Papers on solid phase organic synthesis published in 1997

This list is arranged by the name of the first author. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (michal@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M., Leblova Z.: Dynamic database of references in molecular diversity. Internet http://www.5z.com.

Recently added entries are marked in bold

1. Anonymous. (1997) Non-traditional pathways of extraterrestrial formation of organic compounds. Russ. Chem. Bull., 46, 389-397. #9649

2. Akaji, K., & Kiso, Y. (1997) Macrocyclization on solid support using Heck reaction. Tetrahedron Lett., 38, 5185-5188. #9035

3. Alazzouzi, E., Escaja, N., Straub, M., Marti, B., Grandas, A., & Pedroso, E. (1997) A solid-phase method for the synthesis of small to medium-sized cyclic oligonucleotides. Nucleosides Nucleotides, 16, 1513-1514. #12504

4. Alazzouzi, E., Escaja, N., Grandas, A., & Pedroso, E. (1997) A straightforward solid-phase synthesis of cyclic oligodeoxyribonucleotides. Angew. Chem. Int. Ed., 36, 1506-1508. #12505

5. Altava, B., Burguete, M.I., Collado, M., Luis, S.V., Pozo, O., & Salvador, R.V. (1997) Preparation of polystyrene resins containing chiral groups derived from aminoacids. An. Quim., 93, 260-266. #10102

6. Altava, B., Burguete, M.I., Escuder, B., Luis, S.V., & Salvador, R.V. (1997) Polymer-grafted Ti-TADDOL complexes. Preparation and use as catalysts in Diel-Alder reactions. J. Org. Chem., 62, 3126-3134. #10891

7. Armstrong, R.W., Brown, S.D., Keating, T.A. & Tempest, P.A. (1997) Combinatorial synthesis exploiting multiple-component condensations, microchip encoding, and resin capture. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 153-190). John Wiley & Sons,Inc., New York. #8357

8. Arsequell, G., & Valencia, G. (1997) O-glycosyl alpha-amino acids as building blocks for glycopeptide synthesis. Tetrahedron:Asymmetry, 8, 2839-2876. #10104

9. Arterburn, J.B., & Perry, M.C. (1997) Rhenium catalyzed sulfurization of phosphorus(iii) compounds with thiiranes: New reagents for phosphorothioate ester synthesis. Tetrahedron Lett., 38, 7701-7704. #10105

10. Arumugam, V., Routledge, A., Abell, C., & Balasubramanian, S. (1997) Synthesis of 2-oxindole derivatives via the intramolecular Heck reaction on solid support. Tetrahedron Lett., 38, 6473-6476. #9321

11. Arya, P., & Ben, R.N. (1997) Combinatorial chemistry for the synthesis of carbohydrate libraries. Angew. Chem. Int. Ed., 36, 1280-1282. #9481

12. Athanassopoulos, P., Barlos, K., Gatos, D., Eleftheriou, S., Papaphotiou, G., & Tzavara, C. (1997) Application of resins of the trityl type in solid phase organic synthesis. Epitheor. Klin. Farmacol. Farmakokinet. ,Int. Ed., 11, 122-124. #10530

13. Babiak, J. Transforming your robotics into an infrastructure for the future. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.35 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8282

14. Backes, B.J., & Ellman, J.A. (1997) Solid support linker strategies. Curr. Opin. Chem. Biol., 1, 86-93. #8746

15. Baldwin, J.J. & Dolle, R. (1997) Deconvolution tools for solid-phase synthesis. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 153-174). American Chemical Society, Washington,DC. #11698

16. Baldwin, J.J. & Dolle, R.E. (1997) Deconvolution methods in solid-phase synthesis. In W.H. Moos, M.R. Pavia, B.K. Kay & A.D. Ellington (Eds.), Annual Reports in Combinatorial Chemistry and Molecular Diversity. (pp. 287-297). ESCOM, Leiden. #8629

17. Bankaitis-Davis, D., Huang, L., Koga, T., & Beaton, G. (1997) Oligonucleotide phosphonates: Solid phase synthesis and biochemical characterization. Nucleosides Nucleotides, 16, 945-949. #10111

18. Banville, S. C. and Zuckermann, R. N. Accelerating drug discovery by high-throughput combinatorial synthesis. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.77 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8285

19. Barany, G., Albericio, F., Kates, S.A., & Kempe, M. (1997) Poly(ethylene glycol)-containing supports for solid-phase synthesis of peptides and combinatorial organic libraries. ACS Symp. Ser., 680, 239-264. #9612

20. Barany, G. & Kempe, M. (1997) The contex of solid-phase synthesis. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 51-97). American Chemical Society, Washington,DC. #11696

21. Barany, G., Albericio, F., Kates, S.A., & Kempe, M. (1997) Polyethylene glycol-containing supports for solid phase synthesis of peptides and combinatorial organic libraries. Polym. Preprint., 38, 587-588. #8520

22. Barber-Peoch, I., Manoharan, M., & Cook, P.D. (1997) Solid phase conjugation chemistry: Use of alloc as a protecting group for 2'-aminolinker containing oligonucleotides. Nucleosides Nucleotides, 16, 1407-1410. #12506

23. Barcelo, D., & Alpendurada, M.F. (1997) Automated online solid-phase extraction methods in interlaboratory studies of polar pesticides in water samples. Lab. Robotics Automation, 9, 165-174. #9327

24. Bauer, U., Ho, W.B., & Koskinen, A.M.P. (1997) A novel linkage for the solid-phase synthesis of hydroxamic acids. Tetrahedron Lett., 38, 7233-7236. #9563

25. Baxter, A.D. (1997) Synthesis utilizing insoluble polymers: New reactions and small molecules. Curr. Opin. Chem. Biol., 1, 79-85. #8739

26. Bellon, L., Workman, C.T., Jarvis, T.C., & Wincott, F.E. (1997) Post-synthetically ligated ribozymes: An alternative approach to iterative solid-phase synthesis. Bioconjug. Chem., 8, 204-212. #9275

27. Beltrßn, M., Maseda, M., Perez, Y., Robles, J., Pedroso, E., & Grandas, A. (1997) Stepwise solid-phase synthesis of serine-, tyrosine- and homoserine-nucleopeptides. Nucleosides Nucleotides, 16, 1487-1488. #10115

28. Bernhardt, A., Drewello, M., & Schutkowski, M. (1997) The solid-phase synthesis of side-chain-phosphorylated peptide-4-nitroanilides. J. Pept. Res., 50, 143-152. #9410

29. Bhalay, G., Blaney, P., Palmer, V.H., & Baxter, A.D. (1997) Solid-phase synthesis of diverse tetrahydro-1,4-benzodiazepine-2-ones. Tetrahedron Lett., 38, 8375-8378. #9674

30. Bharathi, P., & Moore, J.S. (1997) Solid-supported hyperbranched polymerization: Evidence for self-limited growth. J. Amer. Chem. Soc., 119, 3391. #14284 NEWOLD

31. Bitan, G., Sukhotinsky, I., Mashriki, Y., Hanani, M., Selinger, Z., & Gilon, C. (1997) Synthesis and biological activity of novel backbone-bicyclic substance-P analogs containing lactam and disulfide bridges. J. Pept. Res., 49, 421-426. #9198

32. Blackburn, C., Albericio, F., & Kates, S.A. (1997) Functionalized resins and linkers for solid-phase synthesis of small molecules. Drugs Future, 22, 1007-1025. #9840

33. Blixt, O., & Norberg, T. (1997) Solid-phase enzymatic synthesis of a Lewis a trisaccharide using an acceptor reversibly bound to sepharose. J. Carbohyd. Chem., 16, 143-154. #12507

34. Bolton, G.L., Hodges, J.C., & Rubin, J.R. (1997) Solid phase synthesis of fused bicyclic amino acid derivatives via intramolecular Pauson-Khand cyclization: Versatile scaffolds for combinatorial chemistry. Tetrahedron, 53, 6611-6634. #8636

35. Boojamra, C.G., Burow, K.M., Thompson, L.A., & Ellman, J.A. (1997) Solid-phase synthesis of 1,4-benzodiazepine-2,5-diones. Library preparation and demonstration of synthesis generality. J. Org. Chem., 62, 1240-1256. #8522

36. Boymel, J. L., Goodman, B., Johnson, C., Governski, B., Ross-Kramer, J., Van Ausdall, D. A., Jones, T., and Marshall, W. S. Data management in the oligonucleotide synthesis laboratory. A case study in evolution. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.177 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8302

37. Braich, R.S., & Damha, M.J. (1997) Regiospecific solid-phase synthesis of branched oligonucleotides: Effect of vicinal 2',5'- (or 2',3'-) and 3',5'-phosphodiester linkages on the formation of hairpin DNA. Bioconjug. Chem., 8, 370-377. #9207

38. Brickmann, K., Somfai, P., & Kihlberg, J. (1997) An approach to enantiomerically pure inverse gamma-turn mimetics for use in solid-phase synthesis. Tetrahedron Lett., 38, 3651-3654. #8851

39. Briggs, J.C., Hodge, P., & Zhengpu, Z. (1997) Potassium borohydride reductions of immobilised ketosteroids. Tetrahedron, 53, 3943-3956. #12116

40. Bristol, J.A. (1997) Applications of solid-supported organic synthesis in combinatorial chemistry: Preface. Tetrahedron, 53, xiii-xiii. #9112

41. Brown, A.R., Rees, D.C., Rankovic, Z., & Morphy, J.R. (1997) Synthesis of tertiary amines using a polystyrene (REM) resin. J. Amer. Chem. Soc., 119, 3288-3295. #9152

42. Brown, D. (1997) Future pathways for combinatorial chemistry. Mol. Diversity, 2, 217-222. #8869

43. Brown, E.G., & Nuss, J.M. (1997) Alkylation of Rink's amide linker on polystyrene resin: A reductive amination approach to modified amine-linkers for the solid phase synthesis of N-substituted amide derivatives. Tetrahedron Lett., 38, 8457-8460. #9691

44. Brown, P.J., Hurley, K.P., Stuart, L.W., & Willson, T.M. (1997) Generation of secondary alkyl amines on solid support by borane reduction: Application to the parallel synthesis of PPAR ligands. Synthesis-Stuttgart, 778-782. #9411

45. Bruno, J.G., Chang, M.N., Choisledeski, Y.M., Green, D.M., Mcgarry, D.G., Regan, J.R., & Volz, F.A. (1997) Synthesis of functionalized aromatic oligomers from a versatile diphenylmethane template. J. Org. Chem., 62, 5174-5190. #9441

46. Bunin, B.A., Plunkett, M.J., Ellman, J.A., & Bray, A.M. (1997) The synthesis of a 1680 member 1,4-benzodiazepine library. New J. Chem., 21, 125-130. #9068

47. Burgess, K., Ibarzo, J., Linthicum, D.S., Russell, D.H., Shin, H., Shitangkoon, A., Totani, R., & Zhang, A.J. (1997) Solid phase syntheses of oligoureas. J. Amer. Chem. Soc., 119, 1556-1564. #8395

48. Burgess, K., Martinez, C.I., Russell, D.H., Shin, H., & Zhang, A.J. (1997) Photolytic mass laddering for fast characterization of oligomers on single resin beads. J. Org. Chem., 62, 5662-5663. #12508

49. Burgess, K., & Lim, D. (1997) Resin type can have important effects on solid phase asymmetric alkylation reactions. J. Chem. Soc. Chem. Commun., 785-786. #10890

50. Burgess, K., Lim, D., Bois-Choussy, M., & Zhu, J. (1997) Rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds. Tetrahedron Lett., 38, 3345-3348. #8804

51. Byk, G., Frederic, M., & Scherman, D. (1997) One pot synthesis of unsymetrically functionalized polyamines by a solid phase startegy starting from their symmetrical polyamine-counterparts. Tetrahedron Lett., 38, 3219-3222. #8798

52. Byrgesen, E., Nielsen, J., Willert, M., & Bols, M. (1997) Combinatorial chemistry of piperidine based carbohydrate mimics. Tetrahedron Lett., 38, 5697-5700. #9412

53. Campbell, J. B. and Wildonger, R. A. Managing compound library production by parallel synthesis on automated workstation-based systems. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.127 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8294

54. Cao, L.Q., Fischer, A., Bornscheuer, U.T., & Schmid, R.D. (1997) Lipase-catalyzed solid phase synthesis of sugar fatty acid esters. Biocatalysis and Biotransformation, 14, 269-283. #9281

55. Cargill, J.F., & Lebl, M. (1997) New methods in combinatorial chemistry: Robotics and parallel synthesis. Curr. Opin. Chem. Biol., 1, 67-71. #8737

56. Carlton, R.A., Orton, E., Lyman, C.E., & Roberts, J.E. (1997) Qualitative analysis of solid phase synthesis reaction products by X-ray spectrometry. Microscopy & Microanalysis, 3, 520-529. #10134

57. Carrasco, M.R., Fitzgerald, M.C., Oda, Y., & Kent, S.B.H. (1997) Direct monitoring of organic reactions on polymeric supports. Tetrahedron Lett., 38, 6331-6334. #9318

58. Catalanotti, B., Galeone, A., Mayol, L., Pepe, A., & Lanzotti, V. (1997) Synthetic polynucleotides and analogues as models for studies concerning DNA. Gazz. Chim. Ital., 127, 231-246. #10136

59. Caycho, J.R., Garcia-Tellado, F., de Armas, P., & Marrero-Tellado, J.J. (1997) Design and synthesis of a new tricyclic scaffold for molecular recognition. Tetrahedron Lett., 38, 7911-7912. #9655

60. Chaga, G.S., Guzman, R., & Porath, J.O. (1997) A new method of synthesizing biopolymeric affinity ligands. Biotechnol. Appl. Biochem., 26, 7-14. #9430

61. Chambers, S.L., Ronald, R., Hanesworth, J.M., Kinder, D.H., & Harding, J.W. (1997) Solid-phase synthesis of hydroxyethylamine angiotensin analogues. Peptides, 18, 505-512. #9517

62. Chan, T.Y., Chen, R., Sofia, M.J., Smith, B.C., & Glennon, D. (1997) High throughput on-bead monitoring of solid phase reactions by Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS). Tetrahedron Lett., 38, 2821-2824. #8786

63. Chen, C., Ahlberg Randall, L.A., Miller, R.B., Jones, A.D., & Kurth, M.J. (1997) The solid-phase combinatorial synthesis of beta-thioketones. Tetrahedron, 53, 6595-6609. #8637

64. Chen, S., & Janda, K.D. (1997) Synthesis of prostaglandin E2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries. J. Amer. Chem. Soc., 119, 8724-8725. #10139

65. Cheng, Y., & Chapman, K.T. (1997) Solid phase synthesis of spiroindoline. Tetrahedron Lett., 38, 1497-1500. #8373

66. Chin, J., Fell, B., Shapiro, M.J., Tomesch, J., Wareing, J.R., & Bray, A.M. (1997) Magic angle spinning NMR for reaction monitoring and structure determination of molecules attached to multipin crowns. J. Org. Chem., 62, 538-539. #8405

