & Shoemaker, K.R. (1994) Pilot, a new peptide lead optimization technique and its application as a general library method. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 975-977). ESCOM, Leiden. #1021

  56. Chen, C.X., Ahlberg Randall, L.A., Miller, R.B., Jones, A.D., & Kurth, M.J. (1994) "Analogous" organic synthesis of small-compound libraries: Validation of combinatorial chemistry in small-molecule synthesis. J. Amer. Chem. Soc., 116, 2661-2662. #1952

  57. Chen, C.Z., Xia, Q.C., Li, B.L., & Wang, Y.L. (1994) Selection of substrate recognition sequence of protein kinase with ferric chelation affinity chromatography. Sci. China Ser. B, 184-193. #9288

  58. Chester, K.A., Begent, R.H.J., Robson, L., Keep, P., Pedley, R.B., Boden, J.A., Boxer, G., Green, A., Winter, G., Cochet, O., & Hawkins, R.E. (1994) Phage libraries for generation of clinically useful antibodies. Lancet, 343, 455-456. #918

  59. Chetverin, A.B., & Kramer, F.R. (1994) Oligonucleotide arrays: New concepts and possibilities. Biotechnology, 12, 1093-1099. #11116

  60. Cianfriglia, M., Willingham, M.C., Tombesi, M., Scagliotti, G.V., Frasca, G., & Chersi, A. (1994) P-Glycoprotein epitope mapping. I.Identification of a linear human-specific epitope in the fourth loop of the P-glycoprotein extracellular domain by MM4.17 murine monoclonal antibody to human multi-drug-resistant cells. Int. J. Cancer, 56, 153-160. #4734

  61. Clackson, T., & Wells, J.A. (1994) In vitro selection from protein and peptide libraries. Trends Biotech., 12, 173-184. #2610

  62. Coffen, D.L., Huang, T.N., Ramer, S.E., West, R.C., Connell, E.V., Schutt, A.D., & Hsu, M.C. (1994) Discovery of a drug lead employing a peptide library.Inhibition of HIV-1 tat and viral replication by the tripeptide YPG-NH2. Antivir. Chem. Chemother., 5, 128-129. #923

  63. Cortese, R., Felici, F., Galfre, G., Luzzago, A., Monaci, P., & Nicosia, A. (1994) Epitope discovery using peptide libraries displayed on phage. Trends Biotech., 12, 262-267. #2925

  64. Costante, G., Portolano, S., Nishikawa, T., Jaume, J.C., Chazenbalk, G.D., Rapoport, B., & McLachlan, S.M. (1994) Recombinant thyroid peroxidase-specific autoantibodies.II. Role of individual heavy and light chains in determining epitope recognition. Endocrinology, 135, 25-30. #4665

  65. Crowe, J.E.J., Murphy, B.R., Chanock, R.M., Williamson, R.A., Barbas, C.F.I., & Burton, D.R. (1994) Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice. Proc. Natl. Acad. Sci. USA, 91, 1386-1390. #4669

  66. Danheiser, S.L. (1994) Current trends in synthetic peptide and chemical diversity library design. Gen. Eng. News, 14, 10-31. #983

  67. Darlak, K., Romanovskis, P. & Spatola, A.F. (1994) Cyclic peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 981-983). ESCOM, Leiden. #1019

  68. Davidson, A.R., & Sauer, R.T. (1994) Folded proteins occur frequently in libraries of random amino acid sequences. Proc. Natl. Acad. Sci. USA, 91, 2146-2150. #925

  69. De Vouge, M.W., Yamazaki, A., Bennett, S.A.L., Chen, J.H., Shwed, P.S., Couture, C., & Birnboim, H.C. (1994) Immunoselection of GRP94/endoplasmin from a KNRK cell-specific lambda gt11 library using antibodies directed against a putative heparanase amino-terminal peptide. Int. J. Cancer, 56, 286-294. #921

  70. de Vries, D.J., & Hall, M.R. (1994) Marine biodiversity as a source of chemical diversity. Drug Develop. Res., 33, 161-173. #1901

  71. Dean, P.M. (1994) Recent advances in drug design methods: Where will they lead? Bioessays, 16, 683-687. #2246

  72. Del Rio, G., Osuna, J., & Soberon, X. (1994) Combinatorial libraries of proteins: Analysis of efficiency of mutagenesis techniques. BioTechniques, 17, 1132-1139. #2040

  73. Dennis, M.S., & Lazarus, R.A. (1994) Kunitz domain inhibitors of tissue factor-factor VIIa .1. Potent inhibitors selected from libraries by phage display. Journal of Biological Chemistry, 269, 22129-22136. #1943

  74. Dente, L., Cesareni, G., Micheli, G., Felici, F., Folgori, A., Luzzago, A., Monaci, P., Nicosia, A., & Delmastro, P. (1994) Monoclonal antibodies that recognise filamentous phage: Tools for phage display technology. Gene, 148, 7-13. #2255

  75. Desai, M.C., Zuckermann, R.N., & Moos, W.H. (1994) Recent advances in the generation of chemical diversity libraries. Drug Develop. Res., 33, 174-188. #1902

  76. Deshpande, M.S. (1994) Formation of carbon-carbon bond on solid support: Application of Stille reaction. Tetrahedron Lett., 35, 5613-5614. #1315

  77. Desjarlais, J.R., & Berg, J.M. (1994) Lenght-encoded multiplex binding site determination: Application to zinc finger proteins. Proc. Natl. Acad. Sci. USA, 91, 11099-11103. #1000

  78. Devries, D.J., & Hall, M.R. (1994) Marine biodiversity as a source of chemical diversity. Drug Develop. Res., 33, 161-173. #6290

  79. DeWitt, S.H., Schroeder, M.C., Stankovic, C.J., Strode, J.E., & Czarnik, A.W. (1994) DIVERSOMER(TM) technology: Solid phase synthesis, automation, and integration for the generation of chemical diversity. Drug Develop. Res., 33, 116-124. #1898

  80. DeWitt, S.H. (1994) Molecular diversity strategies. Pharmaceut. News, 1, 11-14. #2422

  81. Dimond, P.F. (1994) Pharmacopeia Inc.'s novel molecular tagging system finds molecules. Gen. Eng. News, 14, 32-38. #984

  82. Ditzel, H.J., Barbas, S.M., Barbas, C.F.I., & Burton, D.R. (1994) The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection. Proc. Natl. Acad. Sci. USA, 91, 3710-3714. #4668

  83. Domanico, P.L. (1994) Discovery research: Innovation and automation. Chemometr. Intell. Lab. Syst., 26, 115-121. #2675

  84. Dooley, C.T. & Houghten, R.A. (1994) New, potent N-acetylated all D-amino acid opioid peptides. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 984-985). ESCOM, Leiden. #716

  85. Dooley, C.T., Hope, S., & Houghten, R.A. (1994) Rapid identification of novel opioid peptides from an N- acetylated synthetic combinatorial library. Regul. Peptides, 54, 87-88. #2256

  86. Dooley, C.T., Chung, N.N., Wilkes, B.C., Schiller, P.W., Bidlack, J.M., Pasternak, G.W., & Houghten, R.A. (1994) An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library. Science, 266, 2019-2022. #2075

  87. Doorbar, J., & Winter, G. (1994) Isolation of a peptide antagonist to the thrombin receptor using phage display. J. Mol. Biol., 244, 361-369. #2275

  88. du Plessis, D.H., Wang, L.F., Jordaan, F.A., & Eaton, B.T. (1994) Fine mapping of a continuous epitope on VP7 of bluetongue virus using overlapping synthetic peptides and a random epitope library. Virology, 198, 346-349. #931

  89. Eckes, P. (1994) Binary encoding of compound libraries. Angew. Chem. Int. Ed., 33, 1573-1575. #1942

  90. Eichbaum, Q.G., Beatty, D.W., & Parker, M.I. (1994) Identification of cardiac autoantigens in human heart cDNA libraries using acute rheumatic fever sera. J. Autoimmun., 7, 243-261. #843

