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List of articles in robotics and automation

This list is arranged by the year and the name of the first author. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (michal@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M., Leblova Z.: Dynamic database of references in molecular diversity. Internet http://www.5z.com.


Recently added entries are marked in bold

  1. Aria,F. (2001) Automated multistep solution phase synthesis of diamines and allylic amines. In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 223-227). Marcel Dekker, Inc., New York. #16467

  2. Barkley,A., & Arya,P. (2001) Combinatorial chemistry toward understanding the function(s) of carbohydrates and carbohydrate conjugates. Chem. Eur. J., 7, 555-563. #16247

  3. Baru,M.B., Mustaeva,L.G., Vagenina,I.V., Gorbunova,E.Y., & Cherskii,V.V. (2001) Pressure monitoring of continuous-flow solid-phase peptide synthesis. J. Pept. Res., 57, 193-202. #16617

  4. Bickler,J.R., & Rahn,P.C. (2001) High-throughput parallel flash purification using an automated, multichannel UV flash chromatography system. Amer. Lab., 33, 46. #16754

  5. Chaturvedi,S., Fisher,P.V., Otteson,K.M. & Bergot,B.J. (2001) Automated robotic parallel synthesis of a small-molecule library using multistep reactions on solid support. In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 169-186). Marcel Dekker, Inc., New York. #16462

  6. Deo,S.K., & Daunert,S. (2001) Luminescent proteins from Aequorea victoria: Applications in drug discovery and in high throughput analysis. Fresenius J. Anal. Chem., 369, 258-266. #16791

  7. Edwards,B.S., Kuckuck,F.W., Prossnitz,E.R., Ransom,J.T., & Sklar,L.A. (2001) HTPS flow cytometry: A novel platform for automated high throughput drug discovery and characterization. J. Biomol. Screen., 6, 83-90. #16798

  8. Felten,C., Foret,F., Minarik,M., Goetzinger,W., & Karger,B.L. (2001) Automated high-throughput infusion ESI-MS with direct coupling to a microtiter plate. Anal. Chem., 73, 1449-1454. #16805

  9. Fu,W., Wang,J., Liu,M., & Wang,Y. (2001) P.R.o.C.Medical Laboratory Center of South Western Hospital Third Military Medical University. Apparatus and method for combinatorial and automatic detection of a target gene. WO PCT. 01/36667. 1999-192/CN-A1, 1 p. #16658

  10. Haag,R. (2001) Dendrimers and hyperbranched polymers as high-loading supports for organic synthesis. Chem. Eur. J., 7, 327-335. #16296

  11. Hoeprich,P.D.Jr. (2001) Automating high-throughput organic synthesis. In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 157-167). Marcel Dekker, Inc., New York. #16461

  12. Hu,Y., Baudart,S. & Porco,J.A.Jr. (2001) Multistep synthesis of 1,2,3-thiadiazoles using "Catch and release". In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 215-222). Marcel Dekker, Inc., New York. #16466

  13. Kirchhoff,E., & Cassidy,C.S. (2001) Industrial applications of automated process research. Chim. Oggi, 19, 69-71. #16689

  14. Lebl,M., Pires,J., Burger,C., Ni,Y. & Chen,Y. (2001) Solid-phase parallel synthesis of large tetrahydroisoquinolinone library. In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 187-195). Marcel Dekker, Inc., New York. #16463

  15. Lebl,M. & Pires,J. (2001) Solid-phase parallel synthesis of a large array of tetrahydroisoquinolinones. In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 197-205). Marcel Dekker, Inc., New York. #16464

  16. Li,R., Xiao,X.Y. & Nicolaou,K.C. (2001) High-output solid-phase synthesis of discrete coumpounds using directed split-and-pool strategy. In I.Sucholeiki (Ed.), High-Throughput Synthesis. (pp. 207-213). Marcel Dekker, Inc., New York. #16465

  17. Plante,O.J., Palmacci,E.R., & Seeberger,P.H. (2001) Automated solid-phase synthesis of oligosaccharides. Science, 291, 1523-1527. #16929

  18. Ro,S., Lee,H.J., Ahn,I.A., Shin,D.K., Lee,K.B., Yoon,C.J., & Choi,Y.S. (2001) Torsion angle based design of peptidomimetics: A dipeptidic template adopting beta-I turn (Ac-Aib-AzGly-NH2). Bioorg. Med. Chem., 9, 1837-1841. #16943