67. Cho, Y.R., Entress, R.M.H., & Williams, D.H. (1997) Synthesis of cell-wall analogues of vancomycin-resistant enterococci using solid phase peptide synthesis. Tetrahedron Lett., 38, 5229-5232. #9036

68. Claffey, D.J., & Ruth, J.A. (1997) Solid phase synthesis of (R)- and (S)-[(13)C]-butadiene monoxide. Tetrahedron:Asymmetry, 8, 3715-3716. #10144

69. Cohen, G., Deutsch, J., Fineberg, J., & Levine, A. (1997) Covalent attachment of dna oligonucleotides to glass. Nucl. Acid. Res., 25, 911-912. #8385

70. Collini, M.D., & Ellingboe, J.W. (1997) The solid phase synthesis of tri-substituted indoles. Tetrahedron Lett., 38, 7963-7966. #9615

71. Conti, P., Demont, D., Cals, J., Ottenheijm, H.C.J., & Leysen, D. (1997) A new cleavage strategy for the solid-phase synthesis of secondary amines. Tetrahedron Lett., 38, 2915-2918. #8789

72. Corbett, J.W., Graciani, N.R., Mousa, S.A., & DeGrado, W.F. (1997) Solid-phase synthesis of a selective alpha(v)beta(3) integrin antagonist library. Bioorg. Med. Chem. Lett., 7, 1371-1376. #9183

73. Corey, D.R. (1997) Peptide nucleic acids: Expanding the scope of nucleic acid recognition. Trends Biotech., 15, 224-229. #9192

74. Cowley, P.M., & Rees, D.C. (1997) Applications of solid-phase synthesis to drug discovery. Curr. Med. Chem., 4, 211-227. #11243

75. Crawshaw, M., Hird, N.W., Irie, K., & Nagai, K. (1997) Synthesis of 3,4,5-trisubstituted cyclohexanones by cycloaddition to solid phase 2-aminobutadienes. Tetrahedron Lett., 38, 7115-7118. #9578

76. Cuny, G.D., Cao, J., & Hauske, J.R. (1997) Ring opening cross-metathesis on solid support. Tetrahedron Lett., 38, 5237-5240. #9051

77. Czarnik, A.W. (1997) Encoding strategies in combinatorial chemistry. Proc. Natl. Acad. Sci. USA, 94, 12738-12739. #9883

78. Dankwardt, S.M., Smith, D.B., Porco, J.A.Jr., & Nguyen, C.H. (1997) Solid-phase synthesis of N-alkyl sulfonamides. Synlett, 854-856. #9523

79. Deben, I.E.A., Vanwijk, T.H.M., Vandoornum, E.M., Hermkens, P.H.H., & Kellenbach, E.R. (1997) Characterization of reaction products on solid supports by FT-IR. Mikrochim. Acta, 245-246. #9132

80. Debenham, J., Rodebaugh, R., & Fraser-Reid, B. (1997) Recent advances in N-protection for amino sugar synthesis. Liebigs Ann. Chem., 791-802. #13784

81. Deegan, T., MacDonald, A., Munyak, E., Wright, P., and Porco, J. A. Jr. Solid-phase synthesis of biaryls: Utilization of palladium catalysts on the Quest(TM) 210 manual synthesizer. 1997. #12547

82. Deegan, T.L., Gooding, O.W., Baudart, S., & Porco, J.A.Jr. (1997) Non-acidic cleavage of a Wang-derived ethers from solid support: Utilization of a mixed-bed scavenger for DDQ. Tetrahedron Lett., 38, 4973-4976. #9041

83. Del Nery, E., Juliano, M.A., Meldal, M., Svendsen, I., Scharfstein, J., Walmsley, A., & Juliano, L. (1997) Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides. Biochem. J., 323, 427-433. #9248

84. Dell'Aquila, C., Imbach, J.L., & Rayner, B. (1997) Photolabile linker for the solid-phase synthesis of base-sensitive oligonucleotides. Tetrahedron Lett., 38, 5289-5292. #9052

85. Denapoli, L., Messere, A., Montesarchio, D., Pepe, A., Piccialli, G., & Varra, M. (1997) Synthesis and triple helix formation by alternate strand recognition of oligonucleotides containing 3'-3' phosphodiester bonds. J. Org. Chem., 62, 9024-9030. #10156

86. DeWitt, S.H. & Czarnik, A.W. (1997) Parallel organic synthesis using Parke-Davis Diversomer method. In J.P. Devlin (Ed.), High Throughput Screening: The Discovery of Bioactive Substances. (pp. 191-208). Marcel Dekker,Inc., New York. #8994

87. DeWitt, S.H. & Czarnik, A.W. (1997) Parallel organic synthesis using Parke-Davis Diversomer technology. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 25-38). John Wiley & Sons,Inc., New York. #8351

88. Drewry, D.H., Gerritz, S.W., & Linn, J.A. (1997) Solid-phase synthesis of trisubstituted guanidines. Tetrahedron Lett., 38, 3377-3380. #8812

89. Drouillat, B., Kellam, B., Dekany, G., Starr, M.S., & Toth, I. (1997) Solid phase synthesis of C-terminal carbohydrate modified enkephalins. Bioorg. Med. Chem. Lett., 7, 2247-2250. #9986

90. Du, X., & Armstrong, R. (1997) Synthesis of benzofuran derivatives on solid support via SmI2-mediated radical cyclization. J. Org. Chem., 62, 5678-5679. #10889

91. Dunayevskiy, Y.M., Lai, J.J., Quinn, C., Talley, F., & Vouros, P. (1997) Mass spectrometric identifications of ligands selected from combinatorial libraries using gel filtration. Rapid Commun. Mass Spectrom., 11, 1178-1184. #9524

92. Ede, N.J., & Bray, A.M. (1997) A simple linker for the attachment of aldehydes to the solid phase. Application to solid phase synthesis by the Multipin(TM) method. Tetrahedron Lett., 38, 7119-7122. #9579

93. Egner, B.J., & Bradley, M. (1997) Analytical techniques for solid-phase organic and combinatorial synthesis. Drug Disc. Today, 2, 102-109. #8656

94. Egner, B.J., Rana, S., Smith, H., Bouloc, N., Frey, J., Brocklesby, W.S., & Bradley, M. (1997) Tagging in combinatorial chemistry: The use of colored and fluorescent beads. Chem. Commun., 735-736. #8727

95. Elofsson, M., Salvador, L.A., & Kihlberg, J. (1997) Preparation of Tn and sialyl Tn building blocks used in Fmoc solid-phase synthesis of glycopeptide fragments from HIV gp120. Tetrahedron, 53, 369-390. #12511

96. Epton, R. (1997) Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. Mayflower Scientific Limited, Birmingham. ISBN 0952701111 #8773

97. Esser, C.K., Kevin, N.J., Yates, N.A., & Chapman, K.T. (1997) Solid-phase synthesis of a N-carboxyalkyl tripeptide combinatorial library. Bioorg. Med. Chem. Lett., 7, 2639-2644. #9624

98. Fagnola, M.C., Candiani, I., Visentin, G., Cabri, W., Zarini, F., Mongelli, N., & Bedeschi, A. (1997) Solid-phase synthesis of indoles using the palladium-catalyzed coupling of alkynes with iodoaniline derivatives. Tetrahedron Lett., 38, 2307-2310. #8775

99. Fancelli, D., Fagnola, M.C., Severino, D., & Bedeschi, A. (1997) Solid phase synthesis of 2-substituted benzofurans via the palladium-catalyzed heteroannulation of acetylenes. Tetrahedron Lett., 38, 2311-2314. #8776

100. Fathi, R., Patel, R., & Cook, A.F. (1997) Phosphorus-based combinatorial libraries: Use of amino acid derivatives as synthons. Mol. Diversity, 2, 125-134. #8527

101. Fauchere, J.L., Henlin, J.M., & Boutin, J.A. (1997) Combinatorial chemistry: State-of -art, analytical needs and future evolutions [Review] [French]. Analusis, 25, 97-101. #9534

102. Fehrentz, J.A., Paris, M., Heitz, A., Velek, J., Winternitz, F., & Martinez, J. (1997) Solid phase synthesis of C-terminal peptide aldehydes. J. Org. Chem., 62, 6792-6796. #10172

103. Felder, S. Strategies for automated microplate synthesis of combinatorial libraries. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.124 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8292

104. Fensholdt, J., & Wengel, J. (1997) Synthesis of diastereomeric mixtures of 5'-C-hydroxymethylthymidine and introduction of a novel class of C-hydroxymethyl functionalised oligodeoxynucleotides. Acta Chem. Scand., 50, 1157-1163. #9374

105. Fitch, W.L., Szardenings, A.K., & Fujinari, E.M. (1997) Chemiluminescent nitrogen detection for HPLC: An important new tool in organic analytical chemistry. Tetrahedron Lett., 38, 1689-1692. #8459

106. Fitzpatrick, L.J., & Rivero, R.A. (1997) Solid phase synthesis of substituted aminosulfonyl ureas using a sulfonyl carbamate linker. Tetrahedron Lett., 38, 7479-7482. #9567

107. Fivush, A.M., & Willson, T.M. (1997) AMEBA: An acid sensitive aldehyde resin for solid phase synthesis. Tetrahedron Lett., 38, 7151-7154. #9559

108. Floyd, C., Lewis, C., Patel, S., and Whittaker, M. The automated synthesis of organic compounds. Some newcomers have some success. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.51 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8270

109. Fodor, S.P.A. (1997) Massively parallel biochemical assays. Lab. Automat. New., 2, 50-51. #9965

110. Fournout, S., Jouin, P., Pau, B., & Hanin, V. (1997) Comparison of different immunoenzymatic methods for the determination of the fine specificity and affinity constants of polyclonal antibodies against pseudopeptide haptens. Immunol. Invest., 26, 549-559. #10176

111. Fraley, M.E., & Rubino, R.S. (1997) Two methods for the preparation of 2-cyclohexenones from resin-bound 1,3-cyclohexanedione. Tetrahedron Lett., 38, 3365-3368. #8810

112. Franzyk, H., Christensen, M.K., Jorgensen, R.M., Meldal, M., Cordes, H., Mouritsen, S., & Bock, K. (1997) Constrained glycopeptide ligands for MPRs. Limitations of unprotected phosphorylated building blocks. Bioorg. Med. Chem., 5, 21-40. #9947

113. Fujii, M., Yoshida, K., & Hidaka, J. (1997) Nucleic acid analog peptide (NAAP). 2. Syntheses and properties of novel DNA analog peptides containing nucleobase linked beta-aminoalanine. Bioorg. Med. Chem. Lett., 7, 637-640. #10023

114. Fukase, K. (1997) Combinatorial chemistry [japanese]. J. Syn. Org. Chem. Jpn., 55, 474-479. #9108

115. Fukase, K., Egusa, K., Nakai, Y., & Kusumoto, S. (1997) Novel oxidatively removable protecting groups and linkers for solid-phase synthesis of oligosaccharides. Mol. Diversity, 2, 182-188. #8865

116. Furet, P., Gay, B., Garcia-Echeverria, C., Rahuel, J., Fretz, H., Schoepfer, J., & Caravatti, G. (1997) Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain. J. Med. Chem., 40, 3551-3556. #10178

117. Furth, P.S., Reitman, M.S., & Cook, A.F. (1997) A novel formamidine linker for use in solid-phase synthesis. Tetrahedron Lett., 38, 5403-5406. #9431

118. Furth, P.S., Reitman, M.S., Gentles, R., & Cook, A.F. (1997) Solid-phase synthesis of novel amino-ether derivatives. Tetrahedron Lett., 38, 6643-6646. #9546

119. Galarneau, E., & Gehr, R. (1997) Phosphorus removal from wastewaters: Experimental and theoretical support for alternative mechanisms. Water Res., 31, 328-338. #8464

120. Galeotti, N., Giraud, M., & Jouin, P. (1997) Solid phase synthesis of peptidyl aldehydes from C-terminal thiazolidinyl peptides. Lett. Peptide Sci., 4, 437-440. #14441

121. Gallop, M.A., & Fitch, W.L. (1997) New methods for analyzing compounds on polymeric supports. Curr. Opin. Chem. Biol., 1, 94-100. #8753

122. Gani, D., Akhtar, M., Kroll, F.E., Smith, C.F., & Stones, D. (1997) Permutational organic synthesis in addressable microreactors (POSAMT): An efficient, inexpensive and versatile solid-phase protocol for the preparation of libraries of compounds on the 0.01 to 1.0 millimole (or larger) scale. Tetrahedron Lett., 38, 8577-8580. #9580

123. Garcia-Echeverria, C. (1997) A base labile handle for solid phase organic chemistry. Tetrahedron Lett., 38, 8933-8934. #9860

124. Garcia-Echeverria, C., Husken, D., Schmit-Chiesi, C., & Altmann, K.H. (1997) Novel polyamide based nucleic acid analogs: Synthesis of oligomers and RNA-binding properties. Bioorg. Med. Chem. Lett., 7, 1123-1126. #10028

125. Garigipati, R.S. (1997) Reagents for combinatorial organic synthesis: Preparation and uses of Rink-chloride. Tetrahedron Lett., 38, 6807-6810. #9547

126. Gayo, L.M., & Suto, M.J. (1997) Traceless linker: Oxidative activation and displacement of a sulfur-based linker. Tetrahedron Lett., 38, 211-214. #8535

127. Gaytan, P., Yanez, J., Soberon, X., & Martinez, R. (1997) A new method for oligonucleotide derivatization of the 3' or 5'-termini with a CPG-support carrying the natural product isoargentatin-D. Tetrahedron Lett., 38, 6123-6126. #9311

128. Gennari, C., Nestler, H.P., Piarulli, U., & Salom, B. (1997) Combinatorial libraries: Studies in molecular recognition and the quest for new catalysts. Liebigs Ann. Chem., 637-647. #8665

129. Giorgetti-Peraldi, S., Ottinger, E., Wolf, G., Ye, B., Burke, T.R., & Shoelson, S.E. (1997) Cellular effects of phosphotyrosine-binding domain inhibitors on insulin receptor signaling and trafficking. Mol. Cell. Biol., 17, 1180-1188. #8393

130. Girdwood, J.A., & Shute, R.E. (1997) Solid-phase synthesis of tri-functionalised, alpha-substituted carbamoylmethyl-homocysteine compounds, their release from the resin and subsequent intramolecular cyclisation to give novel 1,3,3-trisubstituted succinimides. Chem. Commun., 2307-2308. #10189

131. Gohda, K., Matsuo, N., Oda, Y., Ikehara, M., & Uesugi, S. (1997) Effects of 2'-substituents of the first deoxyguanosine residue in the recognition sequence on ecori restriction endonuclease activity. J. Biochem. Tokyo, 121, 219-224. #8401

132. Good, L., & Nielsen, P.E. (1997) Progress in developing PNA as a gene-targeted drug [review]. Antisense Nucl. Acid Drug Devel., 7, 431-437. #10192