  91. Eichler, J., Lucka, A.W., & Houghten, R.A. (1994) Cyclic peptide template combinatorial libraries: Synthesis and identification of chymotrypsin inhibitors. Peptide Res., 7, 300-307. #2042

  92. Eichler, J., Pinilla, C., Chendra, S., Appel, J.R. & Houghten, R.A. (1994) Synthesis of peptide libraries on cotton carriers: Methods and applications. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 227-232). Mayflower Worldwide Limited, Birmingham. #1859

  93. Ellington, A.D. (1994) Using in vitro nucleic acid selections for conventional drug design. Drug Develop. Res., 33, 102-115. #1897

  94. Epton, R. (1994) Innovation and Perspectives in Solid Phase Synthesis. Mayflower Scientific Limited, Birmingham. ISBN 0951573519 #13447

  95. Erb, E., Janda, K.D., & Brenner, S. (1994) Recursive deconvolution of combinatorial chemical libraries. Proc. Natl. Acad. Sci. USA, 91, 11422-11426. #1923

  96. Estaquier, J., Gras-Masse, H., Boutillon, C., Ameisen, J.C., Capron, A., Tartar, A., & Auriault, C. (1994) The mixotope: A combinatorial peptide library as a T cell and B cell immunogen. Eur. J. Immunol., 24, 2789-2795. #2678

  97. Famulok, M., & Faulhammer, D. (1994) Specific binding of antibodies to DNA through combinatorial antibody libraries. Angew. Chem. Int. Ed., 33, 1827-1829. #2119

  98. Fassina, G., Bellitti, M.R., & Cassani, G. (1994) Screening synthetic peptide libraries with targets bound to magnetic beads. Protein Peptide Lett., 1, 15-18. #1031

  99. Feiertag, S., Gnau, V., Udaka, K., Walden, P., Jung, G. & Wiesmuller, K.H. (1994) Coupling method for X-positions in octapeptide mixtures applied in competition experiments with killer cells. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 501-504). Mayflower Worldwide Limited, Birmingham. #1872

  100. Felder, E.R. (1994) The challenge of preparing and testing combinatorial compound libraries in the fast lane, at the front end of drug development. Chimia, 48, 531-541. #2415

  101. Fink, L.M., & Hsu, P.L. (1994) Bacteriophage epitope libraries: The generation of specific binding proteins and peptides in vitro. Virchows Archiv, 424, 1-6. #1959

  102. Fischer, P., Leu, S.J.C., Yang, Y.Y., & Chen, P.P. (1994) Rapid simultaneous screening for DNA integrity and antigen specificity of clones selected by phage display. BioTechniques, 16, 828-830. #802

  103. Fitch, W.L., Detre, G., & Holmes, C.P. (1994) High-resolution (1)H NMR in solid-phase organic synthesis. J. Org. Chem., 59, 7955-7956. #2141

  104. Fleckenstein, B., Wiesmuller, K.H., Brich, M., & Jung, G. (1994) Novel heterobifunctionalized polystyrene-polyethylene glycol resin for simultaneous preparation of free and immobilized peptides and biological activity detected by confocal microscopy. Lett. Peptide Sci., 1, 117-126. #1850

  105. Folgori, A., Tafi, R., Meola, A., Felici, F., Galfre, G., Cortese, R., Monaci, P., & Nicosia, A. (1994) A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO J., 13, 2236-2243. #816

  106. Fong, S., Doyle, L.V., Devlin, J.J., & Doyle, M.V. (1994) Scanning whole cells with phage display libraries: Identification of peptide ligands that modulate cell function. Drug Develop. Res., 33, 64-70. #1893

  107. Frank, R. (1994) SPOT-synthesis: An easy and flexible tool to study molecular recognition. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 509-512). Mayflower Worldwide Limited, Birmingham. #719

  108. Frenette, R., & Friesen, R.W. (1994) Biaryl synthesis via Suzuki coupling on a solid support. Tetrahedron Lett., 35, 9177-9180. #2029

  109. Fu, H., Hopwood, D.A., & Khosla, C. (1994) Engineered biosynthesis of novel polyketides: Evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor. Chem. Biol., 1, 205-210. #3514

  110. Furka, A. (1994) Sub-library composition of peptide libraries: Potential application in screening. Drug Develop. Res., 33, 90-97. #1895

  111. Furka, A., Sebestyen, F. & Campian, E. (1994) Peptide sub-library kits. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 385-390). Mayflower Worldwide Limited, Birmingham. #1868

  112. Furka, A., Sebestyen, F. & Campian, E. (1994) The use of sub-library kits in a new screening strategy. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 986-988). ESCOM, Leiden. #527

  113. Furlan, R.L.E., Mata, E.G., & Mascaretti, O.A. (1994) Efficient, non-acidolytic method for the selective cleavage of N-Boc amino acid and peptide phenacyl esters linked to a polystyrene resin. J. Chem. Soc. Perkin Trans. 1, 355-358. #10686

  114. Gainor, J.A., Gordon, T.D. & Morgan, B.A. (1994) The synthesis and coupling efficiency of 7-hydroxycoumarin-4-propionic acid, a fluorescent marker useful in immobilized substrate libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 989-991). ESCOM, Leiden. #1018

  115. Gallop, M.A., Barrett, R.W., Dower, W.J., Fodor, S.P.A., & Gordon, E.M. (1994) Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries. J. Med. Chem., 37, 1233-1251. #833

  116. Gallop, M.A. (1994) Generation of binary-encoded combinatorial libraries and their applications to ligand discovery. Chemtracts:Org. Chem., 7, 172-178. #1842

  117. Gao, F.B., Carson, C.C., Levine, T., & Keene, J.D. (1994) Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1. Proc. Natl. Acad. Sci. USA, 91, 11207-11211. #2019

  118. Gavin, M.A., Dere, B., Grandea, A.G.I., Hogquist, K.A., & Bevan, M.J. (1994) Major histocompatibility complex class I allele-specific peptide libraries: Identification of peptides that mimic an H-Y T cell epitope. Eur. J. Immunol., 24, 2124-2133. #1949

  119. Geysen, H.M. (1994) Combinatorial peptide libraries for the delineation of antibody reactive epitopes. Pathol. Biol., 42, 795-795. #2258

  120. Geysen, M. Diversity biotechnology consortium searches for "irrational" cures. 1994. #13744

  121. Ghosh, S., DeWitt, S.H., Mei, H.Y., Sanders, K., & Czarnik, A.W. (1994) Multiple synthesis of cyclic oligonucleotides using diversomer (Tm) technology. Abstract. Paper. ACS, 208, 240-240. #774

  122. Goldman, E.R., Fullen, G., & Youvan, D.C. (1994) Estimating protein function from combinatorial sequence data using decision algorithms and neural networks. Drug Develop. Res., 33, 125-132. #1899

  123. Goodson, R.J., Doyle, M.V., Kaufman, S.E., & Rosenberg, S. (1994) High-affinity urokinase receptor antagonists identified with bacteriophage peptide display. Proc. Natl. Acad. Sci. USA, 91, 7129-7133. #2318

  124. Gordeev, M.F., Patel, D.V., Barker, P.L., & Gordon, E.M. (1994) N-a-Fmoc-4-phosphono(difluoromethyl)-L-phenylalanine: A new O-phosphotyrosine isosteric building block suitable for direct incorporation into peptides. Tetrahedron Lett., 35, 7585-7588. #6538

  125. Gordon, E.M., Barrett, R.W., Dower, W.J., Fodor, S.P.A., & Gallop, M.A. (1994) Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions. J. Med. Chem., 37, 1385-1401. #1001