  19. Van den Nest,W., Yuval,S., & Albericio,F. (2001) Cu(OBt)(2) and Cu(OAt)(2), copper(II)-based racemization suppressors ready for use in fully automated solid-phase peptide synthesis. J. Peptide Sci., 7, 115-120. #16996

  20. Walter,G., Konthur,Z., & Lehrach,H. (2001) High-throughput screening of surface displayed gene products. Comb. Chem. High Throughput Screening, 193-205. #16697

  21. Carey,R.I. (2000) I.A.G.U.University of Georgia Research Foundation. Na-a,a-dimethyl-3,5-dialkoxylbenzylcarbonyl amino acid 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazin-3-yl and pentafluorophenylesters. US Patent. 6,075,141. 891,134, #14904

  22. Castelino,P., Lewis,D., Shimmin,D., Clough,G., & Harding,D. (2000) Automated sample storage for drug discovery. Chim. Oggi, 17, 32-35. #13891

  23. Curran,D.P., Hadida,S., Studer,A., He,M., Kim,S.Y., Luo,Z., Larhed,M., Hallberg,A. & Linclau,B. (2000) Experimental techniques in fluorous synthesis: A user's guide. In H.Fenniri (Ed.), Combinatorial Chemistry: A Practical Approach. (pp. 327-352). Oxford University Press, Oxford. #15673

  24. Davis,P.W., & Swayze,E.E. (2000) Automated solid-phase synthesis of linear nitrogen-linked compounds. Biotechnol. Bioeng., 71, 19-27. #13944

  25. Dukler,A., & Dotan,N. (2000) Carbozyme Nt.Ltd. Combinatorial complex carbohydrate libraries and methods for automated synthesis and uses thereof. WO PCT. 00/49412. 2000-99/IL-A1, 1 p. #15574

  26. Enjalbal,C., Martinez,J., & Aubagnac,J.L. (2000) Mass spectrometry in combinatorial chemistry. Mass Spectrom. Rev., 19, 139-161. #15022

  27. Flavin,M.T., & Seaney,L.M. (2000) I.L.I.U.Advanced Life Sciences. Use of automated technology in chemical process research and development. US Patent. 6,044,212. 862,840, #14787

  28. Furka,A., Hamaker,L.K. & Peterson,M.L. (2000) Synthesis of combinatorial libraries using the portioning-mixing procedure. In H.Fenniri (Ed.), Combinatorial Chemistry: A Practical Approach. (pp. 1-32). Oxford University Press, Oxford. #15664

  29. Gildea,B.D., & Coull,J.M. (2000) I.F.M.U.PerSeptive Biosystems. Methods for automated synthesis of PNA-DNA chimeras and compositions thereof. US Patent. 6,063,569. 910,552, #14471

  30. Groger,H., Sans,J., & Guthner,T. (2000) 1,3,5-Triazines, versatile industrial building blocks: Synthetic approaches and applications. Chim. Oggi, 18, 12-16. #14397

  31. Haag,B.T. (2000) Chemspeed Ltd.: Automated and unattended parallel synthesis integrating work-up and analysis. Chimia, 54, 163-164. #15067

  32. Hiebl,J., Hsu,L., Ping,L.J., Shetzline,S.B., Webb,E.C., Armitage,M., Smith,G., & Veal,K. (2000) Automated catalyst screening: An important tool to speed-up the chemical process development in the pharmaceutical industry. Chim. Oggi, 18, 41-44. #16431

  33. Hu,X., Smith,G.D., Sykora,M., Lee,S.J., & Grinstaff,M.W. (2000) Automated solid-phase synthesis and photophysical properties of oligodeoxynucleotides labeled at 5'-aminothymidine with Ru(bpy)(2)(4-m-4'-cam-bpy)(2+). Inorg. Chem., 39, 2500-2504. #15098

  34. Hulme,C., Ma,L., Cherrier,M.P., Romano,J.J., Morton,G., Duquenne,C., Salvino,J., & Labaudiniere,R. (2000) Novel applications of convertible isonitriles for the synthesis of mono and bicyclic g-lactams via a UDC strategy. Tetrahedron Lett., 41, 1883-1887. #14345

  35. Kedar,H., Sugarman,J.H., Binnie,A.A., Barrett,R.W., Chan,S., & Martin,E.L. (2000) I.R.T.P.N.U.Glaxo Wellcome. Method and apparatus for transferring and combining reagents. US Patent. 6,083,761. 982,068, #14778

