Papers on solid phase organic synthesis published in 1996

This list is arranged by the name of the first author. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (michal@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M., Leblova Z.: Dynamic database of references in molecular diversity. Internet http://www.5z.com.

Recently added entries are marked in bold

1. Acevedo, O.L., & Andrews, R.S. (1996) Synthesis of propane-2,3-diol combinatorial monomers. Tetrahedron Lett., 37, 3931-3934. #4601

2. Adamczyk, M., & Fishpaugh, J.R. (1996) A solid supported synthesis of thiol esters. Tetrahedron Lett., 37, 4305-4308. #4983

3. Adamczyk, M., & Fishpaugh, J.R. (1996) Expeditious synthesis of Mosher amides using a solid supported carbodiimide. Tetrahedron Lett., 37, 7171-7172. #5527

4. Adinolfi, M., Barone, G., De Napoli, L., Iadonisi, A., & Piccialli, G. (1996) Solid phase synthesis of oligosaccharides. Tetrahedron Lett., 37, 5007-5010. #4905

5. Allin, S.M., & Shuttleworth, S.J. (1996) The preparation and first application of a polymer-supported "Evans" oxazolidines. Tetrahedron Lett., 37, 8023-8026. #5753

6. Alvarado Urbina, G., Voelter, W., Weiler, A., Echner, H., Stoeva, S., Schernthaner, J.P., Reinig, W., Glubler, G. & Gross, W. (1996) Optimized automated solid phase synthesis of oligonucleotides and their derivatives. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 135-140). Mayflower Scientific Limited, Birmingham. #8913

7. Appell, K.C., Chung, T.D.Y., Ohlmeyer, M.H.J., Sigal, N.H., Baldwin, J.J., & Chelsky, D. (1996) Biological screening of a large combinatorial library. J. Biomol. Screen., 1, 27-31. #10039

8. Armstrong, R.W., Tempest, P.A., & Cargill, J.F. (1996) Microchip encoded combinatorial libraries. Generation of a spatially encoded library from a pool synthesis. Chimia, 50, 258-260. #5857

9. Atuegbu, A., Maclean, D., Nguyen, C., Gordon, E.M., & Jacobs, J.W. (1996) Combinatorial modification of natural products: Preparation of unencoded and encoded libraries of Rauwolfia alkaloids. Bioorg. Med. Chem., 4, 1097-1106. #4896

10. Backes, B.J., Virgilio, A.A., & Ellman, J.A. (1996) Activation method to prepare a highly reactive acylsulfonamide "safety-catch" linker for solid-phase synthesis. J. Amer. Chem. Soc., 118, 3055-3056. #4137

11. Baird, E.E., & Dervan, P.B. (1996) Solid phase synthesis of polyamides containing imidazole and pyrrole amino acids. J. Amer. Chem. Soc., 118, 6141-6146. #4829

12. Baldwin, J.J. (1996) Solid phase chemistry in combinatorial library construction. In Anonymous, Book of Abstracts, 212th ACS National Meeting, Orlando, FL, August 25-29. (pp. ORGN-158. American Chemical Society,Washington,D, #5894

13. Baldwin, J.J., & Henderson, I. (1996) Recent advances in the generation of small-molecule combinatorial libraries: Encoded split synthesis and solid-phase synthetic methodology. Med. Res. Rev., 16, 391-405. #5281

14. Balkenhohl, F., von dem Bussche-Hunnefeld, C., Lansky, A., & Zechel, C. (1996) Combinatorial synthesis of small organic molecules. Angew. Chem. Int. Ed., 35, 2289-2337. #5694

15. Barn, D.R., Morphy, J.R., & Rees, D.C. (1996) Synthesis of an array of amides by aluminium chloride assisted cleavage of resin-bound esters. Tetrahedron Lett., 37, 3213-3216. #4746

16. Beaver, K.A., Siegmund, A.C., & Spear, K.L. (1996) Application of the sulfonamide functional group as an anchor for solid phase organic synthesis (SPOS). Tetrahedron Lett., 37, 1145-1148. #3882