  126. Graham, L.D., Haggett, K.D., Hayes, P.J., Schober, P.A., Jennings, P.A., & Whittaker, R.G. (1994) A new library of alpha-lytic protease S-1 mutants generated by combinatorial random substitution. Biochem. Mol. Biol. Int., 32, 831-839. #5242

  127. Green, M., McGeehan, G.M., Anderegg, R.S., Bickett, D.M., Kassel, D., Aquino, C.J., Sugg, E.E., Millington, S., Norwod, D.L., Wiseman, J.S. & Bermann, J. (1994) Protease substrate mapping. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 239-244). Mayflower Worldwide Limited, Birmingham. #1860

  128. Grothues, D., Cantor, C.R., & Smith, C.L. (1994) Top-down construction of an ordered Schizosaccharomyces pombe cosmid library. Proc. Natl. Acad. Sci. USA, 91, 4461-4465. #820

  129. Hebert, N., Davis, P.W., DeBaets, E.L., & Acevedo, O.L. (1994) Synthesis of N-substituted hydroxyprolinol phosphoramidites for the preparation of combinatorial libraries. Tetrahedron Lett., 35, 9509-9512. #2078

  130. Hexham, J.M., Partridge, L.J., Furmaniak, J., Petersen, V.B., Colls, J.C., Pegg, C., Rees, S.B., & Burton, D.R. (1994) Cloning and characterisation of TPO autoantibodies using combinatorial phage display libraries. Autoimmunity, 17, 167-179. #1957

  131. Hoess, R.H., Mack, A.J., Walton, H., & Reilly, T.M. (1994) Identification of a structural epitope by using a peptide library displayed on filamentous bacteriophage. Journal of Immunology, 153, 724-729. #1961

  132. Hoffmann, S. & Frank, R. (1994) A new type of reversible peptide-resin linkage for the direct release of peptides into aqueous buffers. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 535-538). Mayflower Worldwide Limited, Birmingham. #1873

  133. Hoffmann, S., & Frank, R. (1994) A new safety-catch peptide-resin linkage for the direct release of peptides into aqueous buffers. Tetrahedron Lett., 35, 7763-7766. #1841

  134. Holmes, C.P. & Rybak, C.M. (1994) Peptide reversal on solid supports: A technique for the generation of C-terminal exposed peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 992-994). ESCOM, Leiden. #1016

  135. Holmes, C.P. & Fodor, S.P.A. (1994) Photolithography and combinatorial chemistry in screening. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 221-226). Mayflower Worldwide Limited, Birmingham. #1858

  136. Hong, F., Zaidi, J., Pang, Y.P., Cusack, B., & Richelson, E. (1994) Design, synthesis and pharmacological evaluation of active pyrrole based, nonpeptidic analogues of neurotensin(8-13). J. Chem. Soc., 2997-3003. #10218

  137. Hornik, V., & Hadas, E. (1994) Self-encoded, highly condensed solid phase-supported peptide library for identification of ligand-specific peptides. React. Polym., 22, 213-220. #1462

  138. Horwell, D.C., Lennon, I.C., & Roberts, E. (1994) Alternative strategies towards the identification of chemical lead compounds by rational design. Bioorg. Med. Chem. Lett., 4, 525-530. #2598

  139. Houghten, R.A. (1994) Combinatorial libraries: Finding the needle in the haystack. Curr. Biol., 4, 564-567. #1965

  140. Houghten, R.A., Appel, J.R., Blondelle, S.E., Cuervo, J.H., Dooley, C.T., Eichler, J. & Pinilla, C. (1994) Optimal peptide length determination using synthetic peptide combinatorial libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 971-974). ESCOM, Leiden. #715

  141. Houghten, R.A. (1994) Soluble combinatorial libraries: Extending the range and repetoire of chemical diversity. Methods: A Companion to Methods in Enzymology, 6, 354-360. #572

  142. Houghten, R.A. (1994) Combinatorial libraries: Current capabilities and future possibilities. Pharm. Manufact., 55-57. #8683

  143. Hughes-Jones, N.C., Gorick, B.D., Bye, J.M., Finnern, R., Scott, M.L., Voak, D., Marks, J.D., & Ouwehand, W.H. (1994) Characterization of human blood group scFv antibodies derived from a V gene phage-display library. Brit. J. Haematol., 88, 180-186. #1939

  144. Hughes, D.E. (1994) Capillary electrophoretic examination of underivatized O-linked and N-linked oligosaccharide mixtures and immunoglobulin G antibody-released oligosaccharide libraries. J. Chromatogr. B Biomed. Sci. Appl., 657, 315-326. #1954

  145. Ihlenfeldt, H.G., Kraas, W., Seidel, C., Wienhus, U. & Jung, G. (1994) Comparison of two different methods for epitope mapping: Pin technology and biotinylated peptides. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 555-558). Mayflower Worldwide Limited, Birmingham. #1874

  146. Jacobs, J.W., & Fodor, S.P.A. (1994) Combinatorial chemistry: Applications of light-directed chemical synthesis. Trends Biotech., 12, 19-26. #2148

  147. Janda, K.D. (1994) Tagged versus untagged libraries: Methods for the generation and screening of combinatorial chemical libraries. Proc. Natl. Acad. Sci. USA, 91, 10779-10785. #1922

  148. Janda, K.D., Lo, C.H.L., Li, T., Barbas, C.F.I., Wirsching, P., & Lerner, R.A. (1994) Direct selection for a catalytic mechanism from combinatorial antibody libraries. Proc. Natl. Acad. Sci. USA, 91, 2532-2536. #790

  149. Jaume, J.C., Constante, G., Portolano, S., McLachlan, S.M., & Rapoport, B. (1994) Recombinant thyroid peroxidase-specific autoantibodies. I.How diverse is the pool of heavy and light chains in immunoglobulin gene libraries constructed from thyroid tissue-infiltrating plasma cells? Endocrinology, 135, 16-24. #4667

  150. Jayawickreme, C.K., Quillan, J.M., Graminski, G.F., & Lerner, M.R. (1994) Discovery and structure-function analysis of a-melanocyte-stimulating hormone antagonists. Journal of Biological Chemistry, 269, 29846-29854. #3421

  151. Jayawickreme, C.K., Graminski, G.F., Quillan, J.M., & Lerner, M.R. (1994) Creation and functional screening of a multi-use peptide library. Proc. Natl. Acad. Sci. USA, 91, 1614-1618. #799

  152. Jellinek, D., Green, L.S., Bell, C., & Janjic, N. (1994) Inhibition of receptor binding by high-affinity RNA ligands to vascular endothelial growth factor. Biochemistry, 33, 10450-10456. #2021

  153. Jenison, R.D., Gill, S.C., Pardi, A., & Poliski, B. (1994) High-resolution molecular discrimination by RNA. Science, 263, 1425-1429. #2363

  154. Jeong, S.K. (1994) New drug screening and peptide library. Hwahak Sekye, 34, 18-19. #2616

  155. Jezek, J., & Houghten, R.A. (1994) A comparative study of BOP as a coupling agent using simultaneous multiple peptide synthesis. Collect. Czech. Chem. Commun., 59, 691-706. #2615

  156. Kandpal, R.P., Kandpal, G., & Weissman, S.M. (1994) Construction of libraries enriched for sequence repeats and jumping clones, and hybridization selection for region-specific markers. Proc. Natl. Acad. Sci. USA, 91, 88-92. #916

  157. Kania, R.S., Zuckermann, R.N., & Marlowe, C.K. (1994) Free C-terminal resin-bound peptides: Reversal of peptide orientation via a cyclization/cleavage protocol. J. Amer. Chem. Soc., 116, 8835-8836. #1355

  158. Kao, C.M., Katz, L., & Khosla, C. (1994) Engineered biosynthesis of a complete macrolactone in a heterologous host. Science, 265, 509-512. #3152

