Analytical methods for quality control of combinatorial libraries

William L. Fitch
Affymax Research Institute, 3410 Central Expressway, Santa Clara, CA 95051, U.S.A.

Abstract
This literature review covers the applications of analytical techniques to solid phase organic chemistry and combinatorial chemistry published between June 96 and September 1997. Highlighted are mass spectrometry, NMR, IR and chromatographic analyses of solid phase synthesis reactions and combinatorial libraries.

Keywords
analytical chemistry, combinatorial chemistry, infrared spectroscopy, magic angle spinning, mass spectrometry, nuclear magnetic resonance spectroscopy, solid phase organic chemistry