17. Berg, R.H., Hvilsted, S., & Ramanujam, P.S. (1996) Peptide oligomers for holographic data storage. Nature, 383, 505-508. #5956

18. Bicknell, A.J., & Hird, N.W. (1996) Synthesis of a highly functionalized rigid template by solid-phase azomethine ylide cycloadditon. Bioorg. Med. Chem. Lett., 6, 2441-2444. #5750

19. Bilodeau, M.T., & Danishefsky, S.J. (1996) Glycals in organic synthesis: The evolution of comprehensive strategies for the assembly of oligosaccharides and glycoconjugates of biological consequence. Angew. Chem. Int. Ed., 35, 1380. #14281 NEWOLD

20. Boas, U., Heegaard, P. & Jacobsen, M.H. (1996) Solid phase coupling of unprotected reducing carbohydrates to the N-terminus of peptides. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 327-328). Mayflower Scientific Limited, Birmingham. #8943

21. Boehm, T.L. & Showalter, H.D.H. (1996) Development of a silicon-based traceless linker for solid-phase organic synthesis. In Anonymous, Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28. (pp. BIOT-121. American Chemical Society,Washington,D, #6004

22. Boehm, T.L., & Showalter, H.D.H. (1996) Development of a novel silyl ether linker for solid-phase organic synthesis. J. Org. Chem., 61, 6498-6499. #5392

23. Bolton, G.L. (1996) Solid phase synthesis of azabicyclo[4.3.0]nonen-8-one amino acid derivatives via intramolecular Pauson-Khand cyclization. Tetrahedron Lett., 37, 3433-3436. #4574

24. Bondy, S., Cheng, S., Saunders, J., Tarby, C., & Wheeler, K. (1996) Molecular diversity and solid-phase synthesis. Drug Disc. Today, 1, 132-133. #6010

25. Bonnat, M., Bradley, M., & Kilburn, J.D. (1996) The solid phase synthesis of a guanidinium based 'tweezer' receptor. Tetrahedron Lett., 37, 5409-5412. #5086

26. Borman, S. (1996) Unnatural peptide synthesis automated. C&EN, 32-32. #4928

27. Borman, S. (1996) Combinatorial chemists focus on small molecules, molecular recognition, and automation. C&EN, 74, 29-54. #4611

28. Boyd, E.A., Chan, W.C., & Loh, V.M.J. (1996) Multiple solid phase synthesis of (RS)-1-aminophosphinic acids. Tetrahedron Lett., 37, 1647-1650. #4061

29. Breipohl, G., Will, D.W., Langner, D., Knolle, J. & Uhlmann, E. (1996) Synthesis of polyamide nucleic acids using a new protection scheme which is fully compatible with oligonucleotide synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 61-64). Mayflower Scientific Limited, Birmingham. #8899

30. Broddefalk, J., Bergquist, K.E., & Kihlberg, J. (1996) Preparation of a glycopeptide analogue of type II collagen use of acid labile protective groups for carbohydrate moieties in solid phase synthesis of O-linked glycopeptides. Tetrahedron Lett., 37, 3011-3014. #6052

31. Brown, J.M., & Ramsden, J.A. (1996) Supports for solid-phase synthesis with high fluidity and high functionality. J. Chem. Soc. Chem. Commun., 2117-2118. #8533

32. Brown, R. (1996) Recent developments in solid-phase organic synthesis. Contemp. Org. Synt., 216-237. #9600

33. Brummel, C.L., Vickerman, J.C., Carr, S.A., Hemling, M.E., Roberts, G.D., Johnson, W., Weinstock, J., Gaitanopoulos, D., Benkovic, S.J., & Winograd, N. (1996) Evaluation of mass spectrometric methods applicable to the direct analysis of non-peptide bead-bound combinatorial libraries. Anal. Chem., 68, 237-242. #3927

34. Buckman, B.O., & Mohan, R. (1996) Solid-phase synthesis of 1,3-dialkyl quinazoline-2,4-diones. Tetrahedron Lett., 37, 4439-4442. #4798