  159. Karu, A.E., Scholthof, K.B.G., Zhang, G., & Bell, C.W. (1994) Recombinant antibodies to small analytes and prospects for deriving them from synthetic combinatorial libraries. Food Agric. Immunol., 6, 277-286. #2687

  160. Kauffman, S. (1994) 4.Protein mediated networks. Random chemistry. Ber. Bunsen Ges. Phys. Chem., 98, 1142-1147. #2025

  161. Kazmierski, W.M. (1994) Recent advances in the design and synthesis of small-molecule mimetic drugs. Trends Biotech., 12, 216-218. #5248

  162. Kenan, D.J., Tsai, D.E., & Keene, J.D. (1994) Exploring molecular diversity with combinatorial shape libraries. Trends Biochem. Sci., 19, 57-64. #917

  163. Kettleborough, C.A., Ansell, K.H., Allen, R.W., Rosell-Vives, E., Gussow, D.H., & Bendig, M.M. (1994) Isolation of tumor cell-specific single-chain Fv from immunized mice using phage-antibody libraries and the re-construction of whole antibodies from these antibody fragments. Eur. J. Immunol., 24, 952-958. #933

  164. Koivunen, E., Wang, B.C., & Ruoslahti, E. (1994) Isolation of a highly specific ligand for the a(5)b(1) integrin from a phage display library. J. Cell Biol., 124, 373-380. #922

  165. Kramer, A., Schuster, A., Reineke, U., Malin, R., Volkmer-Engert, R., Landgraf, C., & Schneider-Mergener, J. (1994) Combinatorial cellulose-bound peptide libraries: Screening tools for the identification of peptides that bind ligands with predefined specifity. Methods: A Companion to Methods in Enzymology, 6, 388-395. #2208

  166. Krchnak, V., Cabel, D., Weichsel, A., & Flegelova, Z. (1994) Esterification of polymer-supported hydroxyl groups using the Mitsunobu reaction. Lett. Peptide Sci., 1, 277-282. #2427

  167. Krook, M., Mosbach, K., & Lindbladh, C. (1994) Selection of peptides with affinity for single stranded DNA using a phage display library. Biochem. Biophys. Res. Commun., 204, 849-854. #9299

  168. Kurth, M.J., Randall, L.A.A., Chen, C., Melander, C., Miller, R.B., McAlister, K., Reitz, G., Kang, R., Nakatsu, T., & Green, C. (1994) Library-based lead compound discovery: Antioxydants by an analogous synthesis deconvolutive assay strategy. J. Org. Chem., 59, 5862-5864. #1635

  169. Lam, K.S., & Lebl, M. (1994) Selectide technology: Bead-binding screening. Methods: A Companion to Methods in Enzymology, 6, 372-380. #762

  170. Lam, K.S., Lebl, M., Krchnak, V., Lake, D.F., Smith, J., Wade, S., Ferguson, R., Ackerman-Berrier, M. & Wertman, K. (1994) Application of Selectide technology in identifying (i) a mimotope for a discontinuous epitope, and (ii) D-amino acid ligands. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1003-1004). ESCOM, Leiden. #515

  171. Lam, K.S., Zhao, Z.G., Wade, S., Krchnak, V., & Lebl, M. (1994) Identification of small peptides that interact specifically with a small organic dye. Drug Develop. Res., 33, 157-160. #1009

  172. Lam, K.S., & Wu, J. (1994) Selectide technology: Substrate motif identification for post- translational modifications. Methods: A Companion to Methods in Enzymology, 6, 401-403. #759

  173. Lam, K.S., Lebl, M., Wade, S., Stierandova, A., Khattri, P.S., Collins, N. & Hruby, V.J. (1994) Streptavidin-peptide interaction as a model system for molecular recognition. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1005-1006). ESCOM, Leiden. #514

  174. Lasonder, E., Schellekens, G.A., & Welling, G.W. (1994) A fast and sensitive method for the evaluation of binding of phage clones selected from a surface displayed library. Nucl. Acid. Res., 22, 545-546. #926

  175. Latham, J.A., Johnson, R., & Toole, J.J. (1994) The application of a modified nucleotide in aptamer selection: Novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridine. Nucl. Acid. Res., 22, 2817-2822. #2563

  176. Leach, A.R. (1994) Ligand docking to proteins with discrete side-chain flexibility. J. Mol. Biol., 235, 345-356. #7002

  177. Lebl, M., Krchnak, V., Salmon, S.E., & Lam, K.S. (1994) Screening of completely random one-bead one-peptide libraries for activities in solution. Methods: A Companion to Methods in Enzymology, 6, 381-387. #755

  178. Lebl, M., Krchnak, V., Sepetov, N.F., Kocis, P., Patek, M., Flegelova, Z., Ferguson, R., & Lam, K.S. (1994) Synthetic combinatorial libraries. A new tool for drug design: Methods for identifying the composition of compound from peptide and/or nonpeptide libraries. J. Protein Chem., 13, 484-486. #1352

  179. Lebl, M., Krchnak, V., Stierandova, A., Safar, P., Kocis, P., Nikolaev, V., Sepetov, N.F., Ferguson, R., Seligmann, B., Lam, K.S. & Salmon, S.E. (1994) Nonsequenceable and/or nonpeptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1007-1008). ESCOM, Leiden. #513

  180. Lebl, M., Krchnak, V., Sepetov, N.F., Nikolaev, V., Stierandova, A., Safar, P., Seligmann, B., Strop, P., Thorpe, D., Felder, S., Lake, D.F., Lam, K.S. & Salmon, S.E. (1994) One bead-one structure libraries. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 233-238). Mayflower Worldwide Limited, Birmingham. #512

  181. Lebl, M., Krchnak, V., Safar, P., Stierandova, A., Sepetov, N.F., Kocis, P. & Lam, K.S. (1994) Construction and screening of libraries of peptide and non- peptide structures. In J.W. Crabb (Ed.), Techniques in Protein Chemistry V. (pp. 541-548). Academic Press, San Diego. #510

  182. Leclerc, F., Cedergren, R., & Ellington, A.D. (1994) A three-dimensional model of the Rev-binding element of HIV-1 derived from analyses of aptamers. Struct. Biology, 1, 293-300. #2364

  183. Liskamp, R.M.J. (1994) New compound libraries: Pseudobiopolymers and diversomers. Angew. Chem., 106, 661-664. #1630

  184. Liskamp, R.M.J. (1994) Opportunities for new chemical libraries. Unnatural biopolymers and diversomers. Angew. Chem. Int. Ed., 33, 633-636. #932

  185. Longman, R. (1994) R&D strategies: The promise of combinatorial chemistry. J. In Vivo Res., #8517

  186. Look, G.C., Holmes, C.P., Chinn, J.P., & Gallop, M.A. (1994) Methods for combinatorial organic synthesis: The use of fast 13C NMR analysis for gel phase reaction monitoring. J. Org. Chem., 59, 7588-7590. #2106

  187. Lorsch, J.R., & Szostak, J.W. (1994) In vitro selection of RNA aptamers specific for cyanocobalamin. Biochemistry, 33, 973-982. #2366

  188. Lowe, G. (1994) Targeted libraries of CMTI-1 mutants and the identification of potential serine proteinase inhibitors. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 377-380). Mayflower Worldwide Limited, Birmingham. #1867

  189. Lowe, G., & Quarrell, R. (1994) Screening peptide bead libraries for enzyme inhibitors. Methods: A Companion to Methods in Enzymology, 6, 411-416. #992

  190. Luo, G., An, G., & Wu, R. (1994) A PCR differential screening method for rapid isolation of clones from a cDNA library. BioTechniques, 16, 670-675. #785

  191. Lyttle, M.H., Berry, C.O.A., Villar, H.O., Hocker, M.H. & Kauvar, L.M. (1994) Novel concepts in the preparation and use of planar arrays of peptides with unnatural amino acids and cyclic structures. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1009-1011). ESCOM, Leiden. #1014