133. Goodman, B., Boymel, J., Johnson, C., Governski, B., Ross-Kramer, J., Van Ausdall, D., Jones, T., and Marshall, W. S. Automation in the oligonucleotide synthesis lab. The workstation approach. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.125 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8293

134. Goodman, B. A., Bjergarde, K., and Boymel, J. L. Developing a high speed synthesis paradigm the work station approach. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.142 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8296

135. Gopalsamy, A., & Pallai, P.V. (1997) Combinatorial synthesis of heterocycles: Solid phase synthesis of 2-arylquinoline-4-carboxylic acid derivatives. Tetrahedron Lett., 38, 907-910. #8406

136. Gordeev, M.F., Gordon, E.M., & Patel, D.V. (1997) Solid-phase synthesis of beta-sultams. J. Org. Chem., 62, 8177-8181. #9625

137. Gordeev, M.F., Hui, H.C., Gordon, E.M., & Patel, D.V. (1997) A general and efficient solid phase synthesis of quinazoline-2,4-diones. Tetrahedron Lett., 38, 1729-1732. #8458

138. Gordon, E.M., Patel, D.V., Jacobs, J.W., Gordeev, M.F., & Zhou, J. (1997) Strategy and tactics in combinatorial organic synthesis. Applications to drug discovery. Chimia, 51, 821-825. #9613

139. Gowravaram, M.R., & Gallop, M.A. (1997) "Traceless" solid-phase synthesis of furans via 1,3-dipolar cycloaddition reactions of isom nchones. Tetrahedron Lett., 38, 6973-6976. #9575

140. Gray, N.S., Kwon, S., & Schultz, P.G. (1997) Combinatorial synthesis of 2,9-substituted purines. Tetrahedron Lett., 38, 1161-1164. #8443

141. Green, C. The creation of an integrated data handling system for automated organic synthesis. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.164 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8298

142. Griffith, D.L., O'Donnell, M.J., Pottorf, R.S., Scott, W.L., & Porco, J.A.Jr. (1997) Tandem UPS: Sequential mono- and dialkylation of resin-bound glycine via automated synthesis. Tetrahedron Lett., 38, 8821-8824. #9697

143. Grotli, M., Eritja, R., & Sproat, B. (1997) Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras. Tetrahedron, 53, 11317-11346. #9406

144. Guo, Z.W., Nakahara, Y., & Ogawa, T. (1997) Solid-phase synthesis of the CD52 glycopeptide carrying an N-linked core pentasaccharide structure. Angew. Chem. Int. Ed., 36, 1464-1466. #12512

145. Guo, Z.W., Nakahara, Y., & Ogawa, T. (1997) Solid-phase synthesis of CD52 glycopeptide and an efficient route to Asn-core pentasaccharide conjugate. Bioorg. Med. Chem., 5, 1917-1924. #10199

146. Guo, Z.W., Nakahara, Y., & Ogawa, T. (1997) Solid-phase synthesis of a glycosylated peptide fragment of the il-8 receptor containing two vicinal oligosaccharide chains. Carbohyd. Res., 303, 373-377. #10200

147. Guzaev, A., & Lonnberg, H. (1997) A novel solid support for synthesis of 3'-phosphorylated chimeric oligonucleotides containing internucleosidic methyl phosphotriester and methylphosphonate linkages. Tetrahedron Lett., 38, 3989-3992. #9056

148. Hakala, H., Heinonen, P., Iitia, A., & Lonnberg, H. (1997) Detection of oligonucleotide hybridization on a single microparticle by time-resolved fluorometry: Hybridization assays on polymer particles obtained by direct solid phase assembly of the oligonucleotide probes. Bioconjug. Chem., 8, 378-384. #9371

149. Hall, D.G., & Schultz, P.G. (1997) Synthesis of diverse ethoxyformacetal oligomers. Toward libraries of metal-coordinating unnatural biopolymers. Tetrahedron Lett., 38, 7825-7828. #9681

150. Hall, S.E. (1997) Recent advances in solid-phase synthesis. In W.H. Moos, M.R. Pavia, B.K. Kay & A.D. Ellington (Eds.), Annual Reports in Combinatorial Chemistry and Molecular Diversity. (pp. 30-40). ESCOM, Leiden. #8614

151. Halm, C., Evarts, J., & Kurth, M.J. (1997) A new attachment/cleavage strategy: Polymer-bound allylic sulfones in a solid-phase route to trisubstituted olefins. Tetrahedron Lett., 38, 7709-7712. #9677

152. Han, H., & Janda, K.D. (1997) Multipolymer-supported substrate and ligand approach to the sharpless asymmetric dihydroxylation. Angew. Chem. Int. Ed., 36, 1731-1733. #12513

153. Harper, S.J., Brown, T., Feehally, J., Pringle, J.H., Stewart, A.S., McKeen, C.M., & Bailey, E. (1997) A comparative study of digoxigenin, 2,4-dinitrophenyl, and alkaline phosphatase as deoxyoligonucleotide labels in non-radioisotopic in situ hybridisation. J. Clin. Pathol., 50, 686-690. #9942

154. Harriman, G.C.B. (1997) Synthesis of small and medium sized 2,2-disubstituted lactams via the "intramolecular" three component Ugi reaction. Tetrahedron Lett., 38, 5591-5594. #9306

155. Harrison, J.G., & Balasubramanian, S. (1997) A convenient synthetic route to oligonucleotide conjugates. Bioorg. Med. Chem. Lett., 7, 1041-1046. #10027

156. Hasan, A., Stengele, K.P., Giegrich, H., Cornwell, P., Isham, K.R., Sachleben, R.A., Pfleiderer, W., & Foote, R.S. (1997) Photolabile protecting groups for nucleosides: Synthesis and photodeprotection rates. Tetrahedron, 53, 4247-4264. #9171

157. Haslanger, M. F. Technology and drug discovery: Accomplishment and projections. In: W. Hori. (Eds.) 1996; International Business Communications,Inc., Southborough p.7.3.1 #8889

158. Hayashi, Y., Harada, T., Katada, J., & Uno, I. (1997) Combinatorial chemical approaches as an efficient tool for discovering GPIIb/IIIa anatagonists. Drugs Future, 22, 1367-1373. #12121

159. Hegedus, L.S. (1997) Transition metals in organic synthesis: Highlights for the year 1995 [Review]. Coord. Chem. Rev., 161, 129-255. #9536

160. Heinonen, P., & Lonnberg, H. (1997) A novel solid support for derivatization and subsequent N-alkylation of secondary amines: Preparation of N-alkylated 5- and 6-alkoxy-1,2,3,4-tetrahydroisoquinolines via Mitsunobu reaction. Tetrahedron Lett., 38, 8569-8572. #9692

161. Heizmann, G., & Eberle, A.N. (1997) Xanthines as a scaffold for molecular diversity. Mol. Diversity, 2, 171-174. #8531

162. Hendrix, C., Rosemeyer, H., Verheggen, I., Seela, F., Vanaerschot, A., & Herdewijn, P. (1997) 1',5'-Anhydrohexitol oligonucleotides: Synthesis, base pairing and recognition by regular oligodeoxyribonucleotides and oligoribonucleotides. Chem. Eur. J., 3, 110-120. #9133

163. Hermkens, P.H.H., Ottenheijm, H.C.J., & Rees, D.C. (1997) Solid-phase organic reactions II: A review of the literature Nov 95-Nov 96. Tetrahedron, 53, 5643-5678. #8599

164. Hernandez, A.S., & Hodges, J.C. (1997) Solid-supported tert-alkoxycarbonylation reagents for anchoring of amines during solid phase organic synthesis. J. Org. Chem., 62, 3153-3157. #9102

165. Hilberink, P., van Aelst, S., Vink, T. Q., van Gool, E., and Kaspersen, F. Automated organic chemical synthesis. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.93 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8287

166. Hird, N.W., Irie, K., & Nagai, K. (1997) Solid phase synthesis of 2-aminobutadienes using a piperazine linker. Tetrahedron Lett., 38, 7111-7114. #9577

167. Ho, C.Y., & Kukla, M.J. (1997) Carbamate linkers as latent N-methylamines in solid phase synthesis. Tetrahedron Lett., 38, 2799-2802. #8784

168. Hodge, P. (1997) Polymer-supported organic reactions: What takes place in the beads? Chem. Soc. Rev., 26, 417-424. #10534

169. Hoekstra, W.J., Greco, M.N., Yabut, S.C., Hulshizer, B.L., & Maryanoff, B.E. (1997) Solid-phase synthesis via N-terminal attachment to the 2-chlorotrityl resin. Tetrahedron Lett., 38, 2629-2632. #8783

170. Hoeprich, P. D. Jr. New approaches to automated solid phase organic synthesis. In: W. Hori. (Eds.) 1996; International Business Communications,Inc., Southborough p.6.2.1 #8888

171. Hoffmann, R., Hoffmann, T., Tholey, A., Schulte, A.C., & Kalbitzer, H.R. (1997) Synthesis and NMR spectroscopy of peptides containing either phosphorylated or phosphonylated cis- or trans-4-hydroxy-l-proline. J. Pept. Res., 49, 163-173. #9227

172. Holmes, C.P. (1997) Model studies for new o-nitrobenzyl photolabile linkers: Substituent effects on the rates of photochemical cleavage. J. Org. Chem., 62, 2370-2380. #8655

173. Holmes, D.L., Smith, E.M., & Nowick, J.S. (1997) Solid-phase synthesis of artificial beta-sheets. J. Amer. Chem. Soc., 119, 7665-7669. #10216

174. Honda, M., Morita, H., & Nagakura, I. (1997) Deprotection of allyl groups with sulfinic acids and palladium catalyst. J. Org. Chem., 62, 8932-8936. #10217

175. Hsieh, H.P., Chen, S.T., & Wang, K.T. (1997) Microwave induced synthesis of 3,4-dihydro-2h-pyran-2-carboxaldehyde: A versatile linker for solid phase combinatorial library. J. Chin. Chem. Soc., 44, 597-600. #10222

176. Hsieh, Y.F., Gordon, N., Regnier, F., Afeyan, N., Martin, S.A., & Vella, G.J. (1997) Multidimensional chromatography coupled with mass spectrometry for target-based screening. Mol. Diversity, 2, 189-196. #8866

177. Ito, Y., & Ogawa, T. (1997) Intramolecular aglycon delivery on polymer support: Gatekeeper monitored glycosilation. J. Amer. Chem. Soc., 119, 5562-5566. #13782

178. Iyer, R.P., Yu, D., Xie, J., Zhou, W., & Agrawal, S. (1997) The use of gaseous ammonia for the deprotection and cleavage steps during the solid-phase synthesis of oligonucleotides, and analogs. Bioorg. Med. Chem. Lett., 7, 1443-1448. #9184

179. Jakobsson, E., Hinz, M., & Seliger, H. (1997) Synthesis and evaluation of oligonucletides of high purity. Nucleosides Nucleotides, 16, 883-887. #9326

180. James, I.W. (1997) Recent publications in solid-phase chemistry: Part 1. Mol. Diversity, 2, 175-180. #8532

181. James, I.W. (1997) A compendium of solid-phase chemistry publications. In W.H. Moos, M.R. Pavia, B.K. Kay & A.D. Ellington (Eds.), Annual Reports in Combinatorial Chemistry and Molecular Diversity. (pp. 326-344). ESCOM, Leiden. #8633

182. James, K.D., Von Kiedrowski, G., & Ellington, A.D. (1997) Incorporation of 5'-N-Boc-2',5'-dideoxynucleoside-3'-O-phosphoramidites into oligonucleotides by automated synthesis. Nucleosides Nucleotides, 16, 1821-1836. #12254

183. Johnson, W.T., Zhang, P.M., & Bergstrom, D.E. (1997) The synthesis and stability of oligodeoxyribonucleotides containing the deoxyadenosine mimic 1-(2'-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide. Nucl. Acid. Res., 25, 559-567. #8404

184. Jones, L.Jr., Schumm, J.S., & Tour, J.M. (1997) Rapid solution and solid phase syntheses of oligo(1,4-phenylene ethynylene)s with thioester termini: Molecular scale wires with alligator clips. Derivation of iterative reaction efficiencies on a polymer support. J. Org. Chem., 62, 1388-1410. #12515

185. Jordan, S., Schwemler, C., Kosch, W., Kretschmer, A., Schwenner, E., Stropp, U., & Mielke, B. (1997) Synthesis of new building blocks for peptide nucleic acids containing monomers with variations in the backbone. Bioorg. Med. Chem. Lett., 7, 681-686. #10024

186. Jordan, S., Schwemler, C., Kosch, W., Kretschmer, A., Stropp, U., Schwenner, E., & Mielke, B. (1997) New hetero-oligomeric peptide nucleic acids with improved binding properties to complementary DNA. Bioorg. Med. Chem. Lett., 7, 687-690. #10025

187. Junggebauer, J., & Neumann, W.P. (1997) An improved synthesis of a polymer-supported distannane and its application to radical formation. Tetrahedron, 53, 1301-1310. #8536

188. Kahne, D. (1997) Combinatorial approaches to carbohydrates. Curr. Opin. Chem. Biol., 1, 130-135. #8772

189. Kajimoto, T., & Ida, Y. (1997) Glycotechnology: Synthesis of carbohydrates and carbohydrate mimetics [japanese]. J. Syn. Org. Chem. Jpn., 55, 393-401. #9107

190. Kamaike, K., Takahashi, H., Kakinuma, T., Morohoshi, K., & Ishido, Y. (1997) Oligonucleotide synthesis by the use of a 2-(levulinyloxymethyl)-5-nitrobenzoyl group as the novel base-labile protecting group for the 5'-hydroxyl groups of ribonucleoside and 2'-deoxyribonucleoside 3'-phosphoramidites. Tetrahedron Lett., 38, 6857-6860. #9548

191. Kantorowski, E.J., & Kurth, M.J. (1997) Dipolar cycloadditions in solid-phase organic synthesis (SPOS). Mol. Diversity, 2, 207-216. #8868

192. Kantorowski, E.J., & Kurth, M.J. (1997) Solid-phase synthesis of isoxazoles and isoxazolines: En route to a new class of ionophores. J. Org. Chem., 62, 6797-6803. #9658

193. Kappes, T., & Waldmann, H. (1997) Enzymatic synthesis of peptide conjugates: Tools for the study of biological signal transduction [review]. Liebig. Ann., 803-813. #9109

194. Katritzky, A.R., Toader, D., Watson, K., & Kiely, J.S. (1997) New synthesis of SASRIN(TM) resin. Tetrahedron Lett., 38, 7849-7850. #9687

195. Katritzky, A.R., Xie, L., & Zhang, G. (1997) Synthesis of primary amines via nucleophilic addition of organometallic reagents to aldimines on solid support. Tetrahedron Lett., 38, 7011-7014. #9576

196. Kay, C., Murray, P.J., Sandow, L., & Holmes, A.B. (1997) A novel, chemically robust, amine releasing linker. Tetrahedron Lett., 39, 6941-6944. #9549