35. Bunin, B.A., Plunkett, M.J. & Ellman, J.A. (1996) Synthesis and evaluation of three 1,4-benzodiazepine libraries. In G. Jung (Ed.), Combinatorial Peptide and Nonpeptide Libraries: A Handbook. (pp. 405-424). VCH, Weinheim. #2160

36. Bunin, B.A., Plunkett, M.J., & Ellman, J.A. (1996) Synthesis and evaluation of 1,4-benzodiazepine libraries. Methods Enzymol., 267, 448-466. #3671

37. Burgess, K., Shin, H. & Totani, R. (1996) Methodology for syntheses of ureas libraries. In Anonymous, Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28. (pp. ORGN-279. American Chemical Society,Washington,D, #6080

38. Cao, X., & Mjalli, A.M.M. (1996) Combinatorial method for the synthesis of a-hydroxy phosphonates on Wang resin. Tetrahedron Lett., 37, 6073-6076. #5227

39. Cargill, J.F., & Maiefski, R.R. (1996) Automated combinatorial chemistry on solid phase. Lab. Robotics Automation, 8, 139-148. #5344

40. Case-Green, S.C., Mir, K.U., Milner, N. & Southern, E.M. (1996) Synthesis and applications of spatially addressable oligonucleotide arrays. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 57-60). Mayflower Scientific Limited, Birmingham. #8898

41. Cernerud, M., Reina, J.A., Tegenfeldt, J., & Moberg, C. (1996) Chiral polymers via asymmetric epoxidation and asymmetric dihydroxylation. Tetrahedron:Asymmetry, 7, 2863-2870. #8534

42. Chabala, J.C., Baldwin, J.J., Burbaum, J.J., Chelsky, D., Dillard, L.W., Henderson, I., Li, G., Ohlmeyer, M.H.J., Randle, T.L., Reader, J.C., Rokosz, L. & Sigal, N.H. (1996) Synthesis of binary encoded small molecule libraries and their application to drug discovery and optimization. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 101-106). Mayflower Scientific Limited, Birmingham. #8905

43. Chaiken, I., Myszka, D., & Morton, T. (1996) New opportunities for using immobilized ligands to characterize macromolecular recognition and design recognition molecules. Adv. Mol. Cell Biol., 15B, 553-568. #8649

44. Chan, T.Y., Chen, A., Allanson, N., Chen, R., Liu, D., & Sofia, M.J. (1996) Solid phase synthesis of peptidoglycan monomers for the generation of a combinatorial library. Tetrahedron Lett., 37, 8097-8100. #5747

45. Chan, T.Y., Chen, A., Allanson, N., Chen, R., Liu, D. & Sofia, M.J. (1996) Solid supported glycopeptide synthesis for the construction of a glycopeptide combinatorial library. In Anonymous, Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28. (pp. MEDI-198. American Chemical Society,Washington,D, #6143

46. Chiron, S., Torres, J.A., Fernandes-Alba, A., Alpendurada, M.F., & Barcelo, D. (1996) Identification of carbofuran and methiocarb and their transformation products in estuarine waters by online solid phase extraction liquid chromatography-mass spectrometry. Int. J. Environ. Anal. Chem., 65, 37-52. #8461

47. Choong, I.C., & Ellman, J.A. (1996) Solid-phase synthesis: Applications to combinatorial libraries. Annu. Rep. Med. Chem., 31, 309-318. #8134

48. Chucholowski, A., Masquelin, T., Obrecht, D., Stadlwieser, J., & Villalgordo, J.M. (1996) Novel solution- and solid-phase strategies for the parallel and combinatorial synthesis of small-molecular-weight compound libraries. Chimia, 50, 525-530. #8188

49. Cole, B.M., Shimizu, K.D., Krueger, C.A., Harrity, J.P.A., Snapper, M.L., & Hoveyda, A.H. (1996) Discovery of chiral catalysts through ligand diversity: Ti-catalyzed enantioselective addition of TMSCN to meso epoxides. Angew. Chem. Int. Ed., 35, 1668-1671. #5273

50. Cook, P.D., Kiely, J.S., & Sprankle, K. (1996) C.C.U. ISIS Pharmaceuticals Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis. US Patent. 5,539,083. 200,742, #12296