  192. Maeji, N.J., Valerio, R.M., Bray, A.M., Campbell, R.A., & Geysen, H.M. (1994) Grafted supports used with the multipin method of peptide synthesis. React. Polym., 22, 203-212. #2560

  193. Markiewicz, W.T., Adrych-Rozek, K., Markiewicz, M., Zebrowska, A. & Astriab, A. (1994) Synthesis of oligonucleotides permanently linked with solid supports for use as synthetic oligonucleotide combinatorial libraries. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 339-346). Mayflower Worldwide Limited, Birmingham. #1866

  194. Martin, F., Toniatti, C., Salvati, A.L., Venturini, S., Ciliberto, G., Cortese, R., & Sollazzo, M. (1994) The affinity-selection of a minibody polypeptide inhibitor of human interleukin-6. EMBO J., 13, 5303-5309. #2257

  195. Mattheakis, L.C., Bhatt, R.R., & Dower, W.J. (1994) An in vitro polysome display system for identifying ligands from very large peptide libraries. Proc. Natl. Acad. Sci. USA, 91, 9022-9026. #1940

  196. McConnell, S.J., Kendall, M.L., Reilly, T.M., & Hoess, R.H. (1994) Constrained peptide libraries as a tool for finding mimotopes. Gene, 151, 115-118. #2683

  197. Medynski, D. (1994) Synthetic peptide combinatorial libraries. Biotechnology, 12, 709-710. #1558

  198. Medynski, D. (1994) Phage display: All dressed-up and ready to role. Biotechnology, 12, 1134-1136. #1560

  199. Meldal, M. (1994) Multiple column synthesis of quenched solid-phase bound fluorogenic substrates for characterization of endoprotease specificity. Methods: A Companion to Methods in Enzymology, 6, 417-424. #993

  200. Meldal, M., Auzanneau, F.I. & Bock, K. (1994) PEGA, characterization and application of a new type of resin for peptide and glycopeptide synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 259-266). Mayflower Worldwide Limited, Birmingham. #1863

  201. Meldal, M., Svendsen, I., Breddam, K., & Auzanneau, F.I. (1994) Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity. Proc. Natl. Acad. Sci. USA, 91, 3314-3318. #771

  202. Metzger, J.W., Kempter, C., Wiesmuller, K.H., & Jung, G. (1994) Electrospray mass spectrometry and tandem mass spectrometry of synthetic multicomponent peptide mixtures: Determination of composition and purity. Anal. Biochem., 219, 261-277. #2611

  203. Metzger, J.W. (1994) Ladder seguencing of peptides and proteins.A combination of Edman degradation and mass spectrometry. Angew. Chem. Int. Ed., 33, 723-725. #994

  204. Metzger, J.W., Stevanovic, S., Brunjes, J., Wiesmuller, K.H., & Jung, G. (1994) Electrospray mass spectrometry and multiple sequence analysis of synthetic peptide libraries. Methods: A Companion to Methods in Enzymology, 6, 425-431. #2211

  205. Meulemans, E.V., Slobbe, R., Wasterval, P., Ramaekers, F.C.S., & van Eys, G.J.J.M. (1994) Selection of phage-displayed antibodies specific for a cytoskeletal antigen by competitive elution with a monoclonal antibody. J. Mol. Biol., 244, 353-360. #4709

  206. Miceli, R.M., DeGraaf, M.E., & Fischer, H.D. (1994) Two-stage selection of sequences from a random phage display library delineates both core residues and permitted structural range within an epitope. J. Immunol. Method, 167, 279-287. #930

  207. Mink, M.A., Benichou, S., Madaule, P., Tiollais, P., Prince, A.M., & Inchauspe, G. (1994) Characterization and mapping of a B-cell immunogenic domain in hepatitis C virus E2 glycoprotein using a yeast peptide library. Virology, 200, 246-255. #936

  208. Mitchell, L.A., Decarie, D., Tingle, A.J., Lacroix, M., & Zrein, M. (1994) Use of synthetic peptides to map regions of rubella virus capsid protein recognized by human T lymphocytes. Vaccine, 12, 639-645. #815

  209. Moos, W.H. (1994) Editorial: Biological and chemical diversity. Drug Develop. Res., 33, 63-63. #2698

  210. Morris, K.N., Tarasow, T.M., Julin, C.M., Simons, S.L., Hilvert, D., & Gold, L. (1994) Enrichment for RNA molecules that bind a Diels-Alder transition state analog. Proc. Natl. Acad. Sci. USA, 91, 13028-13032. #2138

  211. Motti, C., Nuzzo, M., Meola, A., Galfre, G., Felici, F., Cortese, R., Nicosia, A., & Monaci, P. (1994) Recognition by human sera and immunogenicity of HBsAg mimotopes selected from an M13 phage display library. Gene, 146, 191-198. #1951

  212. Muro, Y., Tsai, W.M., Houghten, R., & Tan, E.M. (1994) Synthetic combinatorial peptide simulating antigenicity of conformation-dependent autoepitope. Journal of Biological Chemistry, 269, 18529-18534. #8684

  213. Nestler, H.P., Bartlett, P.A., & Still, W.C. (1994) A general method for molecular tagging of encoded combinatorial chemistry libraries. J. Org. Chem., 59, 4723-4724. #1312

  214. Nielsen, J. (1994) Combinatorial chemistry. Chem. Ind. -London, 902-905. #2276

  215. Nielsen, J., & Janda, K.D. (1994) Towards chemical implementation of encoded combinatorial libraries. Methods: A Companion to Methods in Enzymology, 6, 361-371. #476

  216. Nielsen, T., Bell, D., Lamoureux, C., Zannishadjopoulos, M., & Price, G. (1994) A reproducible method for identification of human genomic DNA autonomously replicating sequences. Mol. Gen. Genet., 242, 280-288. #792

  217. Nissim, A., Hoogenboom, H.R., Tomlinson, I.M., Flynn, G., Midgley, C., Lane, D., & Winter, G. (1994) Antibody fragments from a 'single pot' phage display library as immunochemical reagents. EMBO J., 13, 692-698. #919

  218. Nokihara, K. (1994) Highly efficient peptide-synthesis: Automated simultaneous multiple solid-phase synthesis and peptide library. J. Syn. Org. Chem. Jpn., 52, 347-358. #2565

  219. O'Neil, K.T., DeGrado, W.F. & Hoess, R.H. (1994) Phage display of random peptides on a protein scaffold. In J.W. Crabb (Ed.), Techniques in Protein Chemistry V. (pp. 517-524). Academic Press, San Diego. #1036

  220. Orlandi, R., Menard, S., Colnaghi, M.I., Boyer, C.M., & Felici, F. (1994) Antigenic and immunogenic mimicry of the HER2/neu oncoprotein by phage-displayed peptides. Eur. J. Immunol., 24, 2868-2873. #4816

  221. Ostresh, J.M., Winkle, J.M., Hamashin, V.T., & Houghten, R.A. (1994) Peptide libraries: Determination of relative reaction rates of amino acids in competitive couplings. Biopolymers, 34, 1681-1689. #996

  222. Ostresh, J.M., Husar, G.M., Blondelle, S.E., Dorner, B., Weber, P.A., & Houghten, R.A. (1994) "Libraries from libraries": Chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity. Proc. Natl. Acad. Sci. USA, 91, 11138-11142. #1921

  223. Palzkill, T., Le, Q.Q., Wong, A., & Botstein, D. (1994) Selection of functional signal peptide cleavage sites from a library of random sequences. J. Bacteriol., 176, 563-568. #929

  224. Patek, M., Drake, B., & Lebl, M. (1994) All-cis cyclopentane scaffolding for combinatorial solid phase synthesis of small non-peptide compounds. Tetrahedron Lett., 35, 9169-9172. #1346