197. Kealy, M. (1997) Automation of 96-well solid phase extraction procedures with the Packard MultiPROBE. Lab. Automat. New., 2, 6-9. #9969

198. Keifer, P.A. (1997) High-resolution NMR techniques for solid-phase synthesis and combinatorial chemistry. Drug Disc. Today, 2, 468-478. #9585

199. Kellam, B., Bycroft, B.W., & Chhabra, S.R. (1997) Solid phase applications of Dde and the analogue Nde: Synthesis of trypanothione disulphide. Tetrahedron Lett., 38, 4849-4852. #9042

200. Kempin, U., Hennig, L., Knoll, D., Welzel, P., Muller, D., Markus, A., & Van Heijenoort, J. (1997) Moenomycin A: New chemistry that allows to attach the antibiotic to reporter groups, solid supports, and proteins. Tetrahedron, 53, 17669-17690. #12205

201. Kennedy, R. M. ACID for the Tecan(TM): An automated combinatorial interface demonstration. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.155 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8297

202. Khound, S., & Das, P.J. (1997) Solid phase synthesis of N-arylazoindoles. Tetrahedron, 53, 9749-9754. #9479

203. Kibbey, C. E., Robertson, G. A., MacDonald, A., and DeWitt, S. H. An automated system for the purification of combinatorial libraries by semi-preparative HPLC. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.336 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8321

204. Kick, E.K., Roe, D.C., Skillman, A.G., Liu, G.C., Ewing, T.J.A., Sun, Y.X., Kuntz, I.D., & Ellman, J.A. (1997) Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin d. Chem. Biol., 4, 297-307. #9205

205. Kiely, J.S., Hayes, T.K., Griffith, M.C. & Pei, Y. (1997) Synthesis tools for solid-phase synthesis. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 99-122). American Chemical Society, Washington,DC. #11697

206. Kihlberg, J., Elofsson, M., & Salvador, L.A. (1997) Direct synthesis of glycosylated amino acids from carbohydrate peracetates and Fmoc amino acids: Solid-phase synthesis of biomedicinally interesting glycopeptides. Methods Enzymol., 289, 221-245. #9934

207. Kihlberg, J., & Elofsson, M. (1997) Solid-phase synthesis of glycopeptides: Immunological studies with T cell stimulating glycopeptides. Curr. Med. Chem., 4, 85-116. #12516

208. Kim, J.M., & Roy, R. (1997) Oligomeric glycopeptidomimetics bearing the cancer related T(N)-antigen. Tetrahedron Lett., 38, 3487-3490. #8848

209. Kim, J.M., & Ahn, K.D. (1997) Organic synthesis of polymer support. Kobunja Kwahak Kwa Kisul, 8, 441-447. #9639

210. Kim, M.S., & Guengerich, F.P. (1997) Synthesis of oligonucleotides containing the ethylene dibromide-derived DNA adducts s-[2-(n-7-guanyl)ethyl]glutathione, s-[2-(n-2-guanyl)ethyl]glutathione, and s-[2-(o-6-guanyl)ethyl]glutathione at a single site. Chem. Res. Toxicol., 10, 1133-1143. #10244

211. Kim, S.W., Ahn, S.Y., Koh, J.S., Lee, J.H., Ro, S., & Cho, H.Y. (1997) Solid phase synthesis of hydantoin library using a novel cyclization and traceless cleavage step. Tetrahedron Lett., 38, 4603-4606. #8874

212. Kiselyov, A.S., & Armstrong, R.W. (1997) Solid support synthesis of tetrahydroquinolines via the Grieco three component condensation. Tetrahedron Lett., 38, 6163-6166. #9315

213. Klich, G., Paulsen, H., Meyer, B., Meldal, M., & Bock, K. (1997) Synthesis and characterisation of highly glycosylated glycopeptides with T-n-antigenic structures corresponding to human glycophorin A(N). Carbohyd. Res., 299, 33-48. #9146

214. Knoll, R., Furste, J.P., & Bald, R. (1997) Complete identification of nonbridging phosphate oxygens involved in hammerhead cleavage. RNA Publ. RNA Soc., 3, 132-140. #9958

215. Knudsen, H., & Nielsen, P.E. (1997) Application of peptide nucleic acid in cancer therapy [review]. Anti-Cancer Drug., 8, 113-118. #8365

216. Kobayashi, S., & Moriwaki, M. (1997) 5-(4'-Chloromethylphenyl)pentylpolystyrene resin (CMPP resin). A new linker resin for solid-phase organic synthesis under Lewis acidic conditions. Tetrahedron Lett., 38, 4251-4254. #8700

217. Kobertz, W.R., & Essigmann, J.M. (1997) Solid-phase synthesis of oligonucleotides containing a site-specific psoralen derivative. J. Amer. Chem. Soc., 119, 5960-5961. #9508

218. Kofoed, T., Rasmussen, P.B., Valentinhansen, P., & Pedersen, E.B. (1997) Oligodeoxynucleotides with extended 3'- and 5'-homologous internucleotide linkages. Acta Chem. Scand., 51, 318-324. #9172

219. Konopelski, J.P., Filonova, L.K., & Olmstead, M.M. (1997) Dipeptide surrogates containing asparagine-derived tetrahydropyrimidinones: Preparation, structure, and use in solid phase synthesis. J. Amer. Chem. Soc., 119, 4305-4306. #9125

220. Krchnak, V., & Weichsel, A.S. (1997) Polymer-supported synthesis of diverse perhydro-1,4-diazepine-2,5-diones. Tetrahedron Lett., 38, 7299-7302. #6947 4337

221. Krchnak, V., Weichsel, A.S., Lebl, M., & Felder, S. (1997) Automated solid-phase organic synthesis in micro-plate wells. Synthesis of N-(alkoxy-acyl)amino alcohols. Bioorg. Med. Chem. Lett., 7, 1013-1016. #6948 4222

222. Kris, R. Strategies for integration of combinatorial chemistry synthesis and screening. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.123 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8291

223. Kroll, F.E., Morphy, R., Rees, D., & Gani, D. (1997) Resin-immobilized benzyl and aryl vinyl sulfones: New versatile traceless linkers for solid-phase organic synthesis. Tetrahedron Lett., 38, 8573-8576. #9581

224. Kruijtzer, J.A.W., Lefeber, D.J., & Liskamp, R.M.J. (1997) Approaches to the synthesis of ureapeptoid peptidomimetics. Tetrahedron Lett., 38, 5335-5338. #9053

225. Kuimelis, R.G., & Mclaughlin, L.W. (1997) Application of a 5'-bridging phosphorothioate to probe divalent metal and hammerhead ribozyme mediated RNA cleavage. Bioorg. Med. Chem., 5, 1051-1061. #9494

226. Kumar, H.M.S., Mohanty, P.K., Kumar, M.S., & Yadav, J.S. (1997) Microwave promoted rapid dehydration of aldoximes to nitriles on a solid support. Syn. Commun., 27, 1327-1333. #12517

227. Kumar, P., & Misra, K. (1997) A new strategy for the synthesis of phosphorothioates of 2'-deoxyriboligonucleotides. Ind. J. Chem. B-Org. Chem. Med. Chem., 36, 1000-1004. #11031

228. Kumar, P., Gupta, K.C., Rosch, R., & Seliger, H. (1997) Solid phase synthesis of oligonucleotides bearing phosphate and thiophosphate at their 3'-termini. Chem. Lett., 1231-1232. #10256

229. Kumar, S., Cheng, X., Roberts, R.J., Walker, R.T., Jones, G.D., & Horton, J.R. (1997) DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase. Nucl. Acid. Res., 25, 2773-2783. #9941

230. Kumpinsh, V.K., Litsis, N.G., Renkhof, R.F., Stankevich, E.I., Berzin, V.M., & et al. (1997) Synthetic 15 - 19-meric oligoribonucleotides as models for translation initiation of the phage fr replicase gene. Bioorganicheskaia Khimiia, 21, 920-924. #9330

231. Kurth, M.J. (1997) Polymer supported synthesis of organic compounds and libraries. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 39-64). John Wiley & Sons,Inc., New York. #8352

232. Lam, K.S., Lebl, M., & Krchnak, V. (1997) The "one-bead one-compound" combinatorial library method. Chem. Rev., 97, 411-448. #6980 4444

233. Lazar, L., Lakatos, A.G., Fulop, F., Bernath, G., & Riddell, F.G. (1997) Five-component equilibria of ring-chain tautomeric mixtures derived from 3-amino-1,2-propanediol and aromatic aldehydes. Tetrahedron, 53, 1081-1088. #8266

234. Le Hetet, C., David, M., Carreaux, F., Carboni, B., & Sauleau, A. (1997) Synthesis of functionalized gamma- and delta-lactones via polymer-bound epoxides. Tetrahedron Lett., 38, 5153-5156. #9034

235. Leach, M. (1997) Discovery on a credit card? Drug Disc. Today, 2, 253. #12268

236. Lee, J., Murray, W.V., & Rivero, R.A. (1997) Solid phase synthesis of 3,4-disubstituted-7-carbamoyl-1,2,3,4-tetrahydroquinoxalin-2-ones. J. Org. Chem., 62, 3874-3879. #9075

237. Lehmann, T.E., Greenberg, W.A., Liberles, D.A., Wada, C.K., & Dervan, P.B. (1997) Triple-helix formation by pyrimidine oligonucleotides containing nonnatural nucleosides with extended aromatic nucleobases: Intercalation from the major groove as a method for recognizing c-center-dot-g and t-center-dot-a base pairs. Helv. Chim. Acta, 80, 2002-2022. #10263

238. Lehotay, S.J., & Valverde-Garcia, A. (1997) Evaluation of different solid-phase traps for automated collection and clean-up in the analysis of multiple pesticides in fruits and vegetables after supercritical fluid extraction. J. Chromatogr. A, 765, 69-84. #8523

239. Lemmo, A.V., Fisher, J.T., Geysen, H.M., & Rose, D.J. (1997) Characterization of an inkjet chemical microdispenser for combinatorial library synthesis. Anal. Chem., 69, 543-551. #8268

240. Lesiak, K.B., Torrence, P.F., & Uznanski, B. (1997) The solid-phase synthesis of 2'-5'-linked oligoriboadenylates containing 8-bromoadenine. Appl. Biochem. Biotech., 67, 33-44. #9938

241. Li, H., Fedorova, O.S., Trumble, W.R., Fletcher, T.R., & Czuchajowski, L. (1997) Site-specific photomodification of DNA by porphyrin-oligonucleotide conjugates synthesized via a solid phase H-phosphonate approach. Bioconjug. Chem., 8, 49-56. #9372

242. Li, W., & Yan, B. (1997) A direct comparison of the mixing efficiency in solid-phase organic synthesis by single bead IR and fluorescence spectroscopy. Tetrahedron Lett., 38, 6485-6488. #9322

243. Li, W., Liu, G., & Yun, L. (1997) Small molecular chemical libraries generated through solid phase organic synthesis. Huaxue Jinzhan, 9, 239-252. #9635

244. Liang, R., Loebach, J., Horan, N., Ge, M., Thompson, C., Yan, L., & Kahne, D. (1997) Polyvalent binding to carbohydrates immobilized on an insoluble resin. Proc. Natl. Acad. Sci. USA, 94, 10554-10559. #9640

245. Liang, R. (1997) Part I. Synthesis and conformational studies of o-glycopeptides. Part II. Parallel synthesis and screening of a solid phase carbohydrate library. Princeton University, Princeton,NJ,USA; 1292 p. #9657

246. Liebe, B., & Kunz, H. (1997) Solid-phase synthesis of a tumor-associated sialyl-TN antigen glycopeptide with a partial sequence of the "tandem repeat" of the MUC-1 mucin. Angew. Chem. Int. Ed., 36, 618-621. #12518

247. Liebe, B., & Kunz, H. (1997) Solid-phase synthesis of a sialyl-Tn-glycoundecapeptide of the MUC1 repeating unit. Helv. Chim. Acta, 80, 1473-1482. #9399

248. Lister, M. D. and Janzen, W. Management of a centralized high throughput screening facility. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.43 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8283

249. Llinares, M., & Roy, R. (1997) Multivalent neoglycoconjugates: Solid-phase synthesis of N-linked alpha-sialodendrimers. Chem. Commun., 2119-2120. #10270

250. Lokey, R.S., Kwok, Y., Guelev, V., Pursell, C.J., Hurley, L.H., & Iverson, B.L. (1997) A new class of polyintercalating molecules. J. Amer. Chem. Soc., 119, 7202-7210. #9419

251. Louter, A.J.H., Bosma, E., Schipperen, J.C.A., Vreuls, J.J., & Brinkman, U.A. (1997) Automated online solid-phase extraction-gas chromatography with nitrogen-phosphorus detection: Determination of benzodiazepines in human plasma. J. Chromatogr. B Biomed. Sci. Appl., 689, 35-43. #8469

252. Lowe, G., & Vilaivan, T. (1997) Solid-phase synthesis of novel peptide nucleic acids. J. Chem. Soc. Perkin Trans. 1, 555-560. #12519

253. Lutz, E.S.M., Irth, H., Tjaden, U.R., & Vandergreef, J. (1997) Biochemical detection for direct bead surface analysis. Anal. Chem., 69, 4878-4884. #10272

254. Lyttle, M.H., Adams, H., Hudson, D., & Cook, R.M. (1997) Versatile linker chemistry for synthesis of 3'-modified DNA. Bioconjug. Chem., 8, 193-198. #9369

255. Ma, M.Y.X., Dignam, J.C., Fong, G.W., Li, L., Gray, S.H., Jacob-Samuel, B., & George, S.T. (1997) Evaluation of 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) as a new sulfurising reagent in combination with labile exocyclic amino protecting groups for solid-phase oligonucleotide synthesis. Nucl. Acid. Res., 25, 3590-3593. #9345

256. Maclean, D., Schullek, J.R., Murphy, M.M., Ni, Z.J., Gordon, E.M., & Gallop, M.A. (1997) Encoded combinatorial chemistry: Synthesis and screening of a library of highly functionalized pyrrolidines. Proc. Natl. Acad. Sci. USA, 94, 2805-2810. #8572

257. Maehr, H. (1997) Combinatorial chemistry in drug research from a new vantage point. Bioorg. Med. Chem., 5, 473-491. #9221

258. Mag, M., Muth, J., Jahn, K., Peyman, A., Kretzschmar, G., Engels, J.W., & Uhlmann, E. (1997) Synthesis and binding properties of oligodeoxynucleotides containing phenylphosphon(othio)ate linkages. Bioorg. Med. Chem., 5, 2213-2220. #10275

259. Maier, E., Meier-Ewert, S., Bancroft, D., & Lehrach, H. (1997) Automated array technologies for gene expression profiling. Drug Disc. Today, 2, 315-324. #9852

260. Major, J. Challenges and opportunities in high throughput screening: Implications for new technologies. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.25 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8281