51. Crespin, M.A., Ballesteros, E., Gallero, M., & Valcarcel, M. (1996) Automatic preconcentration of chlorophenols and gas chromatographic determination with electron capture detection. Chromatographia, 43, 633-639. #8468

52. Czarnik, A.W., & DeWitt, S.H. (1996) Small molecule combinatorial libraries via Parke-Davis' DIVERSOMER method. Chem. Brit., #2420

53. Dankwardt, S.M., Phan, T.M., & Krstenansky, J.L. (1996) Combinatorial synthesis of small-molecule libraries using 3- amino-5-hydroxybenzoic acid. Mol. Diversity, 1, 113-120. #2825 (Available on Internet)

54. de Bont, D.B.A., Moree, W.J., & Liskamp, R.M.J. (1996) Molecular diversity of peptidomimetics: Approaches to the solid- phase synthesis of peptidosulfonamides. Bioorg. Med. Chem., 4, 667-672. #4623

55. de Bont, D.B.A., Dijkstra, G.D.H., den Hartog, J.A.J., & Liskamp, R.M.J. (1996) Solid-phase synthesis of peptidosulfonamide containing peptides derived from Leu-enkephalin. Bioorg. Med. Chem. Lett., 6, 3035-3040. #8259

56. Devraj, R., & Cushman, M. (1996) A versatile solid phase synthesis of lavendustin A and certain biologically active analogs. J. Org. Chem., 61, 9368-9373. #8250

57. DiCesare, J.C., McComas, C.B., Thomas, J. & Carroll, F.I. (1996) Modification of the titanium isopropoxide catalyzed reductive amination reaction and its application to solid phase synthesis. In Anonymous, Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28. (pp. ORGN-91. American Chemical Society,Washington,D, #6296

58. Ding, Y., Labbe, J., Kanie, O., & Hindsgaul, O. (1996) Towards oligosaccharide libraries: A study of the random galactosylation of unprotected N-acetylglucosamine. Bioorg. Med. Chem., 4, 683-692. #4626

59. Dinh, T.Q., & Armstrong, R.W. (1996) Synthesis of ketones and aldehydes via reactions of Weinreb-type amides on solid support. Tetrahedron Lett., 37, 1161-1164. #3883

60. Dorner, B., Husar, G.M., Ostresh, J.M., & Houghten, R.A. (1996) The synthesis of peptidomimetic combinatorial libraries through succesive amide alkylations. Bioorg. Med. Chem., 4, 709-715. #4629

61. Dressman, B.A., Spangle, L.A., & Kaldor, S.W. (1996) Solid phase synthesis of hydantoins using a carbamate linker and a novel cyclization/cleavage step. Tetrahedron Lett., 37, 937-940. #3885

62. Dygutsch, D.P., & Eilbracht, P. (1996) Synthesis of cyclopentanone derivatives with polystyrene-supported cyclopentadienyl rhodium catalysts. Tetrahedron, 52, 5461-5468. #5632

63. Eggenweiler, H.M. & Bayer, E. (1996) Gel-phase (13)C-NMR monitoring of solid phase glycoside synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 363-366). Mayflower Scientific Limited, Birmingham. #8952

64. Egner, B.J., Cardno, M., & Bradley, M. (1996) Linkers for combinatorial chemistry and reaction analysis using solid phase in situ mass spectrometry. J. Chem. Soc. Chem. Commun., 2163-2164. #4130

65. Ellman, J. A. The solid phase synthesis of complex small molecules. . 1996. Lecture at the conference "Synthesis of Small Molecules on Solid Phase",Basel,1996. #8488

66. Elofsson, M., Roy, S., Salvador, L.A., & Kihlberg, J. (1996) Building blocks for glycopeptide synthesis: Preparation of alpha-O-fucosylated Fmoc serine and threonine in one step from L-fucose tetraacetate. Tetrahedron Lett., 37, 7645-7648. #6347 4479

67. Emery, F., Bisang, C., Favre, M., Jiang, L., & Robinson, J.A. (1996) A template for the solid-phase synthesis of conformationally restricted protein loop mimetics. Chem. Commun., 2155-2156. #5696