  225. Pease, A.C., Solas, D., Sullivan, E.J., Cronin, M.T., Holmes, C.P., & Fodor, S.P.A. (1994) Light-generated oligonucleotide arrays for rapid DNA sequence analysis. Proc. Natl. Acad. Sci. USA, 91, 5022-5026. #2154

  226. Pei, Y., & Moos, W.H. (1994) Post-modification of peptoid side chains: [3+2] Cycloaddition of nitrile oxides with alkenes and alkynes on the solid-phase. Tetrahedron Lett., 35, 5825-5828. #11601

  227. Pei, Y.H., & Moos, W.H. (1994) Post-modification of peptoid side chains: [3+2] cycloaddition of nitrile oxides with alkenes and alkynes on the solid-phase. Tetrahedron Lett., 35, 5825-5828. #217

  228. Pessi, A. (1994) Synthetic peptide combinatorial libraries: A journey through "shape space". Chim. Oggi, 12, 11-14. #618

  229. Pietu, G., Ribba, A.S., Cherel, G., Siguret, V., Obert, B., Rouault, C., Ginsburg, D., & Meyer, D. (1994) Epitope mapping of inhibitory monoclonal antibodies to human von Willebrand factor by using recombinant cDNA libraries. Thromb. Haemost., 71, 788-792. #5244

  230. Pinilla, C., Appel, J.R., & Houghten, R.A. (1994) Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic dacapeptide library composed of four trillion [4x10(12)] sequences. Biochem. J., 301, 847-853. #1306

  231. Pinilla, C., Appel, J.R. & Houghten, R.A. (1994) Identification of antigenic determinants using synthetic peptide combinatorial libraries. In J.E. Coligan, A.M. Kruisbeek, D.H. Margulies, E.M. Shevach & W. Strober (Eds.), Current Protocols in Immunology. (pp. 9.8.1-9.8.15. John Wiley & Sons,Inc., New York. #567

  232. Pinilla, C., Appel, J.R., Milich, D. & Houghten, R.A. (1994) Identification of an antigenic determinant for the surface antigen of hepatitis B virus using peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1016-1017). ESCOM, Leiden. #566

  233. Pinilla, C., Appel, J.R., Blondelle, S.E., Dooley, C.T., Eichler, J., Ostresh, J.M., & Houghten, R.A. (1994) Versatility of positional scanning synthetic combinatorial libraries for the identification of individual compounds. Drug Develop. Res., 33, 133-145. #1900

  234. Pirrung, M.C. (1994) "Analogous" organic synthesis of small-compound libraries: Validation of combinatorial chemistry in small-molecule synthesis. Chemtracts:Org. Chem., 7, 184-186. #1843

  235. Posner, B., Smiley, J., Lee, I., & Benkovic, S. (1994) Catalytic antibodies: Perusing combinatorial libraries. Trends Biochem. Sci., 19, 145-150. #787

  236. Prummel, M.F., Portolano, S., Costante, G., Rapoport, B., & McLachlan, S.M. (1994) Isolation and characterization of monoclonal human thyroid peroxidase autoantibody of lambda light chain type. Mol. Cell. Endocrinol., 102, 161-166. #4666

  237. Qi, J., Lu, Z., Wang, Y., & Li, W. (1994) Peptide library and its applications in molecular recognition [in Chinese]. Shengwu Huaxue Yu Shengwu Wuli Jinzhan, 21, 513-517. #2601

  238. Reece, J.C., McGregor, D.L., Geysen, H.M., & Rodda, S.J. (1994) Scanning for T helper epitopes with human PBMC using pools of short synthetic peptides. J. Immunol. Method, 172, 241-254. #5508

  239. Richter, L.S., & Gadek, T.R. (1994) A surprising observation about Mitsunobu reactions in solid phase synthesis. Tetrahedron Lett., 35, 4705-4706. #1097

  240. Rickles, R.J., Botfield, M.C., Weng, Z., Taylor, J.A., Green, O.M., Brugge, J.S., & Zoller, M.J. (1994) Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries. EMBO J., 13, 5598-5604. #2274

  241. Rose, K. (1994) Artificial proteins made by parallel assembly. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 21-28). Mayflower Worldwide Limited, Birmingham. #1853

  242. Rosenberg, M., Przybylska, M., & Straus, D. (1994) "RFLP substraction": A method for making libraries of polymorphic markers. Proc. Natl. Acad. Sci. USA, 91, 6113-6117. #5245

  243. Ruvo, M., Scardino, P., Cassani, G., & Fassina, G. (1994) Facile manual synthesis of peptide libraries. Protein Peptide Lett., 1, 187-192. #1840

  244. Salmon, S.E., Lam, K.S., Lebl, M., Kandola, A., Khattri, P.S., Healy, S., Wade, S., Patek, M., Kocis, P., Krchnak, V., Thorpe, D. & Felder, S. (1994) An orthogonal partial cleavage approach for solution-phase identification of biologically active peptides from larger chemically synthesized peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1001-1002). ESCOM, Leiden. #516

  245. Salmon, S.E., Lam, K.S., Felder, S., Yeoman, H., Schlessinger, J., Ullrich, A., Krchnak, V., & Lebl, M. (1994) One bead, one chemical compound: Use of the Selectide process for anticancer drug discovery. Acta Oncol., 33, 127-131. #1287

  246. Saneii, H.H., Shannon, J.D., Miceli, R.M., Fischer, H.D. & Smith, C.W. (1994) Comparison of the selection and hierarchical dominance of phage-derived or advanced ChemTech Model 357 chemically synthesized epitope to a monoclonal antibody specific for peptide flag immunogen. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 335-338). Mayflower Worldwide Limited, Birmingham. #751

  247. Saneii, H.H., Shannon, J.D., Miceli, R.M., Fischer, H.D. & Smith, C.W. (1994) Fully automated selection and synthesis of peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 1018-1020). ESCOM, Leiden. #1013

  248. Saneii, H.H., Shannon, J.D., Miceli, R.M., Fischer, H.D. & Smith, C.W. (1994) Comparison of a phage-derived peptide library with one synthesized chemically on the peptide librarian. In Y. Okada (Ed.), Peptide Chemistry 1993. (pp. 117-119). Protein Research Foundation, Osaka. #3373

  249. Sang, J., & Thompson, N.L. (1994) An efficient procedure for obtaining long cDNA clones from phage library screening. BioTechniques, 17, 446-451. #1941

  250. Schatz, P.J. (1994) Construction and screening of biological peptide libraries. Curr. Opin. Biotechnol., 5, 487-494. #995

  251. Schellekens, G.A., Lasonder, E., Feijlbrief, M., Koedijk, D.G.A.M., Drijfhout, J.W., Scheffer, A.J., Welling-Wester, S., & Welling, G.W. (1994) Identification of the core residues of the epitope of a monoclonal antibody raised against glycoprotein D of herpes simplex virus type 1 by screening of a random peptide library. Eur. J. Immunol., 24, 3188-3193. #2273

  252. Scott, J.K., & Craig, L. (1994) Random peptide libraries. Curr. Opin. Biotechnol., 5, 40-48. #1821

  253. Shao, W., & Pratt, K. (1994) Cloning genes for DNA binding proteins: Dot-blotting to optimize cDNA expression library screening. Anal. Biochem., 218, 465-468. #825

  254. Shepherd, N.S., Pfrogner, B.D., Coulby, J.N., Ackerman, S.L., Vaidyanathan, G., Sauer, R.H., Balkenhol, T.C., & Sternberg, N. (1994) Preparation and screening of an arrayed human genomic library generated with the P1 cloning system. Proc. Natl. Acad. Sci. USA, 91, 2629-2633. #791

  255. Shimizu, K.D., Cole, B.M., Krueger, C.A., Kuntz, K.W., Snapper, M.L., & Hoveyda, A.H. (1994) Search for chiral catalysts through ligand diversity: Substrate-specific catalysts and ligand screening on solid phase. Angew. Chem., 1703-1707. #10360