261. Makara, G.M., & Marshall, G.R. (1997) A facile synthesis of 3-substituted pipecolic acids, chimeric amino acids. Tetrahedron Lett., 38, 5069-5072. #9031

262. Markiewicz, W.T., Groger, G., Rosch, R., Zebrowska, A., Markiewicz, M., Klotz, M., Hinz, M., Godzina, P., & Seliger, H. (1997) A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing. Nucl. Acid. Res., 25, 3672-3680. #10277

263. Marsh, I.R., & Bradley, M. (1997) Solid phase synthesis of polyamine conjugates for the study of trypanothione reductase. Tetrahedron, 53, 17317-17334. #10278

264. Marsh, I.R., Smith, H.K., Leblanc, C., & Bradley, M. (1997) Synthetic methods for polyamine linkers and their application to combinatorial chemistry. Mol. Diversity, 2, 165-170. #8530

265. Marti, R.E., Bleicher, K.H., & Bair, K.W. (1997) Solid phase synthesis of beta-peptides via Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones. Tetrahedron Lett., 38, 6145-6148. #9313

266. Marti, R.E., Yan, B., & Jarosinski, M.A. (1997) Solid-phase synthesis via 5-oxazolidinones: Ring-opening reactions with amines and reaction monitoring by single-bead FT-IR microspectroscopy. J. Org. Chem., 62, 5615-5618. #9415

267. Marx, M.A., Grillot, A.L., Louer, C.T., Beaver, K.A., & Bartlett, P.A. (1997) Synthetic design for combinatorial chemistry: Solution and polymer-supported synthesis of polycyclic lactams by intramolecular cyclization of azomethine ylides. J. Amer. Chem. Soc., 119, 6153-6167. #9486

268. Marzinzik, A.L., & Felder, E.R. (1997) Combinatorial libraries on rigid scaffolds: Solid phase synthesis of variably substituted pyrazoles and isoxazoles. Molecules, 2, 17-30. #8570

269. Mata, E.G. (1997) Beta-lactams on solid support: Mild and efficient removal of penicillin derivatives from Merrifield resin using aluminum chloride. Tetrahedron Lett., 38, 6335-6338. #9319

270. Matray, T.J., Yoo, D.J., McMinn, D.L., & Greenberg, M.M. (1997) Synthesis of oligonucleotides containing 3'-alkylcarboxylic acids using a palladium labile oligonucleotide solid phase synthesis support. Bioconjug. Chem., 8, 99-102. #9274

271. Matthews, J., & Rivero, R.A. (1997) Base-promoted solid-phase synthesis of substituted hydantoins and thiohydantoins. J. Org. Chem., 62, 6090-6092. #10284

272. Matulicadamic, J., Haeberli, P., Direnzo, A.B., Mokler, V.R., Maloney, L., Beigelman, L., Usman, N., & Wincott, F.E. (1997) Synthesis and incorporation of 5'-amino- and 5'-mercapto-5'-deoxy-2'-o-methyl nucleosides into hammerhead ribozymes. Nucleosides Nucleotides, 16, 1933-1950. #10285

273. Maurer, K.W., & Kenyon, G.L. (1997) Solid support-bound synthesis of polyfunctional unsymmetrical ureas. Bioorg. Chem., 25, 277-281. #12209

274. Mayer, J.P., Lewis, G.S., Curtis, M.J., & Zhang, J. (1997) Solid phase synthesis of quinazolinones. Tetrahedron Lett., 38, 8445-8448. #9670

275. McMinn, D.L., & Greenberg, M.M. (1997) Synthesis of oligonucleotides containing 3'-alkyl amines using N-isobutyryl protected deoxyadenosine phosphoramidite. Tetrahedron Lett., 38, 3123-3126. #8793

276. Meinjohanns, E., Meldal, M., Jensen, T., Werdelin, O., Galli-Stampino, L., Mouritsen, S., & Bock, K. (1997) Versatile solid-phase thiolytic reduction of azido and N-Dts groups in the synthesis of haemoglobin (67-76) O-glycopeptides and photoaffinity labelled analogues to study glycan T-cell specificity. J. Chem. Soc. Perkin Trans. 1, 871-884. #12520

277. Meisenbach, M., Echner, H., & Voelter, W. (1997) New methoxy-substituted 9-phenylxanthen-9-ylamine linkers for the solid phase synthesis of protected peptide amides. Chem. Commun., 849-850. #9124

278. Meisenbach, M., & Voelter, W. (1997) New methoxy-substituted tritylamine linkers for the solid phase synthesis of protected peptide amides. Chem. Lett., 1265-1266. #10289

279. Meissner, A., Bloch, P., Humpfer, E., Spraul, M., & Sorensen, O.W. (1997) Reduction of inhomogeneous line broadening in two-dimensional high-resolution mas nmr spectra of molecules attached to swelled resins in solid-phase synthesis. J. Amer. Chem. Soc., 119, 1787-1788. #8396

280. Meldal, M., & St.Hilaire, P.M. (1997) Synthetic methods of glycopeptide assembly, and biological analysis of glycopeptide products. Curr. Opin. Chem. Biol., 1, 552-563. #10529

281. Meldal, M. (1997) Properties of solid supports. Methods Enzymol., 289, 83-104. #9929

282. Meldgaard, M., Nielsen, N.K., Bremner, M., Pedersen, O.S., Olsen, C.E., & Wengel, J. (1997) Automated preparation of branched oligodeoxyribonucleotide analogs using arabino-uridine as branching nucleotide. J. Chem. Soc. Perkin Trans. 1, 1951-1955. #9379

283. Mellor, S.L., & Chan, W.C. (1997) 4-[2,4-Dimethoxyphenyl(N-fluoren-9-ylmethoxycarbonyl-N-alkylaminooxy)methyl]phenoxymethyl polystyrene: A multiple solid-phase approach to N-alkylhydroxamic acids. Chem. Commun., 2005-2006. #10493

284. Mellor, S.L., McGuire, C., & Chan, W.C. (1997) N-Fmoc-Aminooxy-2-chlorotrityl polystyrene resin: A facile solid-phase methodology for the synthesis of hydroxamic acids. Tetrahedron Lett., 38, 3311-3314. #8803

285. Mellor, S.L., & Chan, W.C. (1997) A multiple solid-phase approach to N-alkylhydroxamic acids. Chem. Commun., 2005-2006. #11398

286. Merchan, F.L., Merino, P., & Tejero, T. (1997) A new entry to glycosylamines. Glycoconjugate J., 14, 497-499. #9480

287. Mitra, S., & Sreekumar, K. (1997) Polymeric benzyltriethylammonium dichloroiodate and dibromoiodate: Preparation and use as synthetic reagents. Ind. J. Chem. B-Org. Chem. Med. Chem., 36B, 133-136. #8645

288. Mjalli, A.M.M. (1997) Application of automated parallel synthesis. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 327-354). American Chemical Society, Washington,DC. #11704

289. Moos, W.H. (1997) Introduction: Combinatorial chemistry approaches the next millenium. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 1-16). American Chemical Society, Washington,DC. #11694

290. Moos, W. H. Drug discovery meets biotech: How automation enables the 'better-faster-cheaper' paradigm. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.1 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8279

291. Morningstar, M.L., Kreutzer, D.A., & Essigmann, J.M. (1997) Synthesis of oligonucleotides containing two putatively mutagenic DNA lesions: 5-Hydroxy-2'-deoxyuridine and 5-hydroxy-2'-deoxycytidine. Chem. Res. Toxicol., 10, 1345-1350. #10294

292. Morovjan, G., Szakacs, G., & Fekete, J. (1997) Monitoring of selected metabolites and biotransformation products from fermentation broths by high-performance liquid chromatography. J. Chromatogr. A, 763, 165-172. #8524

293. Mullah, B., & Andrus, A. (1997) Automated synthesis of double dye-labeled oligonucleotides using tetramethylrhodamine (TAMRA) solid supports. Tetrahedron Lett., 38, 5751-5754. #9308

294. Munch, U., & Pfleiderer, W. (1997) The (2-cyano-1-phenyl)ethoxycarbonyl (cpeoc) group: A new protecting group for oligoribonucleotide synthesis. Nucleosides Nucleotides, 16, 801-808. #9422

295. Murray, C.W., Clark, D.E., Auton, T.R., Firth, M.A., Li, J., Sykes, R.A., Waszkowycz, B., Westhead, D.R., & Young, S.C. (1997) PRO-SELECT: Combining structure-based drug design and combinatorial chemistry for rapid lead discovery. 1. Technology. J. Comput. Aid. Molec. Design, 11, 193-207. #9269

296. Naik, S.D., & Doraiswamy, L.K. (1997) Mathematical modeling of solid-liquid phase-transfer catalysis. Chem. Eng. Sci., 52, 4533-4546. #10567

297. Nair, H.K., & Burton, D.J. (1997) Facile synthesis of fluorinated phosphonates via photochemical and thermal reactions. J. Amer. Chem. Soc., 119, 9137-9143. #10297

298. Nakahara, Y., Ito, Y., & Ogawa, T. (1997) Total synthesis of B-chain of human alpha2HS glycoprotein. Tetrahedron Lett., 38, 7211-7214. #9562

299. Nastri, F., Lombardi, A., Morelli, G., Maglio, O., Dauria, G., Pedone, C., & Pavone, V. (1997) Hemoprotein models based on a covalent helix-heme-helix sandwich. 1.Design, synthesis, and characterization. Chem. Eur. J., 3, 340-349. #9136

300. Natt, F., & Haner, R. (1997) Lipocap: A lipophilic phosphoramidite-based capping reagent. Tetrahedron, 53, 9629-9636. #9478

301. Nefzi, A., Ostresh, J.M., & Houghten, R.A. (1997) Solid phase synthesis of 1,3,4,7-tetrasubstituted perhydro-1,4-diazepine-2,5-diones. Tetrahedron Lett., 38, 4943-4946. #9038

302. Nefzi, A., Ostresh, J.M., & Houghten, R.A. (1997) The current status of heterocyclic combinatorial libraries. Chem. Rev., 97, 449-472. #8567

303. Nefzi, A., Ostresh, J.M., Meyer, J.P., & Houghten, R.A. (1997) Solid phase synthesis of heterocyclic compounds from linear peptides: Cyclic ureas and thioureas. Tetrahedron Lett., 38, 931-934. #8407

304. Negro, A., Onisto, M., Grassato, L., Caenazzo, C., & Garbisa, S. (1997) Recombinant human TIMP-3 from Escherichia coli: Synthesis, refolding, physico-chemical and functional insights. Protein Eng., 10, 593-599. #9368

305. Neil, W., Weller, H. N., Lawrence, R. M., and Young, M. G. Adaptation of liquid handlers to the automation of combinatorial organic chemistry. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.107 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8288

306. Nelson, J.S., Fearon, K.L., Nguyen, M.Q., McCurdy, S.N., Frediani, J.E., Foy, M.F., & Hirschbein, B.L. (1997) N3'-]p5' oligodeoxyribonucleotide phosphoramidates: A new method of synthesis based on a phosphoramidite amine-exchange reaction. J. Org. Chem., 62, 7278-7287. #10299

307. Nelson, P.S., Muthini, S., Vierra, M., Acosta, L., & Smith, T.H. (1997) Rainbow(TM) universal CPG: A versatile solid support for oligonucleotide synthesis. BioTechniques, 22, 752-756. #12521

308. Nelson, P.S., Muthini, S., Kent, M.A., & Smith, T.H. (1997) 3'-terminal modification oligonucleotides using a universal solid support. Nucleosides Nucleotides, 16, 1951-1959. #12210

309. Newlander, K.A., Chenera, B., Veber, D.F., Yim, N.C., & Moore, M.L. (1997) Simple silyl linker for the solid phase organic synthesis of aryl-containing molecules. J. Org. Chem., 62, 6726-6732. #9660

310. Ngu, K., & Patel, D.V. (1997) A new and efficient solid phase synthesis of hydroxamic acids. J. Org. Chem., 62, 7088-7089. #9629

311. Ngu, K., & Patel, D.V. (1997) Preparation of acid-labile resins with halide linkers and their utility in solid phase organic synthesis. Tetrahedron Lett., 38, 973-976. #8660

312. Nicolaou, K.C., Vourloumis, D., Li, T.H., Pastor, J., Winssinger, N., He, Y., Ninkovic, S., Sarabia, F., Vallberg, H., Roschangar, F., King, N.P., Finlay, M.R., Giannakakou, P., Verdier-Pinard, P., & Hamel, E. (1997) Designed epothilones: Combinatorial synthesis, tubulin assembly properties, and cytotoxic action against taxol-resistant tumor cells. Angew. Chem. Int. Ed., 36, 2097-2103. #9620

313. Nicolaou, K.C., Winssinger, N., Pastor, J., Ninkovic, S., Sarabia, F., He, Y., Vourloumis, D., Yang, Z., Li, T., Giannakakou, P., & Hamel, E. (1997) Synthesis of epothilones A and B in solid and solution phase. [Erratum to document cited in CA127:4950]. Nature, 390, 100-100. #9618

314. Nicolaou, K.C., Winssinger, N., Pastor, J., & DeRoose, F. (1997) A general and highly efficient solid phase synthesis of oligosaccharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE). J. Amer. Chem. Soc., 119, 449-450. #8251

315. Nicolaou, K.C., Winssinger, N., Pastor, J., Ninkovic, S., Sarabia, F., He, Y., Vourloumis, D., Yang, Z., Li, T., Glannakakou, P., & Hamel, E. (1997) Synthesis of epothilones A and B in solid and solution phase. Nature, 387, 268-272. #8642

316. Nicolas, E., Clemente, J., Ferrer, T., Albericio, F., & Giralt, E. (1997) The use of the Nbb-resin for the solid-phase synthesis of peptide alkylesters and alkylamides: Synthesis of leuprolide. Tetrahedron, 53, 3179-3194. #8369

317. Nielsen, J., & Jensen, F.R. (1997) Solid-phase synthesis of small molecule libraries using double combinatorial chemistry. Tetrahedron Lett., 38, 2011-2014. #8457

318. Nilsson, K.G.I., Ljunger, G., & Melin, P.M. (1997) Glycosidase-catalysed synthesis of glycosylated amino acids: Synthesis of Galnac-alpha-Ser and Glcnac-beta-Ser derivatives. Biotechnol. Lett., 19, 889-892. #10304

319. Nugiel, D.A., Wacker, D.A., & Nemeth, G.A. (1997) Facile preparation of chloromethylaryl solid supports using methanesulfonyl chloride and Hunig's base. Tetrahedron Lett., 38, 5789-5790. #9309

320. Nugiel, D.A., & Cornelius, L.A.M. (1997) Facile preparation of 2,6-disubstituted purines using solid-phase chemistry. J. Org. Chem., 62, 201-203. #8750