68. Felder, E.R., Heizmann, G., Matthews, I.T., Rink, H., & Spieser, E. (1996) A new combination of protecting groups and links for encoded synthetic libraries suited for consecutive tests on the solid phase and in solution. Mol. Diversity, 1, 109-112. #4119 (Available on Internet)

69. Fell, J.B., Chin, J.A., Shapiro, M.J. & Wareing, J.R. (1996) Analytical techniques in combinatorial chemistry: HPLC NMR of a mixture of positional isomers. In Anonymous, Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28. (pp. ANYL-29. American Chemical Society,Washington,D, #6383

70. Filippov, D., Meeuwenoord, N.J., van der Marel, G.A., Efimov, V.P., Kuyl-Yeheskiely, E., & van Boom, J.H. (1996) An approach to the solid phase synthesis of oligonucleotides containing N-acylphosphoramidate internucleosidic linkages. Synlett, 769-771. #5255

71. Fitzgerald, M.C., Harris, K., Shevlin, C.G., & Siuzdak, G. (1996) Direct characterization of solid phase resin-bound molecules by mass spectrometry. Bioorg. Med. Chem. Lett., 6, 979-982. #5755

72. Flegelova, Z., & Patek, M. (1996) Bis-allylic templates for Pd(O)-catalyzed solid phase synthesis of tertiary amines. J. Org. Chem., 61, 6735-6738. #5394

73. Floyd, C.D., Lewis, C.N., Patel, S.R., & Whittaker, M. (1996) A method for the synthesis of hydroxamic acids on solid phase. Tetrahedron Lett., 37, 8045-8048. #5756

74. Fruchtel, J.S. & Jung, G. (1996) Polymer supported organic synthesis: A review. In G. Jung (Ed.), Combinatorial Peptide and Nonpeptide Libraries: A Handbook. (pp. 19-78). VCH, Weinheim. #9664

75. Fruchtel, J.S., & Jung, G. (1996) Organic chemistry on solid supports. Angew. Chem. Int. Ed., 35, 17-42. #3975

76. Furka, A., Campian, E., Peterson, M., Saneii, H.H. & Chou, J. (1996) Combinatorial chemistry: Past and present developments. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 151-158). Mayflower Scientific Limited, Birmingham. #8916

77. Garigipati, R.S., Adams, B., Adams, J.L., & Sarkar, S.K. (1996) Use of spin echo magic angle spinning H-1 NMR in reaction monitoring in combinatorial organic synthesis. J. Org. Chem., 61, 2911-2914. #4570

78. Gayo, L.M., & Suto, M.J. (1996) Use of pentafluorophenyl esters for one-pot protectional/activation of amino and thiol carboxylic acids. Tetrahedron Lett., 37, 4915-4918. #5761

79. Gerster, M., Bleicher, K. & Bayer, E. (1996) Comparison of several sulfurizing reagents for synthesis of phosphorothioate oligonucleotides on different supports. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 377-380). Mayflower Scientific Limited, Birmingham. #8955

80. Goff, D.A., & Zuckermann, R.N. (1996) The synthesis of 2-oxopiperazines by intramolecular Michael addition on solid support. Tetrahedron Lett., 37, 6247-6250. #5252

81. Gong, B., Chen, X., Cheng, M., Li, R., Kenyon, G.L. & Cohen, F.E. (1996) Structure-based design and solid phase synthesis of cysteine protease inhibitors for parasitic diseases. In Anonymous, Book of Abstracts, 212th ACS National Meeting, Orlando, FL, August 25-29. (pp. MEDI-39. American Chemical Society,Washington,D, #6534 4335

82. Goodfellow, V.S., Laudeman, C.P., Gerrity, J.I., Burkhard, M., Strobel, E. & McLeod, D.A. (1996) Rationally designed diverse non-peptides: Variously substituted piperazine and piperazinedione libraries targeted for the discovery of bradykinin and other G-protein coupled receptor antagonists. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 381-384). Mayflower Scientific Limited, Birmingham. #3242