  36. Kedar,H., Sugarman,J.H., Binnie,A.A., & Barrett,R.W. (2000) I.R.T.P.N.U.Glaxo Wellcome. Method and apparatus for transferring and combining distinct chemical compositions with reagents. US Patent. 6,054,325. 887,141, #14475

  37. Keifer,P.A., Smallcombe,S.H., Williams,E.H., Salomon,K.E., Mendez,G., Belletire,J.L., & Moore,C.D. (2000) Direct-injection NMR (DI-NMR): A flow NMR technique for the analysis of combinatorial chemistry libraries. Journal of Combinatorial Chemistry, 2, 151-171. #14380

  38. Lake,D.A., Johnson,M.V., McEwen,C.N., & Larsen,B.S. (2000) Sample preparation for high throughput accurate mass analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom., 14, 1008-1013. #15154

  39. Lebl,M., Pokorny,V., & Krchnak,V. (2000) I.S.D.C.U.Trega Biosciences. Apparatus and method for combinatorial chemistry synthesis. US Patent. 6,045,755. 815,975, #14465

  40. Lebl,M. (2000) New technique for high-throughput synthesis of peptides, peptidomimetics and nonpeptide small organic molecule arrrays. In G.B.Fields, J.P.Tam & G.Barany (Eds.), Peptides for the New Millennium. (pp. 164-166). Kluwer Academic Publisher, Dordrecht. #15715

  41. Lee,Y.S., Lee,H.J., Lee,D. & Kim,H.J. (2000) Nsc- and Fmoc-amino acids for automated solid-phase peptide synthesis: Comparative study of the stability in various conditions. In G.B.Fields, J.P.Tam & G.Barany (Eds.), Peptides for the New Millennium. (pp. 53-54). Kluwer Academic Publisher, Dordrecht. #15693

  42. Lewis,K., Phillips,D., & Sefler,A. (2000) Automated high-throughput quantification of combinatorial arrays. American Pharmaceutical Review, 3, 63-68. #15428

  43. Licha,K., Bhargava,S., Rheinlander,C., Becker,A., Schneider-Mergener,J., & Volkmer-Engert,R. (2000) Highly parallel nano-synthesis of cleavable peptide-dye conjugates on cellulose membranes. Tetrahedron Lett., 41, 1711-1715. #14337

  44. Manly,C.J. (2000) Managing laboratory automation: Integration and informatics in drug discovery. Journal of Automated Methods and Management in Chemistry, 22, 169-170. #16337

  45. North,N. (2000) Implementation of analytical technologies in a pharmaceutical development organization-looking into the next millennium. Journal of Automated Methods and Management in Chemistry, 22, 41-45. #15224

  46. Papen,R.F., Pelc,R.E., Chibucos,N.S., & Meyer,W. (2000) D.G.I.U.Packard Instruments Company. Microvolume liquid handling system. US Patent. 6,083,762. 008,019, #14777

  47. Papen,R.F., Pelc,R.E., Chibucos,N.S., & Meyer,W. (2000) D.G.I.U.Packard Instruments Company. Method for aspirating sample liquid into a dispenser tip and thereafter ejecting droplets therethrough. US Patent. 6,079,283. 012,174, #14779

  48. Peng,S.X., Henson,C., Strojnowski,M.J., Golebiowski,A., & Klopfenstein,S.R. (2000) Automated high-throughput liquid-liquid extraction for initial purification of combinatorial libraries. Anal. Chem., 72, 261-266. #14104

  49. Romanelli,A., De Napoli,L., Messere,A., Montesarchio,D., Piccialli,G., Zaccaro,L., Pedone,C., Rossi,F. & Benedetti,E. (2000) Fully automated synthesis of peptide-oligonucleotide conjugates. In G.B.Fields, J.P.Tam & G.Barany (Eds.), Peptides for the New Millennium. (pp. 784-785). Kluwer Academic Publisher, Dordrecht. #15752

  50. Rust,W.C., & Nielson,R.B. (2000) I.S.C.C.U.Symyx Technologies. Synthesizing combinatorial libraries of materials. WO PCT. 00/67086. 2000-12228/US-A1, 1 p. #15809

  51. Sojka,B., Piunno,P.A.E., Wust,C.C., & Krull,U.J. (2000) A novel phosphoramidite method for automated synthesis of oligonucleotides on glass supports for biosensor development. Appl. Biochem. Biotech., 89, 85-103. #16073