  256. Sidney, J., Oseroff, C., del Guercio, M.F., Southwood, S., Krieger, J.I., Ishioka, G.Y., Sakaguchi, K., Appella, E., & Sette, A. (1994) Definition of a DQ3.1: Specific binding motif. Journal of Immunology, 152, 4516-4525. #2617

  257. Simon, R.J., Martin, E.J., Miller, S.M., Zuckermann, R.N., Blaney, J.M. & Moos, W.H. (1994) Using peptoid libraries [oligo N-substituted glycines] for drug discovery. In J.W. Crabb (Ed.), Techniques in Protein Chemistry V. (pp. 533-539). Academic Press, San Diego. #1038

  258. Sinigaglia, F., & Hammer, J. (1994) Rules for peptide binding to MHC class II molecules. APMIS, 102, 241-248. #4817

  259. Siuzdak, G. (1994) The emergence of mass spectrometry in biochemical research. Proc. Natl. Acad. Sci. USA, 91, 11290-11297. #11663

  260. Slightom, J.L., Bock, J.H., Siemieniak, D.R., Hurst, G.D., & Beattie, K.L. (1994) Nucleotide sequencing double-stranded plasmids with primers selected from a nonamer library. BioTechniques, 17, 536-544. #1948

  261. Smith, M.H., Lam, K.S., Hersh, E.M., Lebl, M., & Grimes, W.J. (1994) Peptide sequences binding to MHC class I proteins. Mol. Immunol., 31, 1431-1437. #1007

  262. Smith, P.W., Lai, J.Y.Q., Whittington, A.R., Cox, B., & Houston, J.G. (1994) Synthesis and biological evaluation of a library containing potentially 1600 amides/esters.A strategy for rapid compound generation and screening. Bioorg. Med. Chem. Lett., 4, 2821-2824. #2801

  263. Songyang, Z., Blechner, S., Hoagland, N., Hoekstra, M.F., Piwnica-Worms, H., & Cantley, L.C. (1994) Use of an oriented peptide library to determine the optimal substrates of protein-kinases. Curr. Biol., 4, 973-982. #2676

  264. Southern, E.M., & Maskos, U. (1994) Parallel synthesis and analysis of large numbers of related chemical compounds: Applications to oligonucleotides. J. Biotechnol., 35, 217-227. #2597

  265. Sparks, A.B., Quilliam, L.A., Thorn, J.M., Der, C.J., & Kay, B.K. (1994) Identification and characterization of Src SH3 ligands from phage-displayed random peptide libraries. Journal of Biological Chemistry, 269, 23853-23856. #1938

  266. Stankova, M., Wade, S., Lam, K.S., & Lebl, M. (1994) Synthesis of combinatorial libraries with only one representation of each structure. Peptide Res., 7, 292-298. #1754

  267. Stankova, M., Issakova, O., Sepetov, N.F., Krchnak, V., Lam, K.S., & Lebl, M. (1994) Application of one-bead one-structure approach to identification of nonpeptidic ligands. Drug Develop. Res., 33, 146-156. #1008

  268. Stankovic, C.J., DeWitt, S.H., Schroeder, M.C., Kiely, J.S., Cody, D.M.R. & Pavia, M.R. (1994) Diversomer libraries a novel approach to chemical diversity. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 391-396). Mayflower Worldwide Limited, Birmingham. #1869

  269. Stevanovic, S., Gnau, V., Malcherek, G., Falk, K., Rotzschke, O., Rammensee, H.G., Melms, A. & Jung, G. (1994) Multiple sequence analysis of the natural peptide libraries bound to MHC I and MHC II molecules. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 327-334). Mayflower Worldwide Limited, Birmingham. #1865

  270. Strop, P. (1994) Synthetic combinatorial peptide libraries: A powerful tool for basic research and drug discovery. Methods: A Companion to Methods in Enzymology, 6, 351-353. #2207

  271. Sullivan, M. (1994) Mass screening: A new approach to chemical discovery. Today's Chemist at Work, 19-26. #1319

  272. Sun, Y., & Ball, W.J. (1994) Identification of antigenic sites on the Na+/K+-ATPase beta- subunit: Their sequences and the effects of thiol reduction upon their structure. Biochim. Biophys. Acta, 1207, 236-248. #2249

  273. Thomas, M.G., Hesse, S.A., Al-Mahdawi, S., Bui, T.D., Moniz, C.F., & Farzaneh, F. (1994) A procedure for second-round differential screening of cDNA libraries. BioTechniques, 16, 229-232. #793

  274. Thompson, L.A., & Ellman, J.A. (1994) Straightforward and general method for coupling alcohols to solid supports. Tetrahedron Lett., 35, 9333-9336. #2112

  275. Till, J.H., Annan, R.S., Carr, S.A., & Miller, W.T. (1994) Use of synthetic peptide libraries and phosphopeptide. Selective mass spectrometry to probe protein kinase substrate specificity. Journal of Biological Chemistry, 269, 7423-7428. #927

  276. Tizard, B.K., Stanton, J.A.L., & Laing, N.G. (1994) DiffScreen: The merging of image subtraction and molecular genetics for the rapid analysis of differentially screened cDNA libraries. Comput. Appl. Biosci., 10, 209-210. #841

  277. Traincard, F., Rey-Cuille, M.A., Huon, I., Dartevelle, S., Mazie, J.C., & Benichou, S. (1994) Characterization of monoclonal antibodies to human immunodeficiency virus type 2 envelope glycoproteins. AIDS Res. Hum. Retroviruses, 10, 1659-1667. #4735

  278. Tumelty, D., Vetter, D., & Antonenko, V.V. (1994) Immobilised, activated peptides as reagents for cyclic and derivatised peptide libraries. J. Chem. Soc. Chem. Commun., 1067-1068. #2134

  279. Turck, C.W. (1994) Radioactive screening of synthetic peptide libraries. Methods: A Companion to Methods in Enzymology, 6, 396-400. #2209

  280. Ullmann, D. & Jakubke, H.D. (1994) Solid phase synthesis of a peptide library for S'subsite mapping of serine and cysteine proteases. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 693-696). Mayflower Worldwide Limited, Birmingham. #769

  281. Vagner, J., Krchnak, V., Sepetov, N.F., Strop, P., Lam, K.S., Barany, G. & Lebl, M. (1994) Novel methodology for differentiation of "surface" and "interior" areas of poly(oxyethylene)-polystyrene (POE-PS) supports: Application to library screening procedures. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 347-352). Mayflower Worldwide Limited, Birmingham. #511

  282. Valerio, R.M., Bray, A.M., & Maeji, N.J. (1994) Multiple peptide synthesis on acid-labile handle derivatized polyethylene supports. Int. J. Peptide Prot. Res., 44, 158-165. #317

  283. van de Vanter, D.R., Choongkittaworn, N.M., Dyer, K.A., Aten, J., Otto, P., Behler, C., Bryant, E.M., & Rabinovitch, P.S. (1994) Pure chromosome-specific PCR libraries from single sorted chromosomes. Proc. Natl. Acad. Sci. USA, 91, 5858-5862. #5338

  284. Venturini, S., Martin, F., & Sollazzo, M. (1994) Phage display of the minibody: A b-scaffold for the selection of conformationally-constrained peptides. Protein Peptide Lett., 1, 70-75. #1048

  285. Virgilio, A.A., & Ellman, J.A. (1994) Simultaneous solid-phase synthesis of b-turn mimetics incorporating side-chain functionality. J. Amer. Chem. Soc., 116, 11580-11581. #2117

  286. Virnek s, B., Ge, L., Pluckthun, A., Schneider, K.C., Wellnhofer, G., & Moroney, S.E. (1994) Trinucleotide phosphoramidites: Ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis. Nucl. Acid. Res., 22, 5600-5607. #2018