83. Gooding, O., Hoeprich, P.D.Jr., Labadie, J.W., Porco, J.A.Jr., van Eikeren, P. & Wright, P. (1996) Boosting the productivity of medicinal chemistry through automation tools: Novel technological developments enable a wide range of automated synthetic procedures. In I.M. Chaiken & K.D. Janda (Eds.), Molecular Diversity and Combinatorial Chemistry. Libraries and Drug Discovery. (pp. 199-206). American Chemical Society, Washington,DC. #5112

84. Gordeev, M.F., Patel, D.V., Wu, J., & Gordon, E.M. (1996) Approaches to combinatorial synthesis of heterocycles: Solid phase synthesis of pyridines and pyrido[2,3-d]pyrimidines. Tetrahedron Lett., 37, 4643-4646. #4856

85. Gordeev, M.F., Patel, D.V., & Gordon, E.M. (1996) Approaches to combinatorial synthesis of heterocycles: A solid- phase synthesis of 1,4-dihydropyridines. J. Org. Chem., 61, 924-928. #3758

86. Gordon, E.M., Gallop, M.A., & Patel, D.V. (1996) Strategy and tactics in combinatorial organic synthesis. Applications to drug discovery. Account. Chem. Res., 29, 144-154. #3593

87. Gosselin, F., Direnzo, M., Ellis, T.H., & Lubell, W.D. (1996) Photoacoustic FTIR spectroscopy, a nondestructive method for sensitive analysis of solid-phase organic chemistry. J. Org. Chem., 61, 7980-7981. #5767

88. Gouilleux, L., Fehrentz, J.A., Winternitz, F., & Martinez, J. (1996) Solid phase synthesis of chiral 3-substituted quinazoline-2,4-diones. Tetrahedron Lett., 37, 7031-7034. #5466

89. Gremlich, H.U., & Berets, S.L. (1996) Use of FT-IR internal reflection spectroscopy in combinatorial chemistry. Appl. Spectrosc., 50, 532-536. #4590

90. Griffith, M.C., Dooley, C.T., Houghten, R.A. & Kiely, J.S. (1996) Solid-phase synthesis, characterization, and screening of a 43, 000-compound tetrahydroisoquinoline combinatorial library. In I.M. Chaiken & K.D. Janda (Eds.), Molecular Diversity and Combinatorial Chemistry. Libraries and Drug Discovery. (pp. 50-57). American Chemical Society, Washington,DC. #5098

91. Gude, M., Piarulli, U., Potenza, D., Salom, B., & Gennari, C. (1996) A new method for the solution and solid phase synthesis of chiral b -sulfonopeptides under mild conditions. Tetrahedron Lett., 37, 8589-8592. #5736

92. Guiles, J.W., Johnson, S.G. & Murray, W.V. (1996) Solid phase Suzuki for C-C bond formation. In Anonymous, Book of Abstracts, 211th ACS National Meeting, New Orleans, LA, March 24-28. (pp. ORGN-126. American Chemical Society,Washington,D, #6569

93. Guiles, J.W., Johnson, S.G., & Murray, W.V. (1996) Solid-phase Suzuki coupling for C-C bond formation. J. Org. Chem., 61, 5169-5171. #5143

94. Hamper, B.C., Dukesherer, D.R., & South, M.S. (1996) Solid-phase synthesis of proline analogs via a three component 1, 3-dipolar cycloaddition. Tetrahedron Lett., 37, 3671-3674. #4935

95. Han, Y., Walker, S.D., & Young, R.N. (1996) Silicon directed ipso-subtitution of polymer bound arylsilanes: Preparation of biaryls via the Suzuki cross-coupling reaction. Tetrahedron Lett., 37, 2703-2706. #4742

96. Hanessian, S., & Yang, R.Y. (1996) Solution and solid phase synthesis of 5-alkoxyhydantoin libraries with a three-fold functional diversity. Tetrahedron Lett., 37, 5835-5838. #5232

97. Hanessian, S., & Devasthale, P.V. (1996) Generation of functional diversity via nitroaldol condensations of a-aminoacid aldehydes. A new and stereocontrolled route to acyclic 1,3-diamino-2-alcohols. Tetrahedron Lett., 37, 987-990. #3886