  52. Studt,T. (2000) Raising the bar on combinatorial discovery. Drug. Dis. Develop., 24-29. #13892

  53. Sugawara,T. & Cork,D.G. (2000) Automated solution phase synthesis and its application in combinatorial chemistry. In H.Fenniri (Ed.), Combinatorial Chemistry: A Practical Approach. (pp. 373-400). Oxford University Press, Oxford. #15675

  54. Tommasi,R.A., Whaley,L.W., & Marepalli,H.R. (2000) AutoChem: Automated solution-phase parallel synthesis and purification via HPLC. Journal of Combinatorial Chemistry, 2, 447-449. #15595

  55. Udaka,K., Wiesmuller,K.H., Kienle,S., Jung,G., Tamamura,H., Yamagishi,H., Okumura,K., Walden,P., Suto,T., & Kawasaki,T. (2000) An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries. Immunogenetics, 51, 816-828. #15784

  56. van Well,R.M., Overkleeft,H.S., Overhand,M., Carstenen,E.V., van der Marel,G.A., & van Boom,J.H. (2000) Parallel synthesis of cyclic sugar amino acid/amino acid hybrid molecules. Tetrahedron Lett., 41, 9331-9335. #16104

  57. Verheijen,J.C., van der Marel,G.A., van Boom,J.H., & Metzler-Nolte,N. (2000) Transition metal derivatives of peptide nucleic acid (PNA) oligomers-synthesis, characterization, and DNA finding. Bioconjug. Chem., 11, 741-743. #16403

  58. Verheijen,J.C., Chen,L., Bayly,S.F., Torrence,P.F., van der Marel,G.A., & van Boom,J.H. (2000) Synthesis and RNase L binding and activation of a 2-5A-(5')-DNA-(3')-PNA chimera, a novel potential antisense molecule. Nucleosides, Nucleotides and Nucleic Acids, 19, 1821-1830. #16402

  59. Whalen,K.M., Rogers,K.J., Cole,M.J., & Janiszewski,J.S. (2000) AutoScan: An automated workstation for rapid determination of mass and tandem mass spectrometry conditions for quantitative bioanalytical mass spectrometry. Rapid Commun. Mass Spectrom., 14, 2074-2079. #16115

  60. Zechel,C. (2000) Automation and devices for combinatorial chemistry and parallel organic synthesis. In R.Mannhold, H.Kubinyi & H.Timmerman (Eds.), Combinatorial Chemistry: A Practical Approach. (pp. 243-276). Wiley-VCH, Weinheim. #16218

  61. Ahn,I.A., Kim,S.W., & Ro,S. (1999) Solid phase synthesis of azapeptides using an automatic synthesizer. Mol. Diversity, 4, 23-24. #12922

  62. Albericio,F., & Kates,S.A. (1999) I.F.M.U.PerSeptive Biosystems. Automated allyl deprotection in solid-phase synthesis. US Patent. 5,861,351. 717,208, #13170

  63. Altreuter,D.H., & Clark,D.S. (1999) Combinatorial biocatalysis: Taking the lead from Nature. Curr. Opin. Biotechnol., 10, 130-136. #12706

  64. Andrus,A., Cox,S., Beavers,S., Parker,A., Anuskiewicz,J. & Mullah,B. (1999) High-throughput synthesis of functionalized oligonucleotides. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 67-70). Mayflower Scientific Limited, Birmingham. #13462

  65. Andrus,W.A., McCollum,C.D., & Zon,G. (1999) F.C.C.U.The Perkin-Elmer Corporation. Automated system for polynucleotide synthesis and purification. US Patent. 5,935,527. 055,464, #14518

  66. Angell,Y.M., Jensen,K.J., Gross,C.M. & Barany,G. (1999) Solid-phase synthesis of peptide nucleic analogue (PNA) sequences taken to new lengths. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 59-62). Mayflower Scientific Limited, Birmingham. #13460

  67. Antonenko,V.V. (1999) Automation in combinatorial chemistry. In Anonymous, Combinatorial Chemistry and Technology: Principles, Methods, and Applications. (pp. 205-232). #13471

  68. Archer,R. (1999) Industrializing drug discovery. Amer. Lab., 31, 17-23. #13756

  69. Bagno,A., Bicciato,S., Di Bello,C. & Bonora,G.M. (1999) Automated liquid-phase biopolymer synthesis. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 51-54). Mayflower Scientific Limited, Birmingham. #13458

  70. Boguslavsky,J. (1999) Need protein? Organic chemistry holds the key. Drug. Dis. Develop., 30-33. #12914

  71. Brenner,S. (1999) I.H.C.U.Lynx Therapeutics. Method of sorting polynucleotides. US Patent. 5,863,722. 485,105, #13255