321. Nuss, J.M., Desai, M.C., Zuckermann, R.N., Singh, R., Renhowe, P.A., Goff, D.A., Chinn, J.P., Wang, L., Dorr, H., Brown, E.G., & Subramanian, S. (1997) Developing a general strategy for the solid supported synthesis of heterocycles: Applications to the generation of molecular diversity and drug discovery. Pure Appl. Chem., 69, 447-452. #9166

322. O'Donnell, M.J., Lugar, C.W., Pottorf, R.S., Zhou, C., Scott, W.L., & Cwi, C.L. (1997) Solid-phase synthesis of unnatural amino acids using unactived alkyl halides. Tetrahedron Lett., 38, 7163-7166. #9560

323. Obrecht, D., Abrecht, C., Grieder, A., & Villalgordo, J.M. (1997) A novel and efficient approach for the combinatorial synthesis of structurally diverse pyrimidines on solid support. Helv. Chim. Acta, 80, 65-72. #8657

324. Ordoukhanian, P., & Taylor, J.S. (1997) Solid-phase supported thymine dimers for the construction of dimer-containing DNA by combined chemical and enzymatic synthesis: A potentially general method for the efficient incorporation of modified nucleotides into DNA. Nucl. Acid. Res., 25, 3783-3786. #9939

325. Ostergaard, S., & Holm, A. (1997) Peptomers: A versatile approach for the preparation of diverse combinatorial peptidomimetic bead libraries. Mol. Diversity, 3, 17-27. #8209

326. Ostergaard, S., & Holm, A. (1997) Synthesis and screening of an indexed motif-library containing non-proteinogenic amino acids. J. Peptide Sci., 3, 123-132. #8581

327. Panek, J.S., & Zhu, B. (1997) Asymmetric crotylation reactions on solid support: Synthesis of stereochemically well-defined polypropionate-like subunits. J. Amer. Chem. Soc., 119, 12022-12023. #10443

328. Park, B.D., Lee, H.I., Ryoo, S.J., & Lee, Y.S. (1997) Convenient method for preparing polystyrene having a beta-hydroxy group: Its application to the synthesis of polyethylene glycol-grafted polystyrene resin. Tetrahedron Lett., 38, 591-594. #8542

329. Paulsen, H., Schleyer, A., Mathieux, N., Meldal, M., & Bock, K. (1997) New solid-phase oligosaccharide synthesis on glycopeptides bound to a solid phase. J. Chem. Soc. Perkin Trans. 1, 281-293. #12522

330. Pavia, M.R. (1997) Compound sourcing:Chemically generated screening libraries - Introduction. In J.P. Devlin (Ed.), High Throughput Screening: The Discovery of Bioactive Substances. (pp. 147-154). Marcel Dekker,Inc., New York. #8992

331. Pearson, W.H., & Clark, R.B. (1997) Solid-phase synthesis of pyrrolidines via 2-azaallyl anion cycloadditions with alkenes. Tetrahedron Lett., 38, 7669-7672. #9675

332. Pehk, T., & Uri, A. (1997) Synthesis and structural characterization of conjugates of adenosine and tetra-aspartate, novel analogs of ATP. Bioorg. Med. Chem. Lett., 7, 2159-2164. #10321

333. Pei, Y., Houghten, R.A., & Kiely, J.S. (1997) Synthesis of 4-amino-3,4-dihydro-2(1H)-quinolinones via beta-lactam intermediates on the solid-phase. Tetrahedron Lett., 38, 3349-3352. #8808

334. Pepito, A.S., & Dittmer, D.C. (1997) Conversion of aziridinemethanol sulfonate esters to allylic amines via tellurium chemistry [review]. J. Org. Chem., 62, 7920-7925. #10322

335. Perry, D.L., Thompson, A.C., Russo, R.E., Mao, X.L., & Chapman, K.L. (1997) Characterization of quaternary metal oxide films by synchrotron X-ray fluorescence microprobe. Appl. Spectrosc., 51, 1781-1783. #10324

336. Peters, J., & Blechert, S. (1997) Cleavage of styrene derivatives from a solid support by ring closing olefin metathesis. Synlett, 348-350. #11399

337. Piettre, S.R., & Baltzer, S. (1997) A new approach to the solid-phase Suzuki coupling reaction. Tetrahedron Lett., 38, 1197-1200. #8601

338. Pirrung, M.C., Chau, J.H.L. & Chen, J. (1997) Indexed combinatorial libraries: Nonoligomeric chemical diversity for the discovery of novel enzyme inhibitors. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 191-206). John Wiley & Sons,Inc., New York. #8358

339. Pirrung, M.C. (1997) Spatially addressable combinatorial libraries. Chem. Rev., 97, 473-488. #8568

340. Piscopio, A.D., Miller, J.F., & Koch, K. (1997) Solid phase heterocyclic synthesis via ring closing metathesis: Traceless linking and cyclative cleavage through a carbon-carbon double bond. Tetrahedron Lett., 38, 7143-7146. #9558

341. Pitsch, S. (1997) An efficient synthesis of enantiomeric ribonucleic acids from D-glucose. Helv. Chim. Acta, 80, 2286-2314. #10328

342. Pivonka, D.E., & Simpson, T.R. (1997) Tools for combinatorial chemistry: Real-time single-bead infrared analysis of a resin-bound photocleavage reaction. Anal. Chem., 69, 3851-3853. #10329

343. Plunkett, M.J., & Ellman, J.A. (1997) Combinatorial chemistry and new drugs. Sci. Amer., 267, 68-73. #9067

344. Plunkett, M.J., & Ellman, J.A. (1997) Germanium and silicon linking strategies for traceless solid-phase synthesis. J. Org. Chem., 62, 2885-2893. #8640

345. Pon, R.T., & Yu, S. (1997) Hydroquinone-O,O'-diacetic acid as a more labile replacement for succinic acid linkers in solid-phase oligonucleotide synthesis. Tetrahedron Lett., 38, 3327-3330. #8639

346. Pon, R.T., & Yu, S. (1997) Rapid automated derivatization of solid-phase supports for oligonucleotide synthesis using uronium or phosphonium coupling reagents. Tetrahedron Lett., 38, 3331-3334. #8638

347. Pon, R.T., & Yu, S. (1997) Hydroquinone-O,O'-diacetic acid ('Q-linker') as a replacement for succinyl and oxalyl linker arms in solid phase oligonucleotide synthesis. Nucl. Acid. Res., 25, 3629-3635. #9344

348. Porco, J.A.Jr., Deegan, T., Devonport, W., Gooding, O.W., Heisler, K., Labadie, J.W., Newcomb, B., Nguyen, C., van Eikeren, P., Wong, J., & Wright, P. (1997) Automated chemical synthesis: From resins to instruments. Mol. Diversity, 2, 197-206. #8867

349. Pothion, C., Paris, M., Heitz, A., Rocheblave, L., Rouch, F., Fehrentz, J.A., & Martinez, J. (1997) Use of ozonolysis in the synthesis of C-terminal peptide aldehydes on solid support. Tetrahedron Lett., 38, 7749-7752. #9679

350. Prien, O., Rolfing, K., Thiel, M., & Kunzer, H. (1997) Combinatorial synthesis of C(2), C(3)-disubstituted 3-hydroxypropionamides utilizing Baylis-Hillman reactions on solid support. Synlett, 325-326. #9149

351. Profenno, L.A., Kierzek, R., Testa, S.M., & Turner, D.H. (1997) Guanosine binds to the tetrahymena ribozyme in more than one step, and its 2'-OH and the nonbridging Pro-S-P phosphoryl oxygen at the cleavage site are required for productive docking. Biochemistry, 36, 12477-12485. #10331

352. Purandare, A.V., & Natarajan, S. (1997) Synthesis of chiral alpha-substituted beta-hydroxy acid derivatives on solid support. Tetrahedron Lett., 38, 8777-8780. #9696

353. Puri, N., Zamaratski, E., Sund, C., & Chattopadhyaya, J. (1997) Synthesis of 5'-polyarene-tethered oligo-DNAs and the termal stability and spectroscopic properties of their duplexes and triplexes. Tetrahedron, 53, 10409-10432. #9445

354. Qabar, M.N., Urban, J., & Kahn, M. (1997) A facile solution and solid phase synthesis of phosphotyrosine mimetic L-4-[diethylphosphono(difluoromethyl)]-phenylalanine (F(2)Pmp(Eto)(2)) derivatives. Tetrahedron, 53, 11171-11178. #9413

355. Rademann, J., & Schmidt, R.R. (1997) Repetitive solid phase glycosylation on an alkyl thiol polymer leading to sugars oligomers containing 1,2-trans- and 1,2-cis-glycosidic linkages. J. Org. Chem., 62, 3650-3653. #10888

356. Radl, S. (1997) Use of combinatorial chemistry and technology in identification of novel bioactive compounds. Drugs Future, 22, 1375-1379. #10537

357. Raju, B., & Kogan, T.P. (1997) Solid phase synthesis of sulfonamides using a carbamate linker. Tetrahedron Lett., 38, 3373-3376. #8811

358. Raju, B., & Kogan, T.P. (1997) Use of halomethyl resins to immobilize amines: An efficient method for synthesis of sulfonamides and amides on a solid support. Tetrahedron Lett., 38, 4965-4968. #9040

359. Ranu, B.C., Saha, M., & Bhar, S. (1997) Surface-mediated solid phase reaction .9. A convenient procedure for aldol reaction of ketene silyl acetals with aldehydes on the solid surface of alumina. Syn. Commun., 27, 3065-3077. #12524

360. Rao, Y.V.S., De Vos, D.E., & Jacobs, P.A. (1997) Practical heterogenisation of an active manganese triazacyclononane epoxydation catalyst via surface glycidylation. J. Chem. Soc. Chem. Commun., 355-356. #9554

361. Rapp, W.E. (1997) Macrobeads as microreactors: New solid-phase synthesis methodology. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 65-94). John Wiley & Sons,Inc., New York. #8353

362. Rasmussen, M.O., Axelsson, O., & Tanner, D. (1997) A practical procedure for the solid-phase synthesis of racemic 2,2'-dihydroxy-1,1'-binaphthyl. Syn. Commun., 27, 4027-4030. #10335

363. Raynaud, F.I., Orr, R.M., Goddard, P.M., Lacey, H.A., Lancashire, H., Judson, I.R., Beck, T., Bryan, B., & Cotter, F.E. (1997) Pharmacokinetics of G3139, a phosphorothioate oligodeoxynucleotide antisense to bcl-2, after intravenous administration or continuous subcutaneous infusion to mice. J. Pharmacol. Exp. Ther., 281, 420-427. #9254

364. Reason, D.C., Wagner, T.C., & Lucas, A.H. (1997) Human fab fragments specific for the Haemophilus influenzae b polysaccharide isolated from a bacteriophage combinatorial library use variable region gene combinations and express an idiotype that mirrors in vivo expression. Infec. Immunity, 65, 261-266. #8254

365. Reddy, M.P., Hanna, N.B., & Farooqui, F. (1997) Ultrafast cleavage and deprotection of oligonucleotides synthesis and use of C-Ac derivatives. Nucleosides Nucleotides, 16, 1589-1598. #10336

366. Richter, L.S., & Desai, M.C. (1997) A TFA-cleavable linkage for solid-phase synthesis of hydroxamic acids. Tetrahedron Lett., 38, 321-322. #8244

367. Riermeier, T.H., Zapf, A., & Beller, M. (1997) Palladium-catalyzed C-C- and C-N-coupling reactions of aryl chlorides. Catal. Lett., 4, 301-309. #10672

368. Rivero, R.A., Greco, M.N. & Maryanoff, B.E. (1997) Equipment for the high-throughput organic synthesis of chemical libraries. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 281-307). American Chemical Society, Washington,DC. #11702

369. Robinson, S., & Roskamp, E.J. (1997) Solid phase synthesis of guanidines. Tetrahedron, 53, 6697-6705. #9118

370. Robles, J., Maseda, M., Beltran, M., Concernau, M., Pedroso, E., & Grandas, A. (1997) Synthesis and enzymatic stability of phosphodiester-linked peptide: Oligonucleotide hybrids. Bioconjug. Chem., 8, 785-788. #10339

371. Rodebaugh, R., Fraser-Reid, B., & Geysen, H.M. (1997) A new o-nitrobenzyl photocleavable linker for solid phase synthesis. Tetrahedron Lett., 38, 7653-7656. #9673

372. Rodebaugh, R., Joshi, S., Fraser-Reid, B., & Geysen, H.M. (1997) Polymer-supported oligosaccharides via N-pentenyl glycosides: Methodology for a carbohydrate library. J. Org. Chem., 62, 5660-5661. #9647

373. Rodriguez, E.C., Winans, K.A., King, D.S., & Bertozzi, C.R. (1997) A strategy for the chemoselective synthesis of O-linked glycopeptides with native sugar-peptide linkages. J. Amer. Chem. Soc., 119, 9905-9906. #10342

374. Rothman, J.H., & Still, W.C. (1997) Peptide-binding antibiotics: A solid-phase assay for screening libraries of vancomycin mimics for selective d-Ala-d-Ala binding. Bioorg. Med. Chem. Lett., 7, 3159-3164. #10344

375. Rottlander, M., & Knochel, P. (1997) Multiple cross-coupling reactions of aryl and benzylic zinc halides with aryl halides and triflates in solid-phase synthesis of polyfunctional aromatics. Synlett, 1084-1086. #10348

376. Rottlander, M., & Knochel, P. (1997) New multi-coupling benzylic zinc reagents for the preparation of flexible aromatic compounds. Tetrahedron Lett., 38, 1749-1752. #8859

377. Roussel, P., Bradley, M., Matthews, I., & Kane, P. (1997) A linker for amidines in solid phase synthesis. Tetrahedron Lett., 38, 4861-4864. #9044

378. Routledge, A., Stock, H.T., Flitsch, S.L., & Turner, N.J. (1997) New fluoride-labile linkers for solid-phase organic synthesis. Tetrahedron Lett., 38, 8287-8290. #9586

379. Routledge, A., Abell, C., & Balasubramanian, S. (1997) An investigation into solid-phase radical chemistry: Synthesis of furan rings. Synlett, 61-62. #9555

380. Routledge, A., Abell, C., & Balasubramanian, S. (1997) The use of a dithiane protected benzoin photolabile safety catch linker for solid-phase synthesis. Tetrahedron Lett., 38, 1227-1230. #8392

381. Rozners, E., & Stromberg, R. (1997) Synthesis and properties of oligoribonucleotide analogs having formacetal internucleoside linkages. J. Org. Chem., 62, 1846-1850. #9169

382. Ruhland, B., Bombrun, A., & Gallop, M.A. (1997) Solid-phase synthesis of 4-arylazetidin-2-ones via Suzuki and Heck cross-coupling reactions. J. Org. Chem., 62, 7820-7826. #10350

383. Sarantakis, D., & Bicksler, J.J. (1997) Solid phase synthesis of sec-amides and removal from the polymeric support under mild conditions. Tetrahedron Lett., 38, 7325-7328. #9570

384. Sardarian, A.R., & Kaboudin, B. (1997) A novel synthesis of diethyl 1-aminoarylmethylphosphonates on the surface of alumina. Tetrahedron Lett., 38, 2543-2546. #8782