98. Harness, J., Baker, W., and Towell, J. A workstation for performing all aspects of organic synthesis. In: Anonymous. (Eds.) American Chemical Society, Orlando p.MEDI 007 212th ACS National Meeting. #11422OLD

99. Harness, J.R. (1996) Automation of high-throughput synthesis: Automated laboratory workstations designed to perform and support combinatorial chemistry. In I.M. Chaiken & K.D. Janda (Eds.), Molecular Diversity and Combinatorial Chemistry. Libraries and Drug Discovery. (pp. 188-198). American Chemical Society, Washington,DC. #5107

100. Hartsel, S.A., & Marshall, W.S. (1996) Solid-phase synthesis of carbohydrate and phosphodiester modified 2'- 5' oligoadenylate analogs. Bioorg. Med. Chem. Lett., 6, 2993-2998. #8258

101. Hebert, N. (1996) Convergent solid-phase synthesis of phosphoramidate combinatorial libraries. In I.M. Chaiken & K.D. Janda (Eds.), Molecular Diversity and Combinatorial Chemistry. Libraries and Drug Discovery. (pp. 40-49). American Chemical Society, Washington,DC. #3651

102. Henkel, B. & Bayer, E. (1996) p-(5-Dibenzosuberenyl-5-hydroxy)-benzoic acid: A new linker for peptide synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 395-398). Mayflower Scientific Limited, Birmingham. #8957

103. Hermkens, P.H.H., Ottenheijm, H.C.J., & Rees, D. (1996) Solid-phase organic reactions: A review of the recent literarure. Tetrahedron, 52, 4527-4554. #4298

104. Hoeg-Jensen, T., Spatola, A.F., & Holm, A. (1996) Amino monothio acids in solid-phase synthesis of peptide thioamides. Int. J. Peptide Prot. Res., 47, 190-200. #4755

105. Hoekstra, W.J., Maryanoff, B.E., Andrade-Gordon, P., Cohen, J.H., Costanzo, M.J., Damiano, B.P., Haertlein, B.J., Harris, B.D., Kauffman, J.A., Keane, P.M., McComsey, D.F., Villani, F.J., & Yabut, S.C. (1996) Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ- 50042. Bioorg. Med. Chem. Lett., 6, 2371-2376. #6665

106. Hoeprich, P.D.Jr. (1996) Automated solid phase synthesis of small organic molecules. Nat. Biotech., 14, 1311-1313. #6667

107. Hogan, J.C.Jr. (1996) Directed combinatorial chemistry. Nature, 384, 17-19. #5772

108. Hollinshead, S.P. (1996) Synthesis and reactions of heterocyclic libraries on a solid support. In Anonymous, Book of Abstracts, 212th ACS National Meeting, Orlando, FL, August 25-29. (pp. ORGN-156. American Chemical Society,Washington,D, #6671

109. Hollinshead, S.P. (1996) Stereoselective synthesis of highly functionalized pyrrolidines via 1,3-dipolar cycloaddition reactions on a solid support. Tetrahedron Lett., 37, 9157-9160. #8167

110. Hughes, I. (1996) Application of polymer-bound phosphonium salts as traceless supports for solid phase synthesis. Tetrahedron Lett., 37, 7495-7498. #5540

111. Hunt, J.A., & Roush, W.R. (1996) Solid-phase synthesis of 6-deoxyoligosaccharides. J. Amer. Chem. Soc., 118, 9998-9999. #5551

112. Hutchins, S.M., & Chapman, K.T. (1996) Fischer indole synthesis on a solid support. Tetrahedron Lett., 37, 4869-4872. #4901

113. Hutchins, S.M., & Chapman, K.T. (1996) Solid phase synthesis of tetrahydroisoquinolines & tetrahydroimidazopyridines. Tetrahedron Lett., 37, 4865-4868. #4900

114. Ito, Y., Kanie, O., & Ogawa, T. (1996) Orthogonal glycosylation strategy for rapid assembly of oligosaccharides on a polymer support. Angew. Chem. Int. Ed., 35, 2510-2512. #8667

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