  72. Brooking,P., Doran,A., Grimsey,P., Hird,N.W., MacLachlan,W.S., & Vimal,M. (1999) Split-split. A multiple synthesiser approach to efficient automated parallel synthesis. Tetrahedron Lett., 40, 1405-1408. #12319

  73. Brown,A., Akinsanya,A.A., Barker,S.J., Brophy,M., Dobb,A.K., Doyle,S.M., Hudson,I.R., Minter,S.J., Wraith,M.J., & Oultram,J.D. (1999) Automated system for capture and detection of nucleic acids. BioTechniques, 27, 176-180. #13105

  74. Caciagli,V., Cardinali,F., Sisto,A. & Lombardi,P. (1999) Scaling-up procedure for continuous flow SPPS. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 63-66). Mayflower Scientific Limited, Birmingham. #13461

  75. Calvert,S., Stewart,F.P., Swarna,K., & Wiseman,J.S. (1999) The use of informatics and automation to remove bottlenecks in drug discovery. Curr. Opin. Drug. Disc. Develop., 2, 234-238. #13397

  76. Casale,R.A., Paul,C.H., Jensen,I.S., Moyer,M.L., Kates,S.A. & Egholm,M. (1999) A comparison of solid supports for PNA synthesis. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 139-142). Mayflower Scientific Limited, Birmingham. #13665

  77. Doi,T., Hijikuro,I., & Takahashi,T. (1999) A novel strategy for the automated synthesis of bis-amides of 1,2-diamines. Synlett, 1751-1753. #15012

  78. Drolet,D.W., Jenison,R.D., Smith,D.E., Pratt,D., & Hicke,B.J. (1999) A high throughput platform for systematic evolution of ligands by exponential enrichment (SELEX (TM)). Comb. Chem. High Throughput Screening, 2, 271-278. #13954

  79. Du,H., Jindal,S., & Lindsey,J.S. (1999) Implementation of the multidirectional search algorithm on an automated chemistry workstation. A parallel yet adaptive approach for reaction optimization. Chemometr. Intell. Lab. Syst., 48, 235-256. #13375

  80. Du,H., Shen,W., Kuo,P.Y., & Lindsey,J.S. (1999) Decision-tree programs for an adaptive automated chemistry workstation. Application to catalyst screening experiments. Chemometr. Intell. Lab. Syst., 48, 205-217. #13374

  81. Du,H., Corkan,A., Yang,K., Kuo,P.Y., & Lindsey,J.S. (1999) An automated microscale chemistry workstation capable of parallel, adaptive experimentation. Chemometr. Intell. Lab. Syst., 48, 181-203. #13373

  82. Ecker,D.J., Acevedo,O., Hebert,N., Davis,P.W., Wyatt,J.R., & Kiely,J.S. (1999) C.C.U.ISIS Pharmaceuticals Inc. Chemical reaction apparatus for performing multiple reaction on a surface and collecting the product. US Patent. 5,925,732. 778,876, #13136

  83. Epton,R. (1999) Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. Mayflower Scientific Limited, Birmingham. ISBN 0952701138 #13448

  84. Felder,R. (1999) A new automation tool for medicinal and combinatorial chemists. JALA, 4, 46-47. #14352

  85. Freemantle,M. (1999) Downsizing chemistry. Chemical analysis and synthesis on microchips promise a variety of potential benefits. C&EN, 77, 27-36. #12619

  86. Ganguly,D., & Rodriguez,M.J. (1999) Cyclopeptamine lipopeptide antifungal agents. Exp. Opin. Ther. Patents, 9, 67-71. #12358

  87. Gast,R., Glokler,J., Hoxter,M., Kiess,M., Frank,R., & Tegge,W. (1999) Method for determining protein kinase substrate specificities by the phosphorylation of peptide libraries on beads, phosphate-specific staining, automated sorting, and sequencing. Anal. Biochem., 276, 227-241. #13976

  88. Goodman,B.A. (1999) Managing the workflow of a high-throughput organic synthesis laboratory: A marriage of automation and information management technologies. JALA, 4, 48-52. #14353

  89. Gorlach,E., & Richmond,R. (1999) Discovery of quasi-molecular ions in electrospray spectra by automated searching for simultaneous adduct mass differences. Anal. Chem., 71, 5557-5562. #13989