385. Sazonova, N.N., Komova, O.V., Rebrov, E.V., Simakov, A.V., Kulikovskaya, N.A., Rogov, V.A., Olikhov, R.V., & Barannik, G.V. (1997) Catalytic and adsorptive properties of a cu-zsm-5 catalyst synthesized by solid-phase method. React. Kinet. Catal. Lett., 60, 313-321. #9093

386. Scarfi, S., Gasparini, A., Damonte, G., & Benatti, U. (1997) Synthesis, uptake, and intracellular metabolism of a hydrophobic tetrapeptide-peptide nucleic acid (PNA)-biotin molecule. Biochem. Biophys. Res. Commun., 236, 323-326. #9366

387. Schow, S.R., Mackman, R.L., Blum, C.L., Brooks, E., Horsma, A.G., Joly, A., Kerwar, S.S., Lee, G., Shiffman, D., Nelson, M.G., Wang, X., Wick, M.M., Zhang, X., & Lum, R.T. (1997) Synthesis and actictivity of 2,6,9-trisubstituted purines. Bioorg. Med. Chem. Lett., 7, 2697-2702. #10035

388. Schuster, M., Lukas, N., & Blechert, S. (1997) Ruthenium catalyzed cross metathesis binding of functionalized olefins to polystyrene resin via a novel allylsilyl linker suitable for electrophilic cleavage. J. Chem. Soc. Chem. Commun., 823-824. #10887

389. Scialdone, M. A., Shuey, S. W., MacDonald, A. A., Newcomb, W. S., and Porco, J. A. Jr. Optimization of urea formation with Phoxime(TM) resin using the Nautilus(TM) 2400. 1997. #12548

390. Scott, R.H., & Balasubramanian, S. (1997) Properties of fluorophores on solid phase resins: Implications for screening, encoding and reaction monitoring. Bioorg. Med. Chem. Lett., 7, 1567-1572. #9513

391. Scott, W.L., Zhou, C., Fang, Z., & O'Donnell, M.J. (1997) The solid phase synthesis of alpha,alpha-disubstituted unnatural amino acids and peptides (di-UPS). Tetrahedron Lett., 38, 3695-3698. #8853

392. Sebastian, D., Heuser, A., Schulze, S., & Waldmann, H. (1997) Selective enzymatic removal of protecting groups from phosphopeptides: Chemoenzymatic synthesis of a characteristic phosphopeptide fragment of the RAF-1 kinase. Synthesis-Stuttgart, 1098-1108. #10356

393. Sebastian, D., & Waldmann, H. (1997) Chemoenzymatic synthesis of a characteristic phosphopeptide fragment of the Raf-I kinase. Tetrahedron Lett., 38, 2927-2930. #9134

394. Seeberger, P.H., Bilodeau, M.T., & Danishefsky, S.J. (1997) Synthesis of biologically important oligosaccharides and other glycoconjugates by the glycal assembly method [review]. Aldrichim. Acta, 30, 75-92. #10499

395. Seeberger, P.H., Beebe, X., Sukenick, G.D., Pochapsky, S., & Danishefsky, S.J. (1997) Monitoring the progress of solid-phase oligosaccharide synthesis by high resolution magic angle spinning NMR: Observations of enhanced selectivity for beta-glycoside formation from aplha-1,2-anhydrosugar donors in solid-phase couplings. Angew. Chem. Int. Ed., 36, 491-493. #9556

396. Seela, F., & Wei, C.F. (1997) Oligonucleotides containing consecutive 2'-deoxyisoguanosine residues - synthesis, duplexes with parallel chain orientation, and aggregation. Helv. Chim. Acta, 80, 73-85. #8387

397. Seela, F., & Leonard, P. (1997) Oligonucleotides with purine nitrogen-7 as glycosylation site. Nucleosides Nucleotides, 16, 669-674. #9420

398. Seela, F., & Chen, Y.M. (1997) Methylated DNA: The influence of 7-deaza-7-methylguanine on the structure and stability of oligonucleotides. Helv. Chim. Acta, 80, 1073-1086. #9460

399. Seela, F., & Leonard, P. (1997) Studies on the base-pairing properties of N-7-(2-deoxy-beta-D-erythro-pentofuranosyl)guanine (N(7)G(d)). Helv. Chim. Acta, 80, 1301-1318. #9462

400. Seitz, O., & Wong, C.H. (1997) Chemoenzymatic solution- and solid-phase synthesis of O-glycopeptides of the mucin domain of madcam-1: A general route to O-lacnac, O-sialyl-lacnac, and O-sialyl-lewis-x peptides [review]. J. Amer. Chem. Soc., 119, 8766-8776. #10357

401. Seitz, O., & Kunz, H. (1997) HYCRON, an allylic anchor for high-efficiency solid phase synthesis of protected peptides and glycopeptides. J. Org. Chem., 62, 813-826. #8389

402. Shah, A., Rahman, S.S., de Biasi, V., & Camilleri, P. (1997) Development of colorimetric method for the detection of amines bound to solid support. Analyst, 122, 325-328. #10570

403. Shapiro, M.J., Chin, J., Marti, R.E., & Jarosinski, M.A. (1997) Enhanced resolution in MAS NMR for combinatorial chemistry. Tetrahedron Lett., 38, 1333-1336. #8378

404. Shapiro, M.J., Lin, M. & Yan, B. (1997) On-resin analysis in combinatorial chemistry. In A.W. Czarnik & S.H. DeWitt (Eds.), A Practical Guide to Combinatorial Chemistry. (pp. 123-151). American Chemical Society, Washington,DC. #10017

405. Sharma, S., & Pasha, S. (1997) Rapid anchoring of cesium salts of Boc-protected amino acids on chloromethyl polystyrene resin using dibenzo-18-crown-6 as a catalyst. Bioorg. Med. Chem. Lett., 7, 2077-2080. #10359

406. Shchepinov, M.S., & Stetsenko, D.A. (1997) A facile route to 3'-modified oligonucleotides. Bioorg. Med. Chem. Lett., 7, 1181-1184. #9210

407. Short, K.M., & Mjalli, A.M.M. (1997) A solid-phase combinatorial method for the synthesis of novel 5- and 6-membered ring lactams. Tetrahedron Lett., 38, 359-362. #8526

408. Short, K.M., Ching, B.W., & Mjalli, A.M.M. (1997) Exploitation of the Ugi 4CC reaction: Preparation of small molecule combinatorial libraries via solid phase. Tetrahedron, 53, 6653-6679. #8635

409. Shuttleworth, S.J., Allin, S.M., & Sharma, P.K. (1997) Functionalised polymers: Recent developments and new applications in synthetic organic chemistry [review]. Synthesis-Stuttgart, 1217-1239. #10363

410. Sibi, M.P., & Chandramouli, S.V. (1997) Intermolecular free radical reactions on solid support. Allylation of esters. Tetrahedron Lett., 38, 8929-8932. #9859

411. Smith, J., & Cooper, T. (1997) Combinatorial synthesis in medicinal chemistry: Implications in drug discovery and development. Epitheor. Klin. Farmacol. Farmakokinet. ,Int. Ed., 11, 104-107. #10531

412. Smith, S.A., & Mclaughlin, L.W. (1997) Probing contacts to the DNA backbone in the Trp repressor-operator sequence-specific protein-nucleic acid complex using diastereomeric methylphosphonate analogues. Biochemistry, 36, 6046-6058. #9212

413. Song, A.I., & Rana, T.M. (1997) Synthesis of an amino acid analogue to incorporate p-aminobenzyl-EDTA in peptides. Bioconjug. Chem., 8, 249-252. #9276

414. Spitzer, J.L., Kurth, M.J., Schore, N.E., & Najdi, S.D. (1997) Polymer-supported synthesis as a tool for improving chemoselectivity: Pauson-Khand reaction. Tetrahedron, 53, 6791-6908. #12117

415. Stec, W.J., Wozniak, L.A., Pyzowski, J., & Niewiarowski, W. (1997) Novel cost-effective methanephosphonoanilidothioate approach to the stereoselective synthesis of dinucleoside (3',5')-methanephosphonates. Antisense Nucl. Acid Drug Devel., 7, 381-395. #10374

416. Stephensen, H., & Zaragoza, F. (1997) Resin-bound isothiocyanates and their synthetic equivalents as intermediates for the solid-phase synthesis of substituted thiophenes. J. Org. Chem., 62, 6096-6097. #9325

417. Stranix, B.R., Liu, H.Q., & Darling, G.D. (1997) Functional polymers from (vinyl)polystyrene: Recyclable polymer-supported organosilicon protecting groups for solid-phase synthesis. J. Org. Chem., 62, 6183-6186. #10377

418. Stranix, B.R., Gao, J.P., Barghi, R., Salha, J., & Darling, G.D. (1997) Functional polymers from (vinyl)polystyrene. Short routes to binding functional groups to polystyrene resin through a dimethylene spacer: Bromine, sulfur, phosphorus, silicon, hydrogen, boron, and oxygen. J. Org. Chem., 62, 8987-8993. #9736

419. Sucholeiki, I. (1997) Selection of supports for solid-phase organic synthesis. In W.H. Moos, M.R. Pavia, B.K. Kay & A.D. Ellington (Eds.), Annual Reports in Combinatorial Chemistry and Molecular Diversity. (pp. 41-49). ESCOM, Leiden. #8615

420. Sucholeiki, I. (1997) Solid-phase methods in combinatorial chemistry. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 119-134). John Wiley & Sons,Inc., New York. #8355

421. Suhara, Y., Izumi, M., Ichikawa, M., Penno, M.B., & Ichikawa, Y. (1997) Peptide-sugar hybrids: Like peptide, like oligosaccharide. Tetrahedron Lett., 38, 7167-7170. #9561

422. Sun, S.G., Piccirilli, J.A., & Yoshida, A. (1997) Synthesis of 3'-thioribonucleosides and their incorporation into oligoribonucleotides via phosphoramidite chemistry. RNA Publ. RNA Soc., 3, 1352-1363. #9927

423. Sutherlin, D.P., & Armstrong, R.W. (1997) Synthesis of 12 stereochemically and structurally diverse C-trisaccharides [Review]. J. Org. Chem., 62, 5267-5283. #9414

424. Swali, V., Wells, N.J., Langley, G.J., & Bradley, M. (1997) Solid-phase dendrimer synthesis and the generation of super-high-loading resin beads for combinatorial chemistry. J. Org. Chem., 62, 4902-4903. #9301

425. Swayze, E.E. (1997) Secondary amide-based linkers for solid phase organic synthesis. Tetrahedron Lett., 38, 8465-8468. #9582

426. Swayze, E.E. (1997) The solid phase synthesis of trisubstituted 1,4-diazabicyclo[4.3.0]nonan-2-one scaffolds: On bead monitoring of heterocycle forming reactions using (15)N NMR. Tetrahedron Lett., 38, 8643-8646. #9694

427. Sylvain, C., Wagner, A., & Mioskowski, C. (1997) Ozone: A versatile reagent for solid phase synthesis. Tetrahedron Lett., 38, 1043-1044. #8409

428. Szardenings, A.K., Burkoth, T.S., Lu, H.H., Tien, D.W., & Campbell, D.A. (1997) A simple procedure for the solid phase synthesis of diketopiperazine and diketomorpholine derivatives. Tetrahedron, 53, 6573-6593. #9113

429. Szokan, G., Almas, M., Krizsan, K., Khlafulla, A.R., Tyihak, E., & Szende, B. (1997) Structure determination and synthesis of lysine isopeptides influencing on cell proliferation. Biopolymers, 42, 305-318. #9346

430. Tardy-Planechaud, S., Fujimoto, J., Lin, S.S., & Sowers, L.C. (1997) Solid phase synthesis and restriction endonuclease cleavage of oligodeoxynucleotides containing 5-(hydroxymethyl)-cytosine. Nucl. Acid. Res., 25, 553-558. #8403

431. Taylor, C.M. (1997) Strategies for combinatorial libraries of oligosaccharides. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 207-224). John Wiley & Sons,Inc., New York. #8359

432. Teerhuis, N.M., Hiemstra, H., & Speckamp, W.N. (1997) Synthesis of enantiopure (nor-)azatropanes via N-acylhydrazonium ion intermediates. Tetrahedron Lett., 38, 155-158. #8608

433. Tempest, P.A., & Armstrong, R.W. (1997) Cyclobutenedione derivatives on solid support: Toward multiple core structure libraries. J. Amer. Chem. Soc., 119, 7607-7608. #10444

434. Terrett, N.K., Gardner, M., Gordon, D.W., Kobylecki, R.J., & Steele, J. (1997) Drug discovery by combinatorial chemistry: The development of a novel method for the rapid synthesis of single compounds. Chem. Eur. J., 3, 1917-1920. #10388

435. Thibon, J., Latxague, L., & Deleris, G. (1997) Synthesis of silicon analogues of acyclonucleotides incorporable in oligonucleotide solid-phase synthesis. J. Org. Chem., 62, 4635-4642. #9468

436. Tholey, A., & Hoffmann, B. (1997) Solid-phase synthesis of tyrosyl H-phosphonopeptides and methylphosphonopeptides. J. Peptide Sci., 3, 186-192. #9890

437. Tietze, L.F., Steinmetz, A., & Balkenhohl, F. (1997) Solid-phase synthesis of polymer-bound beta-ketoesters and their application in the synthesis of structurally diverse pyrazolones. Bioorg. Med. Chem. Lett., 7, 1303-1306. #9191

438. Toemoeskoezi, I., & Oetvoes, L. (1997) Stereospecific synthesis of P-chiral oligonucleotide analogs. Hung. Magy. Kem. Lapja, 52, 28-31. #8462

439. Tomatis, R., Marastoni, M., Balboni, G., Guerrini, R., Capasso, A., Sorrentino, L., Santagada, V., Caliendo, G., Lazarus, L.H., & Salvadori, S. (1997) Synthesis and farmacological activity of deltorphin and dermorphin-related glycopeptides. J. Med. Chem., 40, 2948-2952. #9347

440. Tomkinson, N.C.O., Sefler, A.M., Plunket, K.D., Blanchard, S.G., Parks, D.J., & Willson, T.M. (1997) Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARgamma ligands. Bioorg. Med. Chem. Lett., 7, 2491-2496. #9988

441. Tonks, L., Anson, M.S., Hellgardt, K., Mirza, A.R., Thompson, D.F., & Williams, J.M.J. (1997) Palladium catalyzed Heck reactions and allylic substitution reactions using glass bead technology. Tetrahedron Lett., 38, 4319-4322. #8701

442. Torres, J.L., & Clapes, P. (1997) Neoglycopeptide synthesis and purification in multi-gram scale: Preparation of O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-N-alpha-fluoren-9-yl-methoxycarbonyl-hydroxyproline and its use in the pilot-scale synthesis of the potent analgesic glycopeptide 01.5-beta-D-galactopyranosyl[DMet2,Hyp5]enkephalinamide. J. Peptide Sci., 3, 99-109. #9946