  287. Vogel, M., Miescher, S., Biaggi, C., & Stadler, B.M. (1994) Human anti-IgE antibodies by repertoire cloning. Eur. J. Immunol., 24, 1200-1207. #4710

  288. Volkmer-Engert, R., Ernhard, B., Hellwig, J., Kramer, A., Hohne, W., & Schneider-Mergener, J. (1994) Preparation, analysis and antibody binding studies of simultaneously synthesized soluble and cellulose-bound HIV-1 p24 peptide epitope libraries. Lett. Peptide Sci., 1, 243-253. #3365

  289. Wallace, A., Altamura, S., Toniatti, C., Vitelli, A., Bianchi, E., Delmastro, P., Ciliberto, G., & Pessi, A. (1994) A multimeric synthetic peptide combinatorial library. Peptide Res., 7, 27-31. #768

  290. Wang, D. (1994) Solid phase simultaneous multiple peptide synthesis. Youji Huaxue, 14, 12-18. #2614

  291. Weber, L. (1994) Kombinatorische Chemie: Revolution in der Pharmaforschung? Nachr. Chem. Tech. Lab., 42, 698-702. #2432

  292. Weber, P., Blanc, P., Bloyer, R. & Houghten, R.A. (1994) Potent anti-herpes simplex virus type 1 activity of peptides identified through the use of a synthetic peptide combinatorial library. In J. Einhorn, C.R. Nord & S.R. Norrby (Eds.), Recent Advances in Chemotherapy. (pp. 649-650). American Society for Microbiology, Washington,D.C. #9381

  293. Wennemers, H., & Still, W.C. (1994) Peptide complexation in water. Sequence-selective binding with simple dye molecules. Tetrahedron Lett., 35, 6413-6416. #1354

  294. Wiesmuller, K.H., Beck-Sickinger, A.G., Ihlenfeldt, H.G., Wieland, H.A., Udaka, K., Walden, P. & Jung, G. (1994) Experimental limits of the peptide library concept. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 998-1000). ESCOM, Leiden. #1015

  295. Williamson, R.A., Burioni, R., Sanna, P.P., Partridge, L.J., Barbas, C.F.I., & Burton, D.R. (1994) Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries (Corrections of Vol 90, Pg 4141, 1993). Proc. Natl. Acad. Sci. USA, 91, 1193-1193. #958

  296. Winter, G., Griffiths, A.D., Hawkins, R.E., & Hoogenboom, H.R. (1994) Making antibodies by phage display technology. Annu. Rev. Immunol., 12, 433-455. #5246

  297. Winter, J. (1994) Bacteriophage display: Peptide libraries and drug discovery. Drug Develop. Res., 33, 71-89. #1894

  298. Wong, B.S., de Jong, P.J., & Batzer, M.A. (1994) A device to facilitate the manual manipulation of arrayed libraries. Anal. Biochem., 216, 237-239. #913

  299. Wong, W.Y., Sheth, H.B., Holm, A., Hodges, R.S., & Irvin, R.T. (1994) Representative combinatorial peptide libraries: An approach to reduce both synthesis and screening efforts. Methods: A Companion to Methods in Enzymology, 6, 404-410. #2210

  300. Wong, W.Y., Sheth, H.B., Holm, A., Irvin, R.T. & Hodges, R.S. (1994) Investigation of antibody binding diversity utilizing representative combinatorial peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 995-997). ESCOM, Leiden. #1017

  301. Wu, J., Ma, Q.N., & Lam, K.S. (1994) Identifying substrate motifs of protein kinases by a random library approach. Biochemistry, 33, 14825-14833. #1460

  302. Wyatt, J.R., Vickers, T.A., Roberson, J.L., Buckheit, R.W.J., Klimkait, T., DeBaets, E., Davis, P.W., Rayner, B., Imbach, J.L., & Ecker, D.J. (1994) Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proc. Natl. Acad. Sci. USA, 91, 1356-1360. #1962

  303. Yasuda, T., Nadano, D., Takeshita, H., & Kishi, K. (1994) Use of antibodies against synthetic peptides for analysis of molecular multiplicity: Human deoxyribonuclease I polymorphism. Electrophoresis, 15, 260-264. #937

  304. Yoon, S.S., & Still, W.C. (1994) Expeditious synthesis of a novel C(3)-symmetric receptor that binds peptides sequence-selectively. Angew. Chem. Int. Ed., 33, 2458-2460. #2680

  305. Yoon, S.S., & Still, W.C. (1994) Cyclooligomeric receptors for the sequence selective binding of peptides. A tetrahedral receptor from trimesic acid and 1,2-diamines. Tetrahedron Lett., 35, 8557-8560. #2609

  306. Young, J.K., Nelson, J.C., & Moore, J.S. (1994) Synthesis of sequence specific phenylacetylene oligomers on an insoluble solid support. J. Amer. Chem. Soc., 116, 10841-10842. #2037

  307. Youngquist, R.S., Fuentes, G.R., Lacey, M.P., & Keough, T. (1994) Matrix-assisted laser desorption ionization for rapid determination of the sequences of biologically active peptides isolated from support-bound combinatorial peptide libraries. Rapid Commun. Mass Spectrom., 8, 77-81. #770

  308. Yu, H., Chen, J.K., Feng, S., Dalgarno, D.C., Brauer, A.W., & Schreiber, S.L. (1994) Structural basis for the binding of proline-rich peptides to SH3 domains. Cell, 76, 933-945. #3442

  309. Yu, J.W., Qi, J.X., Tong, S.H., & Kao, F.T. (1994) A region-specific microdissection library for human chromosome 2P23-P25 and the analysis of an interstitial deletion of 2P23.3- P25.1. Hum. Genet., 93, 557-562. #861

  310. Yu, K.L., Deshpande, M.S., & Vyas, D.M. (1994) Heck reactions in solid phase synthesis. Tetrahedron Lett., 35, 8919-8922. #1308

  311. Zambias, R.A., Boulton, D.A., & Griffin, P.R. (1994) Microchemical structural determination of a peptoid covalently bound to a polymeric bead by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Tetrahedron Lett., 35, 4283-4286. #1096

  312. Zhang, W.J., Hortin, G.L., Panek, R.L., Lu, G.H., Hsu, F.F. & Marshall, G.R. (1994) A second dimension in complexity in combinatorial peptide libraries. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 978-980). ESCOM, Leiden. #1020

  313. Zhao, Y.M., & Chait, B.T. (1994) Protein epitope mapping by mass spectrometry. Anal. Chem., 66, 3723-3726. #8112

  314. Zhou, H., Fisher, R.J., & Papas, T.S. (1994) Optimization of primer sequences for mouse scFv repertoire display library construction. Nucl. Acid. Res., 22, 888-889. #924

  315. Zsigo, J. & Saneii, H.H. (1994) A facile, efficient method for the simultaneous synthesis of high-quality individual peptides: application of ACT model 350 for rapid multiple synthesis of peptides by solid phase method. In R.S. Hodges & J.A. Smith (Eds.), Peptides: Chemistry, Structure and Biology,Proc.13.APS. (pp. 91-92). ESCOM, Leiden. #500

  316. Zuckermann, R.N., Martin, E.J., Spellmeyer, D.C., Stauber, G.B., Shoemaker, K.R., Kerr, J.M., Figliozzi, G.M., Goff, D.A., Siani, M.A., Simon, R.J., Banville, S.C., Brown, E.G., Wang, L., Richter, L.S., & Moos, W.H. (1994) Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library. J. Med. Chem., 37, 2678-2685. #1171

  317. Zuckermann, R.N., Figliozzi, G.M., Banville, S.C., Kerr, J.M., Siani, M.A., Martin, E.J., Brown, E.G. & Wang, L. (1994) Automated tools for the production of non-natural molecular diversity. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis. (pp. 397-402). Mayflower Worldwide Limited, Birmingham. #1870

Monday, May 15, 2000