  90. Greig,M. (1999) Use of automated HPLC-MS analysis for monitoring and improving the purity of combinatorial libraries. Amer. Lab., 31, 28. #15062

  91. Harness,J.R. (1999) Automated sample preparation to support high throughput new compound discovery. Chim. Oggi, 17, 22-24. #12910

  92. Henke,L., & Krull,U.J. (1999) Immobilization technologies used for nucleic acid biosensors: A review. Canadian Journal of Analytical Sciences and Spectroscopy, 44, 61-70. #15081

  93. Hird,N.W. (1999) Automated synthesis: New tools for the organic chemist. Drug Disc. Today, 4, 265-274. #14014

  94. Karet,G. (1999) Bead-picking made simple. Drug. Dis. Develop., 55. #12918

  95. Karet,G. (1999) Microplate readers kleep pace with miniaturization. Drug. Dis. Develop., 44-48. #12917

  96. Khan,S.I., & Grinstaff,M.W. (1999) Palladium(0)-catalyzed modification of oligonucleotides during automated solid-phase synthesis. J. Amer. Chem. Soc., 121, 4704-4705. #12875

  97. Khan,S.I., Beilstein,A.E., & Grinstaff,M.W. (1999) Automated solid-phase synthesis of site-specifically labeled ruthenium-oligonucleotides. Inorg. Chem., 38, 418. #12763

  98. Kiselyov,A.S., & Dominguez,C. (1999) A novel synthesis of 3,4-disubstituted cinnolines from o-trifluorophenyl hydrazones. Tetrahedron Lett., 40, 5111-5114. #13116

  99. Krchnak,V. (1999) Semi-automated high throughput combinatorial solid-phase organic synthesis. Biotech. Bioeng. (Comb. Chem. ), 61, 135-141. #13368

  100. Kuisle,O., Quinoa,E., & Riguera,R. (1999) A general methodology for automated solid-phase synthesis of depsides and depsipeptides. Preparation of a valinomycin analogue. J. Org. Chem., 64, 8063-8075. #14045

  101. Kuo,P.Y., Du,H., Corkan,A., Yang,K., & Lindsey,J.S. (1999) A planning module for performing grid search, factorial design, and related combinatorial studies on an automated chemistry workstation. Chemometr. Intell. Lab. Syst., 48, 219-234. #13376

  102. Kusumoto,S., & Fukase,K. (1999) L.O.J.Wako Pure Chemical Industries. Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups. US Patent. 5,998,595. 961,174, #14502

  103. Lebl,M. & Krchnak,V. (1999) Techniques for massively parallel synthesis of small organic molecules. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 43-46). Mayflower Scientific Limited, Birmingham. #10056

  104. Maiefski,R.R., & Wendell,D. (1999) C.C.U.Ontogen Corporation. Sample wash station assembly. US Patent. 5,976,470. 087,376, #14859

  105. Marziali,A., Willis,T.D., & Davis,R.W. (1999) An arrayable flow-through microcentrifuge for high-throughput instrumentation. Proc. Natl. Acad. Sci. USA, 96, 61-66. #13741

  106. Mayfield,L.D., & Corey,D.R. (1999) Automated synthesis of peptide nucleic acids and peptide nucleic acid peptide conjugates. Anal. Biochem., 268, 401-404. #12652

  107. Meldal,M., Tornoe,C., Tedebark,U., Jansson,A.M., Juliano,M.A., Panza,L. & Lay,L. (1999) Azido acids in a novel method of solid phase synthesis. In R.Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 19-22). Mayflower Scientific Limited, Birmingham. #13453

  108. Melnyk,O., Rommens,C., & Gras-Masse,H. (1999) Chemistry of hydrazinopeptides: A new hydroperoxydeamination process. Tetrahedron Lett., 40, 1491-1494. #12601

  109. Micura,R. (1999) Cyclic oligoribonucleotides (RNA) by solid-phase synthesis. Chem. Eur. J., 5, 2077-2082. #13564

  110. Mullah,B., & Livak,K. (1999) Efficient automated synthesis of molecular beacons. Nucleosides Nucleotides, 18, 1311-1312. #13814

  111. Okun,I., & Okun,A. (1999) I.S.D.C.U.Axiom Biotechnologies. Apparatus and method for real-time measurement of cellular response. US Patent. 5,919,646. 904,904, #13269

  112. Owen,M.R., & DeWitt,S.H. (1999) Laboratory automation in chemical development. Process Chemistry in the Pharmaceutical Industry, 429-455. #13024

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