443. Turner, N.J. (1997) The application of enzymes in the synthesis of amino acids, peptides and carbohydrates. Trudy Vsesoyuznogo Nauchno-Issledovatel'Skogo Instituta Zhivotnovodstva, 1, 21-36. #10393

444. Valentijn, A.R.P.M., van der Marel, G.A., Sliedregt, L.A.J.M., van Berkel, T.J.C., Biessen, E.A.L., & van Boom, J.H. (1997) Solid-phase synthesis of lysine-based cluster galactosides with high affinity for the asialoglycoprotein receptor. Tetrahedron, 53, 759-770. #8267

445. Van Ausdall, D. A. and Marshall, W. S. Automated high throughput mass spectral analysis of oligonucleotides. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.116 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8290

446. Van den Ancker, T.R., Hanson, G.R., Lee, F.C., & Raston, C.L. (1997) Polymer supported alkali metal naphthalenides: Application in the generation of lithium and sodium reagents. J. Chem. Soc. Chem. Commun., 125-126. #8546

447. van der Laan, A.C., Brill, R., Kuimelis, R.G., Kuyl-Yeheskiely, E., van Boom, J.H., Andrus, A., & Vinayak, R. (1997) A convenient automated solid-phase synthesis of PNA-(5' )-DNA-(3' )-PNA chimera. Tetrahedron Lett., 38, 2249-2252. #8650

448. Vinayak, R., van der Laan, A.C., Brill, R., Otteson, K., Andrus, A., Kuyl-Yeheskiely, E., & van Boom, J.H. (1997) Automated chemical preparation of PNA and PNA-DNA chimera on nucleic acid synthesizer. Nucleosides Nucleotides, 16, 1653-1656. #9858

449. Virgilio, A.A., Bray, A.A., Zhang, W., Trinh, L., Snyder, M., Morrissey, M.M., & Ellman, J.A. (1997) Synthesis and evaluation of a library of peptidomimetics based upon the beta-turn. Tetrahedron, 53, 6635-6644. #9300

450. Vlattas, I., Dellureficio, J., Dunn, R., Sytwu, I.I., & Stanton, J. (1997) The use of thioesters in solid phase organic synthesis. Tetrahedron Lett., 38, 7321-7324. #9569

451. Vo, N.H., Eyermann, C.J., & Hodge, C.N. (1997) Transformation of resin-bound pyridinium ylides: I. A stereoselective synthesis of 2,2,3-trisubstituted cyclopropanecarboxylates. Tetrahedron Lett., 38, 7951-7954. #9688

452. von dem Bussche-Hunnefeld, C., Balkenhohl, F., Lansky, A., & Zechel, C. (1997) Combinatorial chemistry. Fresenius J. Anal. Chem., 359, 3-9. #10403

453. Wada, T., Sato, Y., Honda, F., Kawahara, S., & Sekine, M. (1997) Chemical synthesis of oligodeoxyribonucleotides using N-unprotected H-phosphonate monomers and carbonium and phosphonium condensing reagents: O-Selective phosphonylation and condensation [review]. J. Amer. Chem. Soc., 119, 12710-12721. #10404

454. Waldmann, H., & Reidel, A. (1997) The phenylacetyl group: The first amino protecting group that can be removed enzymatically from oligonucleotides in solution and on a solid support. Angew. Chem. Int. Ed., 36, 647-649. #12502

455. Waldmann, H., & Gabold, S. (1997) Chemoenzymatic synthesis of nucleopeptides. Chem. Commun., 1861-1862. #10405

456. Wallace, O.B. (1997) Solid phase synthesis of ketones from esters. Tetrahedron Lett., 38, 4939-4942. #9037

457. Wallberg, A., Weigelt, D., Falk, N., & Magnusson, G. (1997) A 2-silylethanol-based anomeric linker for carbohydrates: Transformation into 1-O-acyl derivatives. Tetrahedron Lett., 38, 4285-4286. #10084

458. Walsh, A.J., Clark, G.C., & Fraser, W. (1997) A direct and efficient method for derivatisation of solid supports for oligonucleotide synthesis. Tetrahedron Lett., 38, 1651-1654. #8862

459. Wang, F., & Hauske, J.R. (1997) Solid-phase synthesis of 3,4-dihydroquinazoline. Tetrahedron Lett., 38, 8651-8654. #9693

460. Wang, F., & Hauske, J.R. (1997) Solid-phase synthesis of benzoxazoles via Mitsunobu reaction. Tetrahedron Lett., 38, 6529-6532. #9323

461. Wang, G.T., Chen, Y., Wang, S., Sciotti, R., & Sowin, T. (1997) Solid phase synthesis of ureas of secondary amines via carbamoyl chloride. Tetrahedron Lett., 38, 1895-1898. #8609

462. Wang, J.C., & Just, G. (1997) A stereoselective synthesis of dinucleotide phosphorothioates, using chiral indol-oxazaphosphorine intermediates. Tetrahedron Lett., 38, 3797-3800. #9055

463. Wang, Y., & Wilson, S.R. (1997) Solid phase synthesis of 2,3-dihydro-4-pyridones: Reaction of Danishefsky's diene with polymer-bound imines. Tetrahedron Lett., 38, 4021-4024. #9049

464. Watson, S.P., Wilson, R.D., Judd, D.B., & Richards, S.A. (1997) Solid phase synthesis of 5-aminopyrazoles and derivatives. Tetrahedron Lett., 38, 9065-9068. #9864

465. Weiler, J., & Hoheisel, J.D. (1997) Combining the preparation of oligonucleotide arrays and synthesis of high-quality primers. Anal. Biochem., 243, 218-227. #9373

466. Wen, J.J., & Spatola, A.F. (1997) A systematic approach to the solid-phase synthesis of linear and cyclic pseudopeptide libraries containing psi[CH2NH]amide bond surrogates. J. Pept. Res., 49, 3-14. #8641

467. Wenninger, D., & Seliger, H. (1997) Synthesis and hybridization properties of modified oligonucleotides with PNA-DNA dimer blocks. Nucleosides Nucleotides, 16, 977-980. #10413

468. Wenzel, T., & Nair, V. (1997) Novel oligodeoxyribonucleotides incorporating L-related isodeoxynucleosides: Solid phase synthesis, enzymology, and CD studies. Bioorg. Med. Chem. Lett., 7, 3195-3198. #10414

469. Whitehouse, D.L., Nelson, K.H.Jr., Savinov, S.N., & Austin, D.J. (1997) A chemoselective rhodium(II) mediated solid phase 1,3-dipolar cycloaddition and its application to a thermally self-cleaving furan scaffold. Tetrahedron Lett., 38, 7139-7142. #9557

470. Whitehouse, D.L., Savinov, S.N., & Austin, D.J. (1997) An improved synthesis and selective coupling of a hydroxy based photolabile linker for solid phase organic synthesis. Tetrahedron Lett., 38, 7851-7852. #9616

471. Willems, H. (1997) New combinatorial chemistry. Drug Disc. Today, 2, 214-217. #9199

472. Wilson, C.J., Husain, S.S., Stimson, E.R., Dangott, L.J., Miller, K.W., & Maggio, J.E. (1997) p-(4-Hydroxybenzoyl)phenylalanine: A photoreactive amino acid analog amenable to radioiodination for elucidation of peptide-protein interaction application to substance P receptor. Biochemistry, 36, 4542-4551. #9257

473. Wilson, S.R. (1997) Introduction to combinatorial libraries: Concepts and terms. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 1-24). John Wiley & Sons,Inc., New York. #8350

474. Wipf, P., Cunningham, A., Rice, R.L., & Lazo, J.S. (1997) Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors. Bioorg. Med. Chem., 5, 165-177. #9342

475. Wipf, P., & Henninger, T.C. (1997) Solid-phase synthesis of peptide mimetics with (E)-alkene amide bond replacements derived from alkenylaziridines. J. Org. Chem., 62, 1586-1587. #9168

476. Woolard, F.X., Paetsch, J., & Ellman, J.A. (1997) A silicon linker for direct loading of aromatic compounds to supports. Traceless synthesis of pyridine-based tricyclics. J. Org. Chem., 62, 6102-6103. #10442

477. Wu, M.H., & Jacobsen, E.N. (1997) An efficient formal synthesis of balanol via the asymmetric epoxide ring opening reaction. Tetrahedron Lett., 38, 1693-1696. #8858

478. Xiao, X., Zhao, C., Potash, H., & Nova, M.P. (1997) Combinatorial chemistry with laser optical encoding. Angew. Chem. Int. Ed., 36, 780-782. #8726

479. Xiao, X.Y., Parandoosh, Z., & Nova, M.P. (1997) Design and synthesis of a taxoid library using radiofrequency encoded combinatorial chemistry. J. Org. Chem., 62, 6029-6033. #10421

480. Xiao, X.Y., Ngu, K., Chao, C., & Patel, D.V. (1997) Selective solid phase synthesis of ureas and hydantoins from common phenyl carbamate intermediates. J. Org. Chem., 62, 6968-6973. #10420

481. Xiao, X.Y. & Nova, M.P. (1997) Radiofrequency encoding and additional techniques for the structure elucidation of synthetic combinatorial libraries. In S.R. Wilson & A.W. Czarnik (Eds.), Combinatorial Chemistry. Synthesis and Application. (pp. 135-152). John Wiley & Sons,Inc., New York. #8356

482. Xu, J., & Ma, Y. (1997) Simultaneous multiple organic synthesis. Huaxue Tongbao, 1-8. #8652

483. Xu, Q., Chao, B., Wang, Y., & Dittmer, D.C. (1997) Tellurium in the "no-solvent" organic synthesis of allylic alcohols. Tetrahedron, 53, 12131-12146. #9328

484. Yamada, H., Imamura, K., & Takahashi, T. (1997) Synthesis of a branched oligosaccharide by remote glycosidation. Tetrahedron Lett., 38, 391-394. #8245

485. Yamada, K., Fujita, E., & Nishimura, S.I. (1997) High performance polymer supports for enzyme-assisted synthesis of glycoconjugates. Carbohyd. Res., 305, 443-461. #10943

486. Yamaguchi, T., Saneyoshi, M., Tomikawa, A., Kohgo, S., Narita, K., & Suyama, K. (1997) Synthesis and evaluation of oligodeoxyribonucleotides containing an aryl(trifluoromethyl)diazirine moiety as the cross-linking probe: Photoaffinity labeling of mammalian DNA polymerase beta. Nucl. Acid. Res., 25, 2352-2358. #9949

487. Yan, B. (1997) Monitoring the progression of organic reactions on solid supports. Recent Res. Dev. Org. Chem., 1, 55-65. #10018

488. Yan, B., & Li, W. (1997) Rapid fluorescence determination of the absolute amount of aldehyde and ketone groups on resin supports. J. Org. Chem., 62, 9354-9357. #9856

489. Yan, B., & Sun, Q. (1997) Crucial factors regulating site interactions in resin supports determined by single bead IR. J. Org. Chem., 63, 55-58. #10016

490. Yang, L., & Chiu, K. (1997) Solid phase synthesis of Fmoc N-methyl amino acids: Application of the Fukuyama amine synthesis. Tetrahedron Lett., 38, 7307-7310. #9568

491. Yang, X., Misiura, K., Sochacki, M., & Stec, W.J. (1997) Deoxyxylothymidine 3'-O-phosphorothioates: Synthesis, stereochemistry and stereocontrolled incorporation into oligothymidylates. Bioorg. Med. Chem. Lett., 7, 2651-2656. #10427

492. Yokomatsu, T., Murano, T., Suemune, K., & Shibuya, S. (1997) Facile synthesis of aryl(difluoromethyl)phosphonates through CuBr: Mediated cross coupling reactions of [(diethoxyphosphinyl)difluoromethyl]zinc bromide with aryl iodides. Tetrahedron, 53, 815-822. #8265

493. Yokum, T.S., Tungaturthi, P.K., & McLaughlin, M.L. (1997) Benz[f]tryptophan, a bathochromic analog of tryptophan, synthesis of its N-alpha-t-Boc derivative. Tetrahedron Lett., 38, 5111-5114. #9033

494. Yoo, S.E., Seo, J.S., Yi, K.Y., & Gong, Y.D. (1997) Solid phase synthesis of biphenyltetrazole derivatives. Tetrahedron Lett., 38, 1203-1206. #8391

495. Yoo, Y.S., Han, Y.S., Suh, M.J., & Park, J. (1997) Analysis of phosphopeptides by capillary electrophoresis and matrix-assisted laser-desorption ionization time-of-flight mass spectrometry. J. Chromatogr., 763, 285-293. #9147

496. Yoshikawa, M., Izumi, J., & Kitao, T. (1997) Enantioselective electrodialysis of amino acids with charged polar side chains through molecularly imprinted polymeric membranes containing dide derivatives. Polym. J., 29, 205-210. #9148

497. Youngman, M.A., & Dax, S.L. (1997) Mannich reactions of a resin-bound terminal alkyne. Tetrahedron Lett., 38, 6347-6350. #9320

498. Zanini, D., & Roy, R. (1997) Chemoenzymatic synthesis and lectin binding properties of dendritic N-acetyllactosamine. Bioconjug. Chem., 8, 187-192. #9370

499. Zaragoza, F. (1997) Solid phase synthesis of cyanoacetamidines: Fast access to potential bioisosteres of acceptor-substituted guanidines. Tetrahedron Lett., 38, 7291-7294. #9566

500. Zenie, F. H. It's only a matter of time. In: Anonymous. (Eds.) Zymark Corporation, Hopkington, MA p.15 Proceedings of the International Symposium on Laboratory Automation and Robotics 1996. #8280

501. Zhang, H.C., & Maryanoff, B.E. (1997) Construction of indole and benzofuran systems on the solid phase via palladium-mediated cyclizations. J. Org. Chem., 62, 1804-1809. #8466

502. Zhang, H.C., Brumfield, K.K., & Maryanoff, B.E. (1997) Synthesis of trisubstituted indoles on the solid phase via palladium-mediated heteroannulation of internal alkynes. Tetrahedron Lett., 38, 2439-2442. #8778

503. Zhang, X.H., Jones, R.A., & Gaffney, B.L. (1997) RNA synthesis using a universal, base-stable allyl linker. Nucl. Acid. Res., 25, 3980-3983. #9928

504. Zhao, X.Y., Jung, K.W., & Janda, K.D. (1997) Soluble polymer synthesis: An improved traceless linker methodology for aliphatic C-H bond formation. Tetrahedron Lett., 38, 977-980. #8659

505. Zubin, E.M., Antsypovich, S.I., Oretskaya, T.S., Romanova, E.A., Volkov, E.M., Tashlitskii, V.N., & Shabarova, Z.A. (1997) Synthesis of modified oligodeoxyribonucleotides containing 9-(2'-amino-2'-deoxy-beta-D-arabinofuranosyl)adenine [russian]. Bioorganicheskaia Khimiia, 23, 809-816